The win leaves United in 15th place in the Europa League standings on six points from four games.
Robert Lewandowski smashed home a rebound to earn Barcelona a 2-1 win against Athletic Bilbao in an absorbing LaLiga clash on Saturday.
Barcelona's Robert Lewandowski scored a quick-fire second-half double to set the leaders on course for a thrashing of Real Madrid.
IMAGES from football matches played across European leagues on Saturday
All the action from football matches played in Europe on Wednesday
Piotr Zielinski converted two penalties for Inter Milan as they played out a thrilling 4-4 draw with Juventus.
Leverkusen's Schick scores hat-trick in comeback win over Heidenheim.
Real Madrid have avoided defeat in their last 41 LaLiga games, the second best streak by a team in the competition's history.
IMAGES from the soccer matches played across leagues on Friday
Barcelona will face a struggling Galatasaray team who are 13th in the Turkish top-flight.
Roundup of the matches being held across major football leagues in Europe on Sunday
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Kolo Muani replaces injured Nkunku in France's World Cup squad
Eintracht Frankfurt won the Europa League final after holding their nerve to beat Rangers 5-4 in a clinical penalty shootout as they claimed their first European trophy in 42 years.
Champions League winners Real Madrid outclassed Eintracht Frankfurt 2-0 on Wednesday to clinch the UEFA Super Cup for a record-equalling fifth time and kick off their season with a trophy.
Barcelona were shaken up by Eintracht Frankfurt but took a first step in their bid to reach the Europa League last four as a second-half goal by Ferran Torres salvaged a 1-1 comeback away draw in their quarter-final first leg on Thursday.
A summary of Thursday's second leg quarter-final matches in the Europa League.
Manchester United breezed into the next round with a 6-1 aggregate win over Club Brugge
Real have not lost any of their last six games against Liverpool in the Champions League
Bayern Munich stumbled to a 1-1 draw against visiting Eintracht Frankfurt on Saturday to leave them with only a slim Bundesliga lead after being held for the third game in a row with the same scoreline.
Bayer Leverkusen beat Freiburg 3-2 to edge closer to a first ever Bundesliga title.
Holders Real Madrid will play 2021 winners Chelsea in the Champions League quarter-finals while Manchester City's Pep Guardiola will visit his former club Bayern Munich.
If two or more clubs are level on points at the end of the group stage, a number of criteria will be taken into consideration to decide the qualifiers for the next round, starting with the head-to-head record among the teams in question. It then goes to superior goal difference and then goals scored in those matches.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
While he only made one late substitution in the 2-1 victory over England, Deschamps used the bench more against Morocco.
Barcelona have reached the semis only once since winning the Champions League in 2014-15.
Chelsea will face Dynamo Kiev at home in the first leg of their Europa League last-16 tie, while London rivals Arsenal will travel to Rennes following Friday's draw in Nyon, Switzerland.
Germans cannot afford any slip-up against the Japanese and risk a potential early exit again.
IMAGES from the football matches played across Europe on Sunday.
Manchester City's Erling Haaland faces Borussia Dortmund and Barcelona's Robert Lewandowski meets Bayern Munich after the Champions League group-stage draw was made on Thursday.
The FIFA 2022 World Cup will kick-off in Qatar on Sunday, November 20. Here is a list of the 26-man squads playing in the quadrennial global football extravaganza.
Standard had their professional licence rescinded on April 8 after the Belgian football association found they had not paid premiums owed to players.
A round-up of Tuesday's action in the UEFA Champions League.
News of all that's transpired on and off the football field
Barcelona closed in on the LaLiga title as they picked up a 1-0 win over Osasuna and holders Real Madrid went down to
Borussia Dortmund missed a bagful of chances to draw 1-1 at home with Augsburg on Tuesday, as they squandered the opportunity to make up ground in the Bundesliga title race heading into the winter break.
IMAGES from the soccer matches played across European leagues on Friday.
A round-up of Saturday's action in La Liga and the Bundesliga.
Rediff.com brings you these and other exciting news from the week gone by in this photo feature...
Diego Costa's season is getting better and better. The Atletico striker found the net again and took the Madrid team atop the La Liga table.