Napoli's injury concerns deepened in the second half when David Neres was seen limping off. The stoppage sparked a brief flashpoint between the two sides.
Harry Kane scored his 36th goal of the season but Bayern Munich let a second-half lead slip to draw 2-2 with Hamburg SV.
Bayern Munich, helped by two record-breaking VfL Wolfsburg own goals and two from man-of-the-match Michael Olise, demolished the visitors 8-1 in the Bundesliga on Sunday.
IMAGES from the UEFA Champions League matches played on Tuesday
Rasmus Hojlund scored an equaliser deep into stoppage time as Manchester United salvaged a 1-1 away draw at 10-man Bournemouth in the Premier League on Sunday.
Real Madrid's struggles continued on Sunday as they battled to a 1-1 draw at Girona in LaLiga.
Denmark beat Greece 3-1 at home on Sunday to keep their unbeaten World Cup qualification campaign on track and end the visitors' hopes of reaching next year's tournament, with the battle for Group C supremacy set to go down to the wire.
IMAGES from football matches played across Europe on Sunday
A round-up of Tuesday's action in the UEFA Champions League.
England racked up an eighth successive victory against Wales with a 3-0 cruise in an international friendly at Wembley on Thursday.
Manchester United's Rasmus Hojlund and Alejandro Garnacho ended goal droughts and Bruno Fernandes scored again to earn a 3-0 win at struggling Leicester City.
United manager Ruben Amorim's tough start to life at Old Trafford continues though and the Portuguese has now lost eight of the 14 Premier League matches since he took charge.
Images from the Europa League semi-finals second leg between Manchester United and Athletic Bilbao, Tottenham Hotspur and Bodo/Glimt, on Thursday.
Manchester United clawed back from a goal down to beat Leicester City in a 2-1 fourth-round FA Cup victory on Friday at Old Trafford, thanks to a last-gasp controversial header from veteran defender Harry Maguire plus a strike from Joshua Zirkzee.
Manchester United survived one of the most astonishing FA Cup semi-final comebacks ever to beat second-tier Coventry City on penalties after a spellbinding clash ended 3-3 after extra-time at Wembley Stadium on Sunday.
Brennan Johnson's bundled first-half goal helped Tottenham Hotspur win a scrappy Europa League final 1-0 against Manchester United on Wednesday.
Images from Friday's Premier League matches between Chelsea and Manchester United, Aston Villa and Tottenham Hotspur.
Lazio, who had won all four previous games, were held to a frustrating scoreless draw by a Bulgarian side who came to defend.
A round-up of Thursday's Europa League Round of 16 second leg matches.
United climbed to fourth in the standings on 15 points going into the last round of matches, in a strong position to reach the knockout phase along with Spurs who are sixth with 14 points.
A number of Manchester United players are "not good enough" while some others are being "overpaid", the club's co-owner Jim Ratcliffe said.
Images from the Europa League semi-finals first Leg between Athletic Bilbao and Manchester United, Tottenham Hotspur and Bodo/Glimt.
Forward Rasmus Hojlund scored twice to allow Manchester United to come back from a goal down and get a 2-1 win at six-times Czech champions Viktoria Plzen in the Europa League on Thursday.
'We created loads of chances in our seven (Premier League) games but we have to step up.'
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
Postecoglou moves a step closer to making good on his reputation for securing silverware in his second season at clubs and delivering a first cup for Spurs since they won the League Cup in 2008.
A round-up of Sunday's Nations League second leg quarter-final matches.
IMAGES from the Premier League matches played on Tuesday.
A stoppage-time finish from Rayan Cherki earned Olympique Lyonnais a dramatic 2-2 draw with Manchester United in the first leg of their Europa League quarter-final.
IMAGES from the Europa League matches played on Thursday
A round-up of Saturday's action in the English Premier League.
Alex Ferguson may have been stripped of his Manchester United ambassadorial role last week but his legacy as manager remains a stifling cloud for those following in his footsteps, with Erik ten Hag the latest to be jettisoned after failing to measure up.
IMAGES from the Premier League matches played in England on Sunday.
Eriksen's fairytale Euro comeback spoilt by Slovenia in 1-1 Euro draw
Liverpool moved back to the top of the Premier League with a 2-0 victory at struggling Burnley
A brilliantly-worked goal by Ryan Christie and a Justin Kluivert penalty gave Bournemouth shock 2-0 Premier League win at home to 10-man Arsenal.
Images from the Premier League matches played on Thursday
Manchester United languish 14th in the standings on 19 points, their worst placing to end a calendar year since they were 15th in 1989.
Moises Caicedo's blistering second-half strike cancelled out a Bruno Fernandes penalty as Chelsea salvaged a 1-1 draw with Manchester United on Sunday.
Images from the English Premier League matches played on Sunday night.