United climbed to fourth in the standings on 15 points going into the last round of matches, in a strong position to reach the knockout phase along with Spurs who are sixth with 14 points.
Spain face Ronald Koeman's Netherlands away on Thursday before returning home for the second-leg on March 23.
Images from Saturday's action in the Premier League.
'I was desperate for them (the fan to be here) of course, for all the fans around the world, for the fans here, but for us as well.'
Jose Mourinho was handed a fine and the ban over his comments about Turkish referees after a game at rivals Galatasaray, where he criticised the match officials in a press conference following the 0-0 Super Lig draw on Monday.
Liverpool resumed their march to a second Premier League title on Sunday with a 2-1 victory over West Ham United.
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
Manchester United were handed a tricky Europa League last 16 tie against Real Sociedad while Tottenham Hotspur will play Dutch side AZ Alkmaar after the draw was held on Friday, but both managers are more concerned about their Premier League form.
Kane's diving header made it 2-0 in the 37th minute to send Tottenham's fans into delirium.
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Manchester City thrashed West Ham United 4-1 in the Premier League on Saturday to claim their first back-to-back wins since October.
IMAGES from the Premier League matches played on Sunday.
Former France striker Karim Benzema was delighted to help Al-Ittihad secure a 4-1 victory over Al-Hilal in a top-of-the-table clash on Saturday, maintaining their dominance in the Saudi Pro League.
Joshua Zirkzee scored the winning penalty for 10-man Manchester United against Arsenal after their hectic FA Cup third round tie finished 1-1 after extra time.
Arsenal were held to a 1-1 Premier League draw by London rivals Fulham on a grey wet Sunday at Craven Cottage as Raul Jimenez scored early for the hosts and William Saliba equalised for the visitors at the start of the second half.
Galatasaray have accused Jose Mourinho of making "racist statements" and said they will initiate criminal proceedings against the Fenerbahce manager over his comments following their 0-0 Super Lig draw on Monday.
A summary of Thursday's action in the Premier League.
Tottenham Hotspur's Brennan Johnson, Dejan Kulusevski and Dominic Solanke got on the scoresheet in a 3-0 victory over 10-man Manchester United in the Premier League on Sunday as the visitors ran roughshod over the bedraggled Old Trafford side.
AS Roma secured their place in the Europa League last 16 with a 3-2 home win over 10-man Porto on Thursday thanks to a Paulo Dybala double, advancing 4-3 on aggregate.
IMAGES from the Premier League matches played across England, on Sunday.
Lewis-Skelly gets England call-up; Recalls Rashford, Henderson return.
With 12 games remaining Manchester City are in fourth place with 44 points, just five ahead of 10th-placed Fulham.
Arsenal, who had 23 shots to Newcastle's seven, piled on the pressure late on to try to reduce the deficit but Newcastle manned the barricades to take a healthy lead to St James' Park.
This was not quite Liverpool back to their best but it was an important statement of intent for Klopp's side that they will not be giving up their title without a fight.
Images from Sunday's action in the Premier League.
Tottenham Hotspur have named Antonio Conte as manager until the summer of 2023, the English Premier League club said on Tuesday, a day after sacking Portuguese coach Nuno Espirito Santo.
Manchester City have now won only once in 11 games in all competitions.
Francisco Moura's second-half strike earned hosts Porto a 1-1 draw against 10-man AS Roma in the first leg of their Europa League knockout round play-off on Thursday.
IMAGES from the English Premier League matches played on Sunday.
United are 13th in the Premier League table and following a 1-1 draw with Dutch side Twente Enschede in the first Europa League match, Ten Hag said speculation about his job was inevitable.
Images from Thursday's action in the Europa League Europa League - Round of 16 Second Leg - matches.
A round-up of Saturday's action in the Premier League.
A summary of Sunday's action in the Premier League.
Qarabag had chances, Tural Baymarov missing from the penalty spot just before the hour mark and Junior hitting the woodwork, but Spurs stayed in control of the match.
Liverpool booked their berth in the League Cup semi-finals with a 2-1 victory over Southampton
Images from Sunday's action in the Premier League.
To mark World Mental Health Day, English footballer Connolly opens up about alcoholism, rehab
According to local media reports, Christopher was fatally shot and was hit in the abdomen by a suspect.
Manchester City spent more than 180 million pounds ($223.58 million) -- more than the combined amount paid by the other 19 English top-flight clubs in a relatively quiet window.
