Southampton secured a 1-0 victory against Fulham with a late penalty, making them the first non-Premier League club to reach the FA Cup quarter-finals this season.
Arsenal maintained control of the Premier League title race as they chiselled out a nervy 2-1 win over London rivals Chelsea to open up a five-point lead at the top of the table on Sunday.
Manchester City's Erling Haaland achieved the feat in 111 games, 13 fewer than the previous fastest centurion Alan Shearer.
Arsenal's Premier League title prospects were enhanced without them even kicking a ball on Wednesday as their closest challengers Manchester City and Aston Villa both dropped points.
IMAGES from the EPL matches played on Sunday
IMAGES from the Premier League matches played on Sunday
Arsenal re-established their five-point lead at the top of the Premier League with a 2-0 home win against Brentford on Wednesday and for the second evening running the goals flowed as Aston Villa won 4-3 in a thriller at Brighton and Hove Albion.
Erling Haaland took his league tally this season to 11 in eight games with both goals in City's 2-0 home win over Everton -- a result that temporarily put City above Arsenal on goals scored.
Manchester City's Erling Haaland became the fastest player to reach 100 Premier League goals to ignite their charge on Tuesday.
Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
Fulham held visitors Manchester United to a 1-1 draw in the Premier League on Sunday.
A deflected late strike from Lisandro Martinez earned Manchester United a much-needed 1-0 victory at Fulham in the Premier League on Sunday.
Manchester City and Chelsea both secured their Champions League places with victories on the final day of the English Premier League season and Newcastle United joined them despite stumbling to a last-day defeat.
Images from Thursday's action in the Premier League.
IMAGES from the English Premier League matches played on Saturday.
Amad Diallo struck a late equaliser as Manchester United made a mockery of their recent form to hold Premier League leaders Liverpool
Images from Saturday's action in the Premier League.
Images from Saturday's FA Cup quarter-finals.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
IMAGES from the Premier League matches played on Sunday.
Arsenal closed the gap on leaders Liverpool with a 2-1 Premier League victory at Nottingham Forest
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
Arsenal were held to a 1-1 Premier League draw by London rivals Fulham on a grey wet Sunday at Craven Cottage as Raul Jimenez scored early for the hosts and William Saliba equalised for the visitors at the start of the second half.
Images from the English Premier League matches played on Sunday night.
All the action from soccer matches played in Europe on Monday.
IMAGES from the Premier League matches played on Saturday.
Harry Kane became Tottenham Hotspur's joint all-time record goal-scorer with the winner in his side's 1-0 victory at Fulham in the Premier League on Monday.
Vitaliy Mykolenko's 39th-minute own goal had put Luton ahead before Jack Harrison cheered the Everton faithful with an equaliser in the 55th minute, hammering in a low shot that Luton keeper Tim Krul allowed to let slip through his hands.
Chelsea's Joao Felix endured a nightmare debut when he was sent off in a 2-1 Premier League defeat at local rivals Fulham.
IMAGES from the Premier League matches played on Saturday
IMAGES from the English Premier League matches played on Saturday.
A controversial statue of the late pop star Michael Jackson will be removed from outside Fulham's Craven Cottage ground after fans complained it made the Premier League club look like a laughing stock.
Manchester City roared back to the top of the Premier League with a 6-1 thrashing of Bournemouth after Manchester United steadied the ship
Manchester United and Fulham served up a frantic 2-2 draw at Craven Cottage on Sunday while Newcastle United stunned Aston Villa 6-0 with a hat-trick from Andy Carroll on another dramatic day of Premier League action.
Kevin de Bruyne struck twice to inspire Manchester City to a dominant 4-2 win at Crystal Palace on Saturday and move the champions level on points with Liverpool at the top of the Premier League table.
Athletic Bilbao beat Barcelona 4-2 at home to knock them out of the Copa del Rey
Fulham's abject season reached a new low as third-tier Sheffield United snatched a last-gasp winner in extra time to dump the Premier League side out of the FA Cup 1-0 in a fourth round replay on Tuesday.
Tottenham Hotspur's Son Heung-min returned to form with two goals in his side's 3-0 defeat of second-tier Preston North End in the FA Cup fourth round and Casemiro also grabbed a brace in Manchester United's 3-1 win over Reading.
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Italy suffered a serious blow ahead of next month's World Cup when midfielder Riccardo Montolivo broke his leg during a warm-up game against Ireland at Craven Cottage on Saturday.