Getafe secured a surprising 1-0 victory against Real Madrid in LaLiga, courtesy of Martin Satriano's stunning volley, leaving Barcelona with a four-point lead at the top of the table.
Lyon sealed top spot in the Europa League standings while Roma survived a red-card scare to reach the last 16 on a chaotic final league-phase night.
AS Roma took a big step towards qualifying for the Europa League last 16 with a 2-0 win over VfB Stuttgart on Thursday.
Lyon thump Maccabi Tel Aviv to go top, Forest keep on winning
Aston Villa secured a 2-1 victory at Basel on Thursday, with goals from Evann Guessand and Youri Tielemans keeping their Europa League campaign on a strong footing.
Nottingham Forest handed manager Sean Dyche the perfect debut with a 2-0 home win over Porto in the Europa League on Thursday, with both goals coming from the penalty spot.
Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
What was meant to be a weekend of solidarity against homophobia in Ligue 1 descended into controversy and embarrassment for French football, as players refused to wear campaign symbols, one striker boycotted his team's match, and a homophobic slur was heard in a stadium tunnel.
On debut, substitute Marcus Rashford became the first Englishman to play a first-team game for Barcelona since former England striker Gary Lineker in 1989.
Olympique Lyonnais coach Paulo Fonseca has been suspended for nine months by the French Professional Football League (LFP), following a confrontation with referee Benoit Millot.
Spain's teenage sensation Lamine Yamal inspired his country to a thrilling 5-4 win over France on Thursday to send the holders through to their third successive Nations League final where they will face Iberian neighbours Portugal.
A summary of Thursday's Europa League quarter-finals second-leg.
A round-up of Saturday's action the Bundesliga, Ligue 1
A round-up of Thursday's Europa League Round of 16 second leg matches.
A stoppage-time finish from Rayan Cherki earned Olympique Lyonnais a dramatic 2-2 draw with Manchester United in the first leg of their Europa League quarter-final.
United climbed to fourth in the standings on 15 points going into the last round of matches, in a strong position to reach the knockout phase along with Spurs who are sixth with 14 points.
Manchester United were handed a tricky Europa League last 16 tie against Real Sociedad while Tottenham Hotspur will play Dutch side AZ Alkmaar after the draw was held on Friday, but both managers are more concerned about their Premier League form.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
Argentina host Chile at the Monumental stadium in Buenos Aires on September 5 before facing Colombia five days later in Barranquilla.
IMAGES from Europa League matches played on Thursday.
A summary of Saturday's action in LaLiga, Serie A, Bundesliga and Ligue 1.
Qarabag had chances, Tural Baymarov missing from the penalty spot just before the hour mark and Junior hitting the woodwork, but Spurs stayed in control of the match.
Bundesliga leaders Bayern Munich powered past third-placed Eintracht Frankfurt 4-0 with an impressive display of high-pressing football on Sunday.
IMAGES from the Europa League matches played on Thursday
French football was again marred by violence after Olympique de Marseille's Ligue 1 match against Olympique Lyonnais was called off on Sunday when the visitors' bus and some fans were pelted with stones and beer bottles, injuring Lyon coach Fabio Grosso.
Paris St Germain were confirmed as Ligue 1 champions for a record-extending 12th time on Sunday after second-placed AS Monaco lost 3-2 at Olympique Lyonnais.
IMAGES from the Europa League matches played on Thursday
Forward Rasmus Hojlund scored twice to allow Manchester United to come back from a goal down and get a 2-1 win at six-times Czech champions Viktoria Plzen in the Europa League on Thursday.
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
France overcame a slow start to beat neighbours Belgium 2-0 for their first points of the Nations League campaign.
Portuguese midfielder Bruno Fernandes has been named as the new captain of Manchester United, the Premier League club said on Thursday.
Barcelona will face a struggling Galatasaray team who are 13th in the Turkish top-flight.
Real Madrid's Karim Benzema, who won the 2022 Ballon d'Or award, is also in the shortlist.
A summary of the concluding day's action in the German Cup, French Cup and La Liga.
Vinicius Jr came off the bench to score once and set up another goal to steer champions Real Madrid to a 4-1 fightback victory over Espanyol.
The 19-year-old Mbappe followed up a domestic treble with Paris St Germain with a string of impressive performances in France's World Cup winning campaign.
Arsenal took the race to the final day last season and are strongly tipped to end Manchester City's dominance this time.
Karim Benzema will leave Real Madrid as a free agent in the close season after 14 trophy-laden years
Paris St Germain completed a domestic treble as they beat Olympique Lyonnais 6-5 on penalties to lift the French League Cup on Friday with the match ending in a 0-0 stalemate after regular and extra time. Second-half substitute Pablo Sarabia scored PSG's final penalty in the shootout after goalkeeper Keylor Navas had saved Bertrand Traore's spot kick to give the Ligue 1 champions and French Cup winners their ninth League Cup trophy.
La Liga leaders Real Madrid were held to a frustrating 1-1 draw at lowly city rivals Rayo Vallecano on Sunday as Joselu's early strike was cancelled out by Raul de Tomas' penalty, a result that could spice up the title race with surprise package Girona.