Harry Kane scored his 36th goal of the season but Bayern Munich let a second-half lead slip to draw 2-2 with Hamburg SV.
Napoli's injury concerns deepened in the second half when David Neres was seen limping off. The stoppage sparked a brief flashpoint between the two sides.
IMAGES from Serie A matches played on Sunday
IMAGES from football matches played across Europe on Sunday
Kevin De Bruyne lifted 19 trophies at City since his 2015 move from German side VfL Wolfsburg -- a haul that includes six Premier League titles and one Champions League crown.
Captain Kevin De Bruyne scored in his penultimate game at Etihad Stadium as Manchester City beat Wolverhampton Wanderers 1-0 on Friday to climb to third in the Premier League and boost their chances of Champions League qualification.
Kevin De Bruyne will leave Manchester City after a decade at the club having lifted six Premier League titles, as well as winning the Champions League and Club World Cup in 2023.
The result was only their second two-goal defeat in a qualifier, the last being the infamous 5-1 home thrashing by England in 2001.
Manchester City gave Kevin De Bruyne a victory in his final appearance at Etihad Stadium, as Omar Marmoush scored a stunner in a 3-1 Premier League win over Bournemouth on Tuesday that saw them climb to third in the table.
'The club and all of our fans will now take the time to deliver a fitting tribute and farewell to one of the greatest players to ever play in the Premier League.'
Premier League takes its responsibility very seriously and do a great job: Michael Owen
France's perfect record in their World Cup qualifying campaign ended as they were held to a 2-2 draw away to Iceland who got a late equaliser in an entertaining Group D clash on Monday.
Winning back-to-back titles for the first time since 1984 is likely to prove a rather more arduous challenge for Liverpool.
Liverpool's Salah named Premier League player of the season, Gravenberch best youngster
The 22-year-old German is Liverpool's most-expensive signing ever, ahead of captain Virgil van Dijk who joined for 75 million pounds in 2017.
Manchester City and Chelsea both secured their Champions League places with victories on the final day of the English Premier League season and Newcastle United joined them despite stumbling to a last-day defeat.
Crystal Palace's Eberechi Eze sparked a massive south London party by scoring the only goal to win the FA Cup 1-0 against Manchester City on Saturday and claim the club's first major trophy in their history.
Ukraine came from behind to beat visitors Belgium 3-1 in the first leg of their Nations League playoff on Thursday
Manchester City's Matheus Nunes scored deep in injury time to salvage a crucial 2-1 Premier League victory over Aston Villa on Tuesday in their breathless chase for a Champions League berth next season.
Sacked Italy manager Luciano Spalletti bowed out with a victory after his side laboured to an uninspired 2-0 home win over Moldova in their World Cup qualification match on Monday.
Wright blasts Man City's Haaland for throwing ball at Arsenal's Gabriel
Some lament the FA Cup having lost much of its romance in recent years, in the face of obsession with the Premier League, but this tie had it in bucket loads.
Guardiola optimistic of De Bruyne's quick return
With 12 games remaining Manchester City are in fourth place with 44 points, just five ahead of 10th-placed Fulham.
Erling Haaland roared back to his best form with a five-goal salvo as Manchester City thumped Luton Town 6-2 at Kenilworth Road to reach the quarter-finals of the FA Cup on Tuesday.
A round-up of Saturday's action in the Premier League.
Images from the Euro 2024 Round of 16 match between France and Belgium, at Dusseldorf Arena, Dusseldorf, Germany, on Monday.
IMAGES from the English Premier League matches played on Saturday.
Shubman Gill met some of Manchester City's treble winning stars during their open-top bus parade in Manchester on Monday.
Jude Bellingham topped the men's overall voting, with the Real Madrid and England midfielder receiving 11,176 selections from his peers.
Youri Tielemans and Kevin De Bruyne gave Belgium a 2-0 win over Romania in an incredible game full of chances
A round-up of Saturday's fifth round action in the FA Cup
IMAGES from the Premier League matches played on Sunday
IMAGES from the Premier League matches played on Sunday.
A round-up of Saturday's action in the Premier League.
Benzema and Courtois helped Real seal a record 14th European title last season while De Bruyne guided City to the Premier League title -- his fourth crown in seven seasons at the club.
Holders Manchester City beat Chelsea 1-0 with a late Bernardo Silva goal on Saturday to reach the FA Cup final after an absorbing end-to-end Wembley semi-final left the exhausted winners still chasing a domestic double.
Germany, once the undisputed kings of European football, enter Euro 2024 with a point to prove
Kevin de Bruyne will miss Belgium's first European Championship match against Russia on Saturday, the Belgian team confirmed.
The approach Slovenia are expected to take on Monday -- a disciplined, deep back five who offer little space, and explosive counter-attacks from long balls -- to put pressure on Portugal.