Crystal Palace have never won the FA Cup, Aston Villa last lifted the trophy in 1957 and Nottingham Forest have not managed it since 1959 but all three clubs go into this weekend's semi-finals genuinely believing this could be their year.
A much-changed Liverpool were dumped out of the FA Cup by struggling second-tier side Plymouth Argyle, who pulled off a stunning 1-0 fourth round win.
Everton's Ashley Young came on as a second-half substitute but his 18-year-old son Tyler remained on the Peterborough bench.
Some lament the FA Cup having lost much of its romance in recent years, in the face of obsession with the Premier League, but this tie had it in bucket loads.
A round-up of Saturday's fifth round action in the FA Cup
From Royal Challengers Bengaluru's historic first IPL title to star javelin thrower Neeraj Chopra finally breaking the iconic 90-meter mark to India women winning their first cricket World Cup, this was the year of long-awaited victories and record-breaking feats.
Reach fifth round for first time in 10 years
Manchester United clawed back from a goal down to beat Leicester City in a 2-1 fourth-round FA Cup victory on Friday at Old Trafford, thanks to a last-gasp controversial header from veteran defender Harry Maguire plus a strike from Joshua Zirkzee.
Promoted Sunderland, who have defied expectations to stay in the top half of the Premier League table, could be the worst affected with six players going to the tournament, while the likes of Fulham, Manchester United, Burnley and Crystal Palace will also have to make do without some key personnel.
Joshua Zirkzee scored the winning penalty for 10-man Manchester United against Arsenal after their hectic FA Cup third round tie finished 1-1 after extra time.
Aston Villa newcomer Marco Asensio struck twice in the second half to lead the Premier League team to a 2-0 victory over second-tier Cardiff City on Friday and into the FA Cup quarter-finals for the first time in 10 years.
A summary of Saturday's action in the FA Cup third round.
Arsenal's miserly defence has conceded three Premier League goals so far this season and manager Mikel Arteta hopes their fortress-like foundation can finally deliver the silverware that has eluded the North London club for so long.
Manchester United survived one of the most astonishing FA Cup semi-final comebacks ever to beat second-tier Coventry City on penalties after a spellbinding clash ended 3-3 after extra-time at Wembley Stadium on Sunday.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
Cash on target as Villa hand Man City their first defeat since August
IMAGES from the Premier League matches played on Sunday
Holders Manchester City beat Chelsea 1-0 with a late Bernardo Silva goal on Saturday to reach the FA Cup final after an absorbing end-to-end Wembley semi-final left the exhausted winners still chasing a domestic double.
Luton Town knocked out Everton and sixth tier Maidstone United upset Championship Ipswich Town
Vitaliy Mykolenko's 39th-minute own goal had put Luton ahead before Jack Harrison cheered the Everton faithful with an equaliser in the 55th minute, hammering in a low shot that Luton keeper Tim Krul allowed to let slip through his hands.
Chelsea had looked in full control at halftime after goals from Marc Cucurella and Cole Palmer
Erik ten Hag's side will face Championship (second-tier) outfit Coventry City in the semis after they upset Wolverhampton Wanderers 3-2 on Saturday.
IMAGES from the FA Cup final played between Manchester City and Manchester United, at Wembley Stadium, London, Britain, on Saturday
Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
The regional fire department of Castille-Leon, where Zamora is located, said on its website a car crashed shortly after midnight on Thursday and burst into flames, with two men, aged 28 and 26, found dead.
Championship (second tier) side Rotherham, who haven't made it through to the fourth round of the competition since 2001-02, kept their composure early on as Fulham controlled the play.
Newcastle United made light work of north-east rivals Sunderland as Alexander Isak's double secured a 3-0 win and a place in the FA Cup fourth round at the Stadium of Light on Saturday.
Ruben Amorim apologised to Manchester United supporters after his reign reached a new low with a humiliating elimination from the League Cup by fourth-tier Grimsby Town on Wednesday.
n own goal by Jakub Kiwior and a thumping late strike by Luis Diaz sealed a 2-0 victory for Liverpool at Arsenal
Liverpool's Portuguese forward Jota, 28 and his brother Andre Silva, died in a car crash in northwestern Spain early on Thursday, July 3, when their Lamborghini veered off the road and burst into flames, authorities said.
Manchester City clinched a 1-0 victory at Tottenham Hotspur, while Chelsea were held to a 0-0 draw at home by Aston Villa.
The commanding scoreline in the cross-town London derby came despite Chelsea's midfield talisman Cole Palmer being ruled out after he felt discomfort on the pitch during the pre-match warmup.
The move came after Manchester-born Rashford, who made 426 senior appearances and scored 138 goals for United in all competitions, fell out of favour with manager Ruben Amorim.
Chelsea outplay Villa in FA Cup
England midfielder Jack Grealish joined Everton on a season-long loan from Manchester City on Tuesday as he seeks to restart his stalled international career.
Crystal Palace beat Premier League champions Liverpool 3-2 on penalties to win the Community Shield after an entertaining 2-2 draw at Wembley on Sunday.
A fan who wore an offensive football shirt referencing the Hillsborough disaster to the FA Cup final has been banned from attending football games for four years.
Manchester City manager Pep Guardiola admitted he was surprised that Norwegian striker Erling Haaland declined to take a penalty for his side in Saturday's FA Cup final against Crystal Palace with the kick subsequently being missed by Omar Marmoush.
Arsenal's Calafiori secures 1-0 win at Manchester United; Crystal Palace hold Chelsea to 0-0 draw.
Rashford absence an 'internal matter', says Ten Hag