After a six-match unbeaten start to his reign as Liverpool manager Juergen Klopp came down to earth with a bump as his side lost 2-1 to Crystal Palace in the Premier League on Sunday.
Karius's manager Juergen Klopp said the keeper will be backed by the club.
However, one goal proved enough for City who picked up their sixth successive league win to move four points clear of Liverpool, who host Aston Villa later on Saturday, at the top of the standings.
Liverpool ripped apart Manchester City with three goals inside the opening 31 minutes as they won their Champions League quarter-final, first leg tie 3-0 on Wednesday.
Lucas Bergvall scored his first goal for Tottenham Hotspur to give his side a surprise 1-0 victory over holders Liverpool in the first leg of their League Cup semi-final on Wednesday.
A round-up of Wednesday's action in the Premier League
Liverpool's Luis Diaz scored a hat-trick as they maintained their perfect Champions League campaign with a barnstorming second-half display in a 4-0 victory over Xabi Alonso's Bayer Leverkusen at Anfield on Tuesday.
IMAGES from the Premier League matches played on Sunday.
News of all that's transpired on and off the football field.
A summary of Thursday's action in the Premier League.
A summary of Wednesday's Champions League Round of 16, Second Leg, matches.
Former Liverpool manager Juergen Klopp said he has no immediate plans to return to management.
A round-up of Wednesday's UEFA Champions League last-16 first leg matches.
Liverpool manager Roy Hodgson has said that he has done everything possible to keep striker Fernando Torres at the club.
IMAGES from the Premier League match played between Liverpool and Luton at Anfield on Wednesday
Liverpool strolled to a 2-0 victory over Brentford, while Newcastle drew 1-1 at Bournemouth.
AC Milan will have to be perfect defensively when they host Premier League side Liverpool in their Champions League opener at San Siro, manager Paulo Fonseca said on Monday.
Arsenal's title hopes hit with 2-0 loss to Villa as Man City get boost
On Sunday, after Liverpool's final game of the season, a 2-0 home win over Wolverhampton Wanderers, Klopp led the Anfield crowd in a song for the incoming manager.
Liverpool's Slot not nervous ahead of Anfield debut
Mohamed Salah's early penalty in the return match on Thursday gave Liverpool a 1-0 victory in Italy but Klopp's side went out 3-1 on aggregate.
'I've got options on the pitch and off the pitch, I have got a bit of thinking to do in the next few weeks'
Images from the English Premier League matches played on Saturday.
Former Borussia Dortmund manager Juergen Klopp is expected at Anfield on Thursday as the German edges closer to becoming Brendan Rodgers' successor at Liverpool.
City must win at Spurs or Arsenal will be champions says Guardiola
Marcus Rashford and Joshua Zirkzee bagged two goals apiece as Manchester United thumped Everton 4-0 on Sunday in new manager Ruben Amorim's first Premier League match at Old Trafford.
Liverpool lost the plot in Atalanta defeat, says Klopp
His agent Bo Gustavsson told Reuters he had passed away Monday morning.
IMAGES from the UEFA Champions League matches played on Wednesday
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
Tracking the key moves this week in the European transfer market
A summary of Sunday's action in the Premier League.
Manchester City won an unprecedented fourth straight English top flight title with a 3-1 win over West Ham United.
Images from the English Premier League matches played on Saturday
Following Manchester United's 7-0 drubbing at the hands of Liverpool at Anfield on Sunday, manager Ten Hag among former players came down heavily on their 'embarrassing' performance.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
'It is that I am, how can I say it, running out of energy.'
Twenty-year-old Conor Bradley scored his first goal for Liverpool and claimed two assists as Juergen Klopp's team moved five points clear at the top
Liverpool cruised into the fifth round of the FA Cup with a 5-2 rout of Championship side Norwich City on Sunday, to kick off Juergen Klopp's long goodbye at Anfield.