Getafe secured a surprising 1-0 victory against Real Madrid in LaLiga, courtesy of Martin Satriano's stunning volley, leaving Barcelona with a four-point lead at the top of the table.
Lyon sealed top spot in the Europa League standings while Roma survived a red-card scare to reach the last 16 on a chaotic final league-phase night.
AS Roma took a big step towards qualifying for the Europa League last 16 with a 2-0 win over VfB Stuttgart on Thursday.
Aston Villa secured a 2-1 victory at Basel on Thursday, with goals from Evann Guessand and Youri Tielemans keeping their Europa League campaign on a strong footing.
Lyon thump Maccabi Tel Aviv to go top, Forest keep on winning
Nottingham Forest handed manager Sean Dyche the perfect debut with a 2-0 home win over Porto in the Europa League on Thursday, with both goals coming from the penalty spot.
Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
On debut, substitute Marcus Rashford became the first Englishman to play a first-team game for Barcelona since former England striker Gary Lineker in 1989.
What was meant to be a weekend of solidarity against homophobia in Ligue 1 descended into controversy and embarrassment for French football, as players refused to wear campaign symbols, one striker boycotted his team's match, and a homophobic slur was heard in a stadium tunnel.
Olympique Lyonnais coach Paulo Fonseca has been suspended for nine months by the French Professional Football League (LFP), following a confrontation with referee Benoit Millot.
Spain's teenage sensation Lamine Yamal inspired his country to a thrilling 5-4 win over France on Thursday to send the holders through to their third successive Nations League final where they will face Iberian neighbours Portugal.
A summary of Thursday's Europa League quarter-finals second-leg.
A round-up of Saturday's action the Bundesliga, Ligue 1
A stoppage-time finish from Rayan Cherki earned Olympique Lyonnais a dramatic 2-2 draw with Manchester United in the first leg of their Europa League quarter-final.
A round-up of Thursday's Europa League Round of 16 second leg matches.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
Manchester United were handed a tricky Europa League last 16 tie against Real Sociedad while Tottenham Hotspur will play Dutch side AZ Alkmaar after the draw was held on Friday, but both managers are more concerned about their Premier League form.
A summary of Saturday's action in LaLiga, Serie A, Bundesliga and Ligue 1.
United climbed to fourth in the standings on 15 points going into the last round of matches, in a strong position to reach the knockout phase along with Spurs who are sixth with 14 points.
IMAGES from Europa League matches played on Thursday.
Bundesliga leaders Bayern Munich powered past third-placed Eintracht Frankfurt 4-0 with an impressive display of high-pressing football on Sunday.
Qarabag had chances, Tural Baymarov missing from the penalty spot just before the hour mark and Junior hitting the woodwork, but Spurs stayed in control of the match.
Argentina host Chile at the Monumental stadium in Buenos Aires on September 5 before facing Colombia five days later in Barranquilla.
Forward Rasmus Hojlund scored twice to allow Manchester United to come back from a goal down and get a 2-1 win at six-times Czech champions Viktoria Plzen in the Europa League on Thursday.
IMAGES from the Europa League matches played on Thursday
IMAGES from the Europa League matches played on Thursday
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Paris St Germain were confirmed as Ligue 1 champions for a record-extending 12th time on Sunday after second-placed AS Monaco lost 3-2 at Olympique Lyonnais.
France overcame a slow start to beat neighbours Belgium 2-0 for their first points of the Nations League campaign.
Vinicius Jr came off the bench to score once and set up another goal to steer champions Real Madrid to a 4-1 fightback victory over Espanyol.
French football was again marred by violence after Olympique de Marseille's Ligue 1 match against Olympique Lyonnais was called off on Sunday when the visitors' bus and some fans were pelted with stones and beer bottles, injuring Lyon coach Fabio Grosso.
Arsenal took the race to the final day last season and are strongly tipped to end Manchester City's dominance this time.
A summary of the concluding day's action in the German Cup, French Cup and La Liga.
La Liga leaders Real Madrid were held to a frustrating 1-1 draw at lowly city rivals Rayo Vallecano on Sunday as Joselu's early strike was cancelled out by Raul de Tomas' penalty, a result that could spice up the title race with surprise package Girona.
Portuguese midfielder Bruno Fernandes has been named as the new captain of Manchester United, the Premier League club said on Thursday.
Real Madrid's Karim Benzema, who won the 2022 Ballon d'Or award, is also in the shortlist.
Karim Benzema will leave Real Madrid as a free agent in the close season after 14 trophy-laden years
'Yesterday, he trained normally, and today he's taken this decision. We have accepted it. I spoke to him this morning, and he said he was leaving, and I understood.'
Barcelona will face a struggling Galatasaray team who are 13th in the Turkish top-flight.
While Catalina Usme fired Colombia to a 1-0 win over Jamaica, France entered the quarters with a win over Morocco.