Harry Kane scores twice as Bayern Munich beat Eintracht Frankfurt 3-2 to go nine points clear in the Bundesliga; Monaco stun Lens in Ligue 1.
Championship side Oxford United beat League Two's MK Dons on penalties after their match ended 1-1, while a couple of League One teams moved on, with Wigan Athletic beating Championship side Preston North End 1-0, and Port Vale defeating League Two's Fleetwood Town 1-0.
IMAGES from the UEFA Champions League matches played on Wednesday.
Liverpool striker Alexander Isak is expected to be sidelined for at least a couple of months after breaking his leg and undergoing surgery.
Barcelona to return to Camp Nou on Saturday after two years
IMAGES from the UEFA Champions League matches played on Tuesday
Liverpool shrugged off the absence of Mohamed Salah as midfielder Dominik Szoboszlai scored an 88th-minute penalty to give them a 1-0 Champions League win at Inter Milan.
Liverpool have signed French striker Hugo Ekitike from Eintracht Frankfurt, the English Premier League side announced on Wednesday.
A summary of Wednesday's action in the UEFA Champions League.
Eintracht Frankfurt beat 10-man West Ham United 1-0 in their Europa League semi-final
IMAGES from the EPL matches played on Saturday
Manchester United, winners of the competition in 2017, will have a lot of travelling to do to Eastern Europe after being drawn alongside Kazakhstan side Astana, Serbia's Partizan Belgrade and Dutch side AZ Alkmaar.
A round-up of Tuesday's action in the UEFA Champions League.
Erling Haaland is the tenth player to reach the landmark of 50 goals in the UEFA Champions League and fastest to do so, beating the 62-match record of Ruud van Nistelrooy.
IMAGES from the UEFA Champions League matches played on Wednesday
Liverpool talisman Mo Salah and substitute Federico Chiesa struck late goals as the Premier League champions began the defence of their title by beating Bournemouth 4-2 in a thriller on the opening night of the season at Anfield on Friday.
Mouth-watering matches lined up as PSG to face Bayern and Barcelona in Champions League opening stage.
Bayern Munich will secure the Bundesliga title on Saturday
Winning back-to-back titles for the first time since 1984 is likely to prove a rather more arduous challenge for Liverpool.
Son Heung-min said returning to his home country South Korea for the World Cup qualifiers against Oman and Jordan has brought him immense joy
Manchester United were handed a tricky Europa League last 16 tie against Real Sociedad while Tottenham Hotspur will play Dutch side AZ Alkmaar after the draw was held on Friday, but both managers are more concerned about their Premier League form.
Nuno Espirito Santo's side took the lead after five minutes when a corner fell to Elliot Anderson on the edge of the area and his powerful deflected drive found the net.
A summary of Saturday's action in Ligue 1, LaLiga and Bundesliga.
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Bundesliga leaders Bayern Munich powered past third-placed Eintracht Frankfurt 4-0 with an impressive display of high-pressing football on Sunday.
Manchester City manager Pep Guardiola has noticed an increase in opposing teams adopting a man-marking approach.
A round-up of Thursday's Europa League Round of 16 second leg matches.
A stoppage-time finish from Rayan Cherki earned Olympique Lyonnais a dramatic 2-2 draw with Manchester United in the first leg of their Europa League quarter-final.
A summary of Thursday's Europa League quarter-finals second-leg.
United climbed to fourth in the standings on 15 points going into the last round of matches, in a strong position to reach the knockout phase along with Spurs who are sixth with 14 points.
Manchester City spent more than 180 million pounds ($223.58 million) -- more than the combined amount paid by the other 19 English top-flight clubs in a relatively quiet window.
IMAGES from football matches played across Europe on Wednesday.
A summary of Saturday's action in the LaLiga, Serie A and Bundesliga.
IMAGES from Europa League matches played on Thursday.
Qarabag had chances, Tural Baymarov missing from the penalty spot just before the hour mark and Junior hitting the woodwork, but Spurs stayed in control of the match.
Lazio, who had won all four previous games, were held to a frustrating scoreless draw by a Bulgarian side who came to defend.
IMAGES from the Europa League matches played on Thursday
Forward Rasmus Hojlund scored twice to allow Manchester United to come back from a goal down and get a 2-1 win at six-times Czech champions Viktoria Plzen in the Europa League on Thursday.
Bayern Munich earned a nervous 1-0 win at St Pauli thanks to a sensational 28-metre drive from Jamal Musiala to stay unbeaten.
The win leaves United in 15th place in the Europa League standings on six points from four games.