Sindhu is the only Indian to feature in the women's singles competition.
Srikanth lost 21-23, 8-21 to Korea's Chia Hao Lee, continuing his dismal run in international circuit this season.
Olympic medallist P V Sindhu is also missing in action as she recovers from an injury.
The 21-year-old Sen, who won a bronze in the 2021 World Championships, has been in brilliant form, starting the year with a gold medal at the Yonex-Sunrise India Open before finishing runner-up, at the prestigious All England Open Championships and also at the German Open.
A year ago, following the World Championships, Sen underwent nasal surgery to treat a deviated septum. What followed was an extended recovery process that took eight months.
Returning to action after recovering from a back injury, star India shuttler H S Prannoy emerged as the lone Indian survivor at the Japan Masters, advancing to the second round after a gritty victory in Kumamoto on Wednesday.
Two-time Olympic medallist Sindhu will next play Japan's Natsuki Nidaira, while Sen will be up against Ygor Coelho of Brazil.
Double Olympic medallist PV Sindhu, Commonwealth Games gold medallist Lakshya Sen, Tokyo Olympic B Sai Praneeth and Ruthvika Shivani Gadde will be in action later on Wednesdat.
Kidambi Srikanth, Priyanshu Rajawat and Kiran George won their respective men's singles round-of 16 matches to advance to the quarterfinals late on Thursday night.
'The boys did it. First-ever Thomas Cup for India.'
Defending champions India's hopes of entering the Thomas Cup knockout stage as group topper were dashed by a clinical Indonesia who emerged 4-1 winners in their final pool match in Chengdu on Wednesday.
Lakshya Sen fought hard before going down in three games against fifth seed Jonatan Christie of Indonesia in the semi-finals of the Japan Open.
Sindhu, Sen look to regain lost touch in Canada Open
Indian challenge ends after Satwik-Chirag bow out in opening round of China Open
World No 8 Sen zoomed to an early 5-1 lead before dashing to 11-3 at the mid-game break. He kept moving ahead as Prannoy's game crumbled.
Many believe the Thomas Cup victory can do for badminton what the 1983 World Cup triumph did for cricket in India.
The core of the team remains the same with HS Prannoy, Lakshya Sen and Satwiksairaj Rankireddy and Chirag Shetty in good form and the Indian team would hope the rub of the green also goes their way when it begins campaign on Thursday.
With the main draw of the Asian Badminton Championships set to get underway from Wednesday, the struggling Indian shuttlers face an uphill task.
Sen has a 4-2 head-to-head record against his final opponent Li Shi Feng, the reigning All-England champion. Sen had defeated him recently at the Thailand Open.
Lakshya Sen, returning from a break, suffered a first round exit, while Treesa Jolly and Gayatri Gopichand entered the pre-quarters of the Asia Badminton Championship.
Lakshya Sen, who won both his matches to play his part in the silver medal-winning effort in men's team event, too dropped one spot to world number 15. Kidambi Srikanth gained a spot to 20th.
The FIR, filed on Thursday by M Goviappa Nagaraja, alleged that the 21-year-old reigning Commonwealth Games champion, along with his brother Chirag Sen, had fudged their age to get into playing age-group tournaments since 2010.
Swiss Open champion Satwiksairaj Rankireddy and Chirag Shetty strengthened their world number six position, while women's doubles pairing of Treesa Jolly and Gayatri Gopichand was static at the 18th position.
Prannoy is only seeded Indian player at No. 7 in the men's singles draw of 32 as he will begin his campaign against Loh Kean Yew of Singapore, against whom the Indian has a 4-1 win-loss record.
Lakshya Sen and Saina Nehwal made impressive starts at the Indonesia Masters Super 500 badminton tournament, advancing to the second round of men's and women's singles respectively with contrasting victories in Jakarta on Wednesday.
In the men's doubles, Satwiksairaj Rankireddy and Chirag Shetty maintained their world number two ranking, although they lost in the quarter-finals of the World Championships going down to Kim Astrup-Anders Rasmussen.
A summary of Indian athletes' showing on the concluding day of the Commonwealth Games.
Two-time Olympic-medallist P V Sindhu made a winning return from a lengthy injury lay-off as India stunned formidable China 3-2 in the women's competition of the Badminton Asia Team Championships in Shah Alam, Malaysia on Wednesday.
Indian women's badminton star Saina Nehwal crashed out of the women's singles competition in the first round after a loss to China's Zhang Yiman. She lost the match 17-21, 21-19,11-21. After being a game down, Nehwal made a comeback in the second game but lost the final one.
P V Sindhu and Aakarshi Kashyap advanced to the women's singles second round at the Denmark Open Super 750 badminton tournament.
This was Sen's second straight defeat against Chou in less than a month.
P V Sindhu and Lakshya Sen progressed to the quarter-finals at the Canada Open Super 500 tournament
Satwik-Chirag pair achieves career-best world no. 2 ranking
Coaching is the toughest job: Saina Nehwal on her future
India's Kiran Geroge moves to quarters, Ashmita bows out of Thailand Open
Prime Minister Narendra Modi on Monday hailed Kidambi Srikanth's silver medal win in the World Badminton Championships, saying it will inspire several sportspersons and further interest in badminton.
HS Prannoy, who occupies the 8th spot, is the best ranked Indian in the men's singles while Lakshya Sen and Kidambi Srikanth are placed 19th and 20th respectively.
Double Olympic medallist PV Sindhu survived some tense moments before progressing to the women's singles second round, but it was curtains for Lakshya Sen and Kidambi Srikanth in the men's singles at the Badminton Asia Championships, in Ningbo, China, on Wednesday.
Satwik and Chirag jumped one spot in the latest BWF rankings to regain the fifth place.
On November 30, President Droupadi Murmu presented the Sports and Adventure Awards 2022 at Rashtrapati Bhavan.