Ireland won the second ODI by 43 runs on Tuesday after the first game had been washed out by rain.
The board said no replacement will be brought in for Rabada as there is an extended squad in place in the Bio-Secure Environment (BSE), but George Linde has been retained from the Test team as an extra spin-bowling option for the series.
A new-look Indian team, led by Shikhar Dhawan, will be hoping to make a statement and be in the reckoning for next year's 50-over World Cup when the three-match ODI series against South Africa begins in Lucknow on Thursday.
South Africa have named a largely unchanged One-Day International squad for the three-match home series with Bangladesh on March 18-23, with only all-rounder Sisanda Magala missing out after he failed a fitness test.
Kerala's Sanju Samson, 27, was part of the ODI series against Zimbabwe which India won 3-0. He has represented India in seven ODIs and 16 T20Is so far.
The Proteas have named five new players in the squad for the series starting next month.
'We back all the players in our camp, he is a good leader and is valuable in our space. It's just about showing him love and to perform at his best.'
Images from the third and final One-Day International between India and South Africa in Delhi on Tuesday.
Janneman Malan, who was out to the first ball of the match on debut on Saturday, anchored the South African reply, taming his usual swashbuckling style to score 129 not out from 139 balls and lead the home side to victory with nine balls to spare.
Temba Bavuma has recovered from injury and will take charge
Taskin claimed key wickets to ensure a steady procession of home batsmen, Janneman Malan top-scoring with 39.
India, who finished on 240-8, are missing key white-ball players who are in Australia for the Twenty20 World Cup.
South Africa have been fined 20 per cent of their match fee for maintaining a slow over-rate against India in the second ODI in Paarl, the ICC said on Saturday.
He joins injured fast bowler Kagiso Rabada on the sidelines.
IMAGES from the 2nd ODI played between India and South Africa in Ranchi on Sunday.
South Africa have named three front-line spinners in their squad for the Twenty20 World Cup in the United Arab Emirates and Oman but left out opening batsman Janneman Malan.
The Indian team's strategy is expected to undergo paradigm shift with some players getting a subtle yet stern message to lift their games as they face an embarrassing possibility of a clean sweep against South Africa in the third ODI, in Cape Town on Sunday.
Wicketkeeper-batsman Quinton de Kock will be available for the ODI series after his abrupt retirement from Test cricket on Thursday, while all-rounder Dwaine Pretorius earns a recall.
South Africa won their T20 series against world champions West Indies and Ireland, and will once again be captained by Temba Bavuma in both formats.
Openers De Kock (78) and Janneman Malan (91) excelled with the bat as South Africa easily overhauled India's total of 287 for 6 and took an unassailable 2-0 lead in the three-match series.
The loss of Bavuma will further weaken their top six, especially as the experienced Reeza Hendricks has withdrawn from the squad after the birth of his first child, while the in-form Rassie van der Dussen is doubtful for the first match of the series, at least, with a grade one left quadriceps strain.
The winning runs were eventually scored by Mohammad Nawaz (25 from 21) as he hooked Williams to the mid-wicket boundary for six off the penultimate ball of the match to complete a memorable series win.
Images from the second One-Day International between South Africa and India, in Paarl, on Friday.
Deepak Chahar's unavailability due to an ankle injury will complicate selection matters with India looking for a much-improved bowling performance in the must-win second ODI against South Africa, in Ranchi, on Sunday.
Opener Fakhar Zaman smashed his second century in as many matches as Pakistan beat a much-changed South Africa by 28 runs in the third and final One-Day International, in Pretoria on Wednesday, to clinch the series 2-1.
India started well as opener Shikhar Dhawan scored 79 from 84 balls and former captain Virat Kohli 51 from 63, but when they were dismissed the touring side struggled to keep up with the required run-rate and finished on 265 for eight.
India, missing their top players, aim to punch above their weight and seal a memorable series victory against South Africa in the third and final ODI in New Delhi on Tuesday.
'It is a huge day for cricket in Ireland. We will have a couple of beers and enjoy this, but at the same time we have to look to Friday, when we could potentially win a series.'
Wicketkeeper-batsman Mohammad Rizwan smashed a maiden T20 century with seven sixes as Pakistan beat South Africa by three runs
Images from the first One-Day International between South Africa and India, in Paarl, on Wednesday.
India's three-match ODI campaign against South Africa starting on Thursday where the hosts would be aiming to put the 'New Zealand Nightmare' behind them.
Led by Quinton de Kock, South Africa's 44 cricketers, who are part of a men's high performance squad, have returned to training amid the COVID-19 pandemic after getting approval from the country's sports ministry. South Africa has reported more than 1,38,000 COVID-19 cases with over 2,400 deaths.
West Indies spinner Fabian Allen on Wednesday moved into the top 10 of the ICC Men's T20I Player Rankings after featuring in his team's fine showing in the ongoing five-match series against Australia.
Heinrich Klaasen smashed an unbeaten century as South Africa claimed a 74-run victory over Australia in their first one-dayer played on a slow Boland Park wicket on Saturday. After winning the toss, South Africa overcame an early wobble to post 291 for seven in their 50 overs, a total boosted by the maiden ODI ton from middle-order batsman Klaasen, who crashed 123 from 114 balls. Australia were up with the run-rate for much of their reply, but South Africa then strangled the scoring with intelligent use of the slow pitch as the visitors slumped to 217 all out from 45.1 overs.
Fast bowler Dwaine Pretorius took a record 5-17 in South Africa's six-wicket victory.
Images from the rain-curtailed 1st ODI between India and South Africa in Lucknow on Thursday.
For South Africa, Rassie van der Dussen has advanced three slots to the sixth position, just one shy of his career-best, after scores of 34 not out and 52.
Nortje, Markram among players nominated for CSA top awards.
The problem with non-selection of an Indian player in the XI is more to do with lack of matches rather than poor show since they have won both the series that they played in 2021.
Dube smashed an unbeaten 45 off 28 balls while Pandey plundered 81 off 59 balls as India A overcame a poor start to win the rain affected match rather comfortably in the end. Chasing 208 in 30 overs, India A reached the target in 27.5 overs.