Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
City, Liverpool all cruise in respective FA Cup matches played on Saturday.
Researchers have discovered a new chemical reaction that spontaneously makes and breaks a sulphur-sulphur bond at room temperature, offering potential applications in drug development, protein science, biotechnology, and chemical and material science.
Arsenal missed a chance to tighten their grip on the Premier League title race with a 1-1 draw at 10-man Chelsea on Sunday.
Arsenal moved nine points clear in the Premier League after beating Everton 2-0 as 16-year-old Max Dowman became the youngest scorer in league history, while Manchester City dropped points at West Ham.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
James Milner sets a new Premier League record with his 654th appearance as Brighton beat Brentford 2-0, surpassing Gareth Barry's mark.
Arsenal's Eberechi Eze opened his Champions League account with a stunning goal as his team outclassed Bundesliga side Bayer Leverkusen 2-0 at home to reach the quarter-finals with a 3-1 aggregate victory.
While his overall win rate is more than 70%, Liverpool have been a tough nut for Pep Guardiola to crack since he arrived at City in 2016, first under Juergen Klopp and now Arne Slot.
Manchester United's Harry Maguire struck a late header to seal a thrilling 2-1 Premier League victory over Liverpool on Sunday
Arsenal seized control of the Premier League title race as Bukayo Saka's goal secured a priceless 1-0 win at Brighton and Hove Albion and Manchester City could only draw 2-2 at home to relegation-threatened Nottingham Forest.
A summary of Wednesday's action in the UEFA Champions League.
Manchester City halved Arsenal's lead at the top of the Premier League to three points with a 3-0 win over visitors Fulham, while Aston Villa stayed in the frame with a late 1-0 victory at home to Brighton & Hove Albion on Wednesday.
Bayern Munich made it 16 wins from 16 games this season to underline their credentials as early Champions League favourites, beating holders Paris St Germain 2-1 away as Luis Diaz scored two goals and was shown a red card on Tuesday.
Man City ease to 3-0 win over Liverpool as Guardiola celebrates 1,000th game in style
Liverpool coach Arne Slot said he was delighted to have Mohamed Salah returning from Africa Cup of Nations duty soon, despite an apparent falling-out just weeks ago.
Arsenal marked Mikel Arteta's 300th game in charge with a convincing 2-0 home victory over West Ham United in the Premier League on Saturday.
Arsenal extends its lead in the Premier League, while Manchester United strengthens its top-four bid. Chelsea's Cole Palmer shines with a hat-trick, and West Ham earns a crucial win in their fight against relegation.
Dramatic night in the Champions League playoffs as goals, shocks and dominant performances decided the final places in the last 16.
Real Madrid are football's biggest earners, Liverpool best in Premier League
Aston Villa and Chelsea drop crucial points in the Premier League as Leeds and Burnley earn draws; James Milner sets appearance record.
Galatasaray struck twice in extra time to end 10-man Juventus' brave fightback and reach the Champions League's last 16, progressing with a 7-5 aggregate victory.
Arsenal's Premier League lead is cut to four points after a 1-1 draw against Brentford, with goals from Noni Madueke and Keane Lewis-Potter.
IMAGES from the EPL matches played on Saturday
England winger Raheem Sterling has left Chelsea by mutual agreement after being frozen out under successive managers, bringing an end to his troubled two-year spell at Stamford Bridge.
Arsenal maintained a searing pace at the top of the Premier League with a straightforward 2-0 win at Burnley, while Liverpool snapped a dreadful four-match losing run with a 2-0 victory over Aston Villa to climb provisionally to third.
Manchester City set up a League Cup final date with Arsenal after a comprehensive 3-1 second-leg victory over visiting Newcastle United secured a 5-1 aggregate win in their semi-final.
Virgil van Dijk scored with a stunning late header in the second minute of stoppage time to give Liverpool a 3-2 victory over Atletico Madrid in their opening group stage match of the Champions League, at Anfield, on Wednesday.
Crystal Palace scored a stoppage-time winner to edge Liverpool 2-1 while Manchester United and Chelsea lost by an identical 3-1 margin in the English Premier League on Saturday.
Bruno Fernandes milestone and late drama lift Manchester United past Chelsea with a chaotic 2-1 win over Chelsea at Old Trafford
IMAGES from UEFA Champions League matches played on Wednesday
The dramatic late-show moves Mikel Arteta's team into second place, closing the gap to just two points behind the defending champions.
Premier League leaders Arsenal ended their mini-slump with an emphatic 4-0 victory at Leeds United on Saturday to move seven points clear despite Bukayo Saka being ruled out through injury just before kickoff.
Liverpool's Dominik Szoboszlai struck the first telling blow in the Premier League title race with a dazzling free kick late on giving his side a 1-0 victory over rivals Arsenal.
IMAGES from the UEFA Champions League matches played on Wednesday
Winning back-to-back titles for the first time since 1984 is likely to prove a rather more arduous challenge for Liverpool.
Reigning Premier League champions Liverpool honour Portugal forward Diogo Jota, who died in a car crash alongside his brother Andre Silva last month, ahead of the season-opener kick-off against Bournemouth on Friday.
Liverpool have agreed a deal to sign Swedish striker Alexander Isak from Newcastle United on a long-term contract for a British record fee of around 130 million pounds.
Champions Liverpool edged Newcastle United 3-2 in a thrilling finish thanks to a stoppage-time winner by teenaged Premier League debutant Rio Ngumoha.
After Saturday's 2-1 win at Chelsea - their 12th in 13 league matches - Aston Villa have claimed 18 points from losing positions so far this season, more than any other team.