The injury list in the La Liga keeps growing as the season progresses and this time Lionel Messi and Gareth Bale are the unfortunate victims...
Portugal international Goncalo Guedes fired Valencia into the lead in the 35th minute with a thumping shot from inside the area which was too powerful for Madrid goalkeeper Keylor Navas.
An insatiable Lionel Messi hit a hat-trick as Barcelona hammered Espanyol 5-0 in a local derby on Saturday to make it three wins from three and take full advantage after Liga champions Real Madrid were held to a 1-1 draw at home to Levante.
In other European football action Real Madrid were left frustrated after a goalless draw against Athletic Bilbao in their La Liga match on Sunday.
A round-up of Saturday's football action in La Liga, Bundesliga and Ligue 1.
Italy's top-flight Serie A soccer league launched a new anti-racism campaign on Monday by presenting artwork featuring three side-by-side paintings of apes but the move has been described by campaign group Fare as a sick joke. News of all that's transpired on and off the football field.
Substitute Sergio Araujo struck a late equaliser as Las Palmas held Real Madrid to a 2-2 draw and left them with a one-point lead over Barcelona at the top of La Liga on Saturday.
Juventus rehire Allegri.
Promoted Alaves dealt champions Barcelona a shock 2-1 defeat at the Nou Camp on Saturday while Cristiano Ronaldo returned from injury to help Real Madrid thrash Osasuna 5-2 and go two points clear at the top of La Liga. With Lionel Messi, Luis Suarez and Andres Iniesta on the bench, Barcelona went behind to the visitors in the 39th minute before Frenchman Jeremy Mathieu equalised in the 46th. Ibai Gomez then scored the winner in the 64th.
A late goal by Toni Kroos sealed victory as Real Madrid defeated an impressive Celta Vigo side 2-1 to win their first home La Liga game of the campaign on Saturday.
Arsenal manager Unai Emery was pleased with his team's first away clean sheet of the season.
It looks like Emmanuel Macron just got lucky again.
News of all that's transpired on and off the football field
Cristiano Ronaldo scored his 400th goal for Real Madrid as Zinedine Zidane's side closed in on a first La Liga title since 2012, easing to a 4-1 win over Sevilla on Sunday while Neymar hit a hat-trick for Barcelona, who thrashed Las Palmas 4-1.
The 25-year-old striker, who stands 1.76 metres tall, caught the eye on the big stage against Germany, driving home a penalty at the end of the first half before poking in the ball on 72 minutes following a rare blunder by Germany goalkeeper Manuel Neuer.
Didier Deschamps has let his hair go grey naturally since the last time he picked up a European title 16 years ago. The diminutive Deschamps was never a spectacular player -- a la Zinedine Zidane -- and certainly does not belong to the Jose Mourinho school of coaching with sensational sound bites. But the unglamorous Frenchman with the twangy voice has been instrumental in taking the host nation through to Sunday's Euro 2016 final against Portugal.
The Portuguese forward put his team on the verge of their third final in four years and took his tally to 103 goals in the competition as he helped Madrid vanquish their neighbours at the Santiago Bernabeu.
Tite was asked about reports that he was set to take charge of the Champions League winners during a news conference ahead of Sunday's friendly against Austria, although it was not clear where they had originated.
Real Madrid's teenage Brazilian duo Vinicius Junior and Rodrygo Goes sent them top of La Liga as both scored in a 2-0 win over Osasuna on Wednesday.
The Belgian forward came off the bench to make his Real debut in Saturday's 3-2 win over Levante, having had his start to life at the club hit by a thigh injury the day before the La Liga season began.
Liverpool came into Saturday's Champions League final against Real Madrid on a wave of confidence but Zinedine Zidane's side showed exactly why they are the masters of Europe's top club competition in their 3-1 win.
Real Madrid reached their 14th European Cup final and crushed Manchester City's hopes of a maiden title after Gareth Bale's deflected effort secured a 1-0 victory in the second leg of their Champions League last four clash on Wednesday.
Barcelona thrashed Sporting Gijon 6-1 to go top of La Liga on a dramatic night in Spain on Wednesday as Luis Enrique announced he was stepping down as the Catalan club's coach at the end of the season.
'The silky touch, the swerving runs, the parabola pass perfection, the goals -- Salah on a football pitch these days is a sporting experience so celestial you feel inebriated just witnessing it.' 'It is football of the gods: Pure, eye-popping and incomprehensible,' applauds Dhruv Munjal.
Liverpool thrashed Atalanta 5-0, Real Madrid boosted their chances of reaching the Champions League knockout stages with a 3-2 home victory over Inter Milan and Bayern Munich came from behind to crush RB Salzburg 6-2.
Barcelona defender Gerard Pique has decried the fans who booed manager Luis Enrique and the players in Sunday's laboured 2-1 home win over Leganes in La Liga as having a short-term memory.
Liverpool laboured to a 2-0 win over Denmark's Midtjylland on Tuesday as a goal from Diogo Jota and a Mohamed Salah penalty secured a hard-fought Champions League Group D victory at Anfield.
News of all that transpired on and off the football field.
Cristiano Ronaldo shrugged off the boos of his own supporters to fire Real Madrid to a 3-0 win over Real Sociedad on Sunday.
Meanwhile, Real Mallorca made a dream return to La Liga with a 2-1 victory over Eibar at the Estadi Son Moix on Saturday, less than two months after sealing back-to-back promotions to rejoin Spain's soccer elite.
Sergio Ramos made amends for his untimely own goal last week at Sevilla by scoring twice as Real Madrid bounced back from two successive defeats by beating Malaga 2-1 on Saturday to go four points clear at the top of La Liga.
Real Madrid dropped points for the third time in seven games since Zinedine Zidane's return as they were held to a 0-0 draw away to Getafe in La Liga on Thursday, which harmed their neighbours' hopes of a top-four finish.
Atletico Madrid maintained a two-point lead in La Liga with a 3-0 victory at Las Palmas and Barcelona and Real Madrid stayed hard on their heels with thumping wins over Athletic Bilbao and Sporting Gijon on Sunday.
News of all that transpired on and off the football field.
Barcelona's fourth defeat of the season left them seventh in the standings on 14 points after 10 games, 12 points behind leaders Atletico.
Real Madrid captain Sergio Ramos again came to his side's rescue as they snatched a dramatic 3-2 victory over Deportivo La Coruna on Saturday to keep Zinedine Zidane's side six points clear at the top of La Liga and set a club record 35 games unbeaten.
Teenager Curtis Jones grabbed a 58th-minute winner as an injury-hit Liverpool qualified for the knockout stage of the Champions League with a 1-0 win over Ajax Amsterdam at Anfield on Tuesday.
Set to start his stint as manager-cum-player of Chennaiyin FC, Italian World Cup winner Marco Materazzi promised to do his best to raise the profile of the game in the country through the Indian Super League which kicks off next month.
Summary of all that transpired on and off the football field
On Saturday he made the difference yet again with two goals to help Real Madrid secure a third Champions League title in four years as they crushed Juventus 4-1 in a riveting final.