Manchester City will host Liverpool in the FA Cup quarter-finals while Arsenal travel to Southampton as the last-eight draw sets up a blockbuster clash.
Aston Villa and Chelsea drop crucial points in the Premier League as Leeds and Burnley earn draws; James Milner sets appearance record.
Liverpool secured a dominant win over West Ham, while other Premier League matches saw Brentford edge Burnley in a seven-goal thriller and Everton secure a late victory against Newcastle.
Wolverhampton Wanderers stun Liverpool 2-1 with a 94th-minute winner to revive survival hopes and dent the Reds' top-five push, while Everton and Sunderland claim crucial Premier League victories.
Man City snatch chaotic 2-1 win at Liverpool to stay on Arsenal's heels
Arsenal maintained control of the Premier League title race as they chiselled out a nervy 2-1 win over London rivals Chelsea to open up a five-point lead at the top of the table on Sunday.
Manchester United have sacked head coach Ruben Amorim, the Premier League club said on Monday.
The 44-year-old inherits a team in crisis, sitting seventh in the Premier League table -- a whopping 17 points behind leaders Arsenal -- and eliminated from both domestic cups.
Manchester City halved Arsenal's lead at the top of the Premier League to three points with a 3-0 win over visitors Fulham, while Aston Villa stayed in the frame with a late 1-0 victory at home to Brighton & Hove Albion on Wednesday.
Manchester City blew a two-goal lead to draw 2-2 at Tottenham Hotspur on Sunday as a moment of magic by home forward Dominic Solanke handed Arsenal a huge Premier League title boost.
Manchester United's Benjamin Sesko scoring a stoppage-time equaliser to deny 18th-placed West Ham United a 1-0 win.
Premier League leaders Arsenal ended their mini-slump with an emphatic 4-0 victory at Leeds United on Saturday to move seven points clear despite Bukayo Saka being ruled out through injury just before kickoff.
Chelsea battled from two goals down to beat West Ham 3-2 in the Premier League on Saturday with a stoppage-time Enzo Fernandez winner.
Liverpool coach Arne Slot said he was delighted to have Mohamed Salah returning from Africa Cup of Nations duty soon, despite an apparent falling-out just weeks ago.
Real Madrid are football's biggest earners, Liverpool best in Premier League
Goals from Omar Marmoush and Antoine Semenyo powered Manchester City to a muchneeded 20 home win over Wolverhampton Wanderers on Saturday, lifting Pep Guardiola's men provisionally to within four points of leaders Arsenal in the Premier League title race.
Manchester United loosened Arsenal's grip on the Premier League title race with a 3-2 win in north London on Sunday.
Manchester United have turned to one of their own, appointing their former midfielder Michael Carrick to steady the ship as interim manager until the season's end, the Premier League club said on Tuesday.
Images from the EPL matches played on Saturday.
IMAGES from Premier League matches played on Sunday.
Antoine Semenyo has bewildered defences with 10 goals and three assists this season for Bournemouth.
'The only thing I can do is on the pitch -- to give my all. I won't always be technically perfect, but I will always give 100% for the team.'
Chelsea parted ways with Enzo Maresca on Thursday, a dramatic fall from grace for the Italian who was named manager of the month for November before the club won just one of their last seven league games to fall out of the Premier League title race.
Chelsea's Enzo Fernandez scored a smash-and-grab goal deep in injury time to salvage a 1-1 draw with Manchester City on Sunday.
While there are suggestions that Ruben Amorim's comments at Sunday's press conference triggered his axing, the verdict was clear given his under-performance in the hot seat.
'Imagine one player and now he's perfect but he will arrive with three kilos more. He will (stay) in Manchester. He will not travel to Nottingham Forest.'
Arsenal's Premier League title prospects were enhanced without them even kicking a ball on Wednesday as their closest challengers Manchester City and Aston Villa both dropped points.
Liverpool striker Alexander Isak is expected to be sidelined for at least a couple of months after breaking his leg and undergoing surgery.
Second-placed City would have reduced Arsenal's advantage to two points but instead were frustrated as their winning streak in all competitions was halted at eight.
Liverpool forward Mohamed Salah is destroying his legacy at the club with his fiery reaction to being left out of the side, former Manchester United striker Wayne Rooney said.
'We did a very good job that no one is going to remember tomorrow, because what matters is the result.'
After Saturday's 2-1 win at Chelsea - their 12th in 13 league matches - Aston Villa have claimed 18 points from losing positions so far this season, more than any other team.
IMAGES from the Premier League matches played on Sunday
Promoted Sunderland, who have defied expectations to stay in the top half of the Premier League table, could be the worst affected with six players going to the tournament, while the likes of Fulham, Manchester United, Burnley and Crystal Palace will also have to make do without some key personnel.
Manchester City seized the opportunity of Arsenal's 2-1 loss at Aston Villa earlier in the day to climb within two points of the leaders.
While Wolves are looking down, United are beginning to look up and while there were times in the first half when they looked vulnerable, their second-half display was silky.
Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
Premier League leaders Arsenal needed two own goals, the second deep in stoppage time, to scrape a 2-1 home win over bottom club Wolverhampton Wanderers and open a five-point gap, while earlier on Saturday Mohamed Salah put aside a tumultuous week to help Liverpool beat Brighton and Hove Albion 2-0.
Manchester City manager Pep Guardiola was furious at several decisions during the 2-1 loss at St James' Park and appeared to take out his frustration on a pitch-side TV cameraman after the final whistle.
Midfielder Phil Foden delivered in dramatic fashion, scoring in the first and 91st minutes, to seal Manchester City's 3-2 victory over Leeds United.
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