Everton enjoyed their first Premier League win at Manchester United for 12 years despite playing virtually the entire game with 10 men.
Promoted Sunderland, who have defied expectations to stay in the top half of the Premier League table, could be the worst affected with six players going to the tournament, while the likes of Fulham, Manchester United, Burnley and Crystal Palace will also have to make do without some key personnel.
Manchester City's Erling Haaland became the fastest player to reach 100 Premier League goals to ignite their charge on Tuesday.
A late penalty from new signing Lukas Nmecha earned promoted Leeds United a hard-fought 1-0 victory over Everton in their first match back in the Premier League.
Manchester United's exiled forward Marcus Rashford has delivered a scathing assessment of the Premier League side's struggles
England midfielder Jack Grealish joined Everton on a season-long loan from Manchester City on Tuesday as he seeks to restart his stalled international career.
Fulham held visitors Manchester United to a 1-1 draw in the Premier League on Sunday.
Former Everton and Manchester United manager David Moyes has agreed to take over as head coach of Real Sociedad until 30 June 2016, the La Liga club announced on their website
Everton have signed David Moyes for a second spell as their manager, the Premier League club said on Saturday.
The latest figures have shown that Everton manager David Moyes is the best value-for-money as the football boss.
Liverpool continued their march towards the Premier League title with a 1-0 victory over Everton in a scrappy Merseyside derby as Diogo Jota slotted home the winner in the second half on Wednesday.
David Moyes, who has only been in charge of Manchester United since July, paid the price for a hugely disappointing season on Tuesday when it was announced that he has left the club.
Real Sociedad coach David Moyes praised his side's determined defending after their 1-0 victory over Barcelona.
Graham Potter is in talks to replace Lopetegui, according to British media reports, and the former Chelsea and Brighton & Hove Albion manager is expected to take charge of West Ham for their FA Cup third-round game at Aston Villa on Friday.
Arsenal snapped a season-long jinx against Newcastle United with a nervy 1-0 win in their last Premier League home game on Sunday.
IMAGES from the Premier League matches played on Saturday.
A round-up of Saturday's action in the Premier League.
A round-up of Saturday's action in the English Premier League.
A round-up of Saturday's action in the Premier League.
A round-up of Wednesday's action in the Premier League
Alex Ferguson may have been stripped of his Manchester United ambassadorial role last week but his legacy as manager remains a stifling cloud for those following in his footsteps, with Erik ten Hag the latest to be jettisoned after failing to measure up.
Champions Manchester City could only muster a 2-2 Premier League draw with Brighton & Hove Albion on Saturday.
Ruben Amorim is set to become the next manager of Manchester United with the Premier League club prepared to pay Sporting the 10 million euros ($10.79 million) release clause, the Portuguese club said on Tuesday.
Images from Saturday's action in the Premier League.
IMAGES from the Premier League matches played on Sunday
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Villa remain fourth on 56 points, three points above Spurs in fifth, having played a game more. West Ham are seventh on 44, three points behind sixth-placed Manchester United who have a game in hand.
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
A summary of Sunday's action in the Premier League.
Images from the Premier League matches played on Thursday
Tottenham Hotspur hammered 10-man Aston Villa 4-0 in the Premier League on Sunday thanks to four second-half goals, allowing them to close the gap with their Birmingham rivals to two points in the chase for Champions League football next season.
Arsenal had more than twice as many chances but failed to take any as the visitors defended gamely.
Jarrod Bowen and Mohammed Kudus' second-half goals gave West Ham a 2-0 win over Manchester United in the Premier League's early game on Saturday, as the Hammers briefly moved into the top six.
West Ham suffer Fabianski injury blow
West Ham United manager David Moyes and players Issa Diop and Josh Cullen have returned positive tests for COVID-19, the Premier League club said on Tuesday.
The government last month opened the door for elite sport to resume and the Premier League said it would restart its season on June 17.
Erik ten Hag will succeed interim boss Ralf Rangnick from next seaso
'I hope we will all look back and think: 'Maybe we were indulging too much'
Barcelona will face a struggling Galatasaray team who are 13th in the Turkish top-flight.
It's not Mourinho, reckons former defender Gary Neville