Manchester City will host Liverpool in the FA Cup quarter-finals while Arsenal travel to Southampton as the last-eight draw sets up a blockbuster clash.
Manchester United defeated Aston Villa to strengthen their position in the Premier League top four, while Liverpool were held to a draw by Tottenham Hotspur.
Wolverhampton Wanderers stun Liverpool 2-1 with a 94th-minute winner to revive survival hopes and dent the Reds' top-five push, while Everton and Sunderland claim crucial Premier League victories.
Andy Robertson scored once and set up Mohamed Salah as Liverpool beat Wolves 3-1 at Molineux to reach the FA Cup quarter-finals, while Tottenham Hotspur's Premier League woes deepened after a 3-1 home defeat to Crystal Palace, extending their winless run to 11 matches.
Liverpool secured a dominant win over West Ham, while other Premier League matches saw Brentford edge Burnley in a seven-goal thriller and Everton secure a late victory against Newcastle.
Mario Lemina's early diving header handed Galatasaray a 1-0 victory over Liverpool in their Champions League last-16 first leg on Tuesday.
Eberechi Eze timed his return to the Arsenal scoresheet to perfection with two goals in a 4-1 derby rout of Tottenham Hotspur.
Man City snatch chaotic 2-1 win at Liverpool to stay on Arsenal's heels
Images from the EPL matches played on Saturday.
Arsenal missed the chance to go eight points clear at the top of the Premier League in a turgid 0-0 draw with champions Liverpool.
Arsenal took a seven-point lead at the top of the Premier League after a scoreless draw with Nottingham Forest on Saturday.
Chelsea battled from two goals down to beat West Ham 3-2 in the Premier League on Saturday with a stoppage-time Enzo Fernandez winner.
Liverpool manager Arne Slot must find a way to arrest the team's slide even as the pressure mounts on him, former skipper Steven Gerrard said.
IMAGES from the Premier League matches played on Sunday
Southampton secured a 1-0 victory against Fulham with a late penalty, making them the first non-Premier League club to reach the FA Cup quarter-finals this season.
Barcelona prepares to face Newcastle in the Champions League round of 16, with coach Hansi Flick emphasising the importance of the match. The team aims to improve on last season's semi-final exit and secure their first Champions League title since 2015.
Liverpool striker Alexander Isak is expected to be sidelined for at least a couple of months after breaking his leg and undergoing surgery.
The Egypt forward has been left out of the club's Champions League match against Inter Milan.
Second-placed City would have reduced Arsenal's advantage to two points but instead were frustrated as their winning streak in all competitions was halted at eight.
Liverpool forward Mohamed Salah is destroying his legacy at the club with his fiery reaction to being left out of the side, former Manchester United striker Wayne Rooney said.
Arne Slot planned to have a face-to-face meeting with Mohamed Salah on Friday ahead of Saturday's Premier League match against Brighton & Hove Albion.
Manchester City were drawn against Real Madrid in the Champions League knockout phase for the sixth time since the 2019-20 season after the draw for the last 16, quarterfinals and semifinals was made on Friday.
Benjamin Sesko came off the bench to score the winner as Manchester United beat Everton 1-0 in the Premier League, strengthening their hold on fourth place under Michael Carrick.
Researchers have discovered a new chemical reaction that spontaneously makes and breaks a sulphur-sulphur bond at room temperature, offering potential applications in drug development, protein science, biotechnology, and chemical and material science.
Arsenal moved nine points clear in the Premier League after beating Everton 2-0 as 16-year-old Max Dowman became the youngest scorer in league history, while Manchester City dropped points at West Ham.
Liverpool could be 14th in the table by the time they kick off at West Ham on Sunday afternoon and they will be desperate to steady the ship with three points.
City, Liverpool all cruise in respective FA Cup matches played on Saturday.
Liverpool shrugged off the absence of Mohamed Salah as midfielder Dominik Szoboszlai scored an 88th-minute penalty to give them a 1-0 Champions League win at Inter Milan.
James Milner sets a new Premier League record with his 654th appearance as Brighton beat Brentford 2-0, surpassing Gareth Barry's mark.
Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
Arsenal missed a chance to tighten their grip on the Premier League title race with a 1-1 draw at 10-man Chelsea on Sunday.
Arsenal seized control of the Premier League title race as Bukayo Saka's goal secured a priceless 1-0 win at Brighton and Hove Albion and Manchester City could only draw 2-2 at home to relegation-threatened Nottingham Forest.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
Manchester City halved Arsenal's lead at the top of the Premier League to three points with a 3-0 win over visitors Fulham, while Aston Villa stayed in the frame with a late 1-0 victory at home to Brighton & Hove Albion on Wednesday.
While his overall win rate is more than 70%, Liverpool have been a tough nut for Pep Guardiola to crack since he arrived at City in 2016, first under Juergen Klopp and now Arne Slot.
A summary of Wednesday's action in the UEFA Champions League.
Manchester United's Harry Maguire struck a late header to seal a thrilling 2-1 Premier League victory over Liverpool on Sunday
Liverpool coach Arne Slot said he was delighted to have Mohamed Salah returning from Africa Cup of Nations duty soon, despite an apparent falling-out just weeks ago.
Dramatic night in the Champions League playoffs as goals, shocks and dominant performances decided the final places in the last 16.
Bayern Munich made it 16 wins from 16 games this season to underline their credentials as early Champions League favourites, beating holders Paris St Germain 2-1 away as Luis Diaz scored two goals and was shown a red card on Tuesday.
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