Liverpool will take on LASK, Union Saint-Gilloise and Toulouse in the Europa League group stage while debutants Brighton & Hove Albion will face Ajax Amsterdam and Olympique de Marseille following the draw on Friday.
Ruthless Arsenal threw down the gauntlet in the Premier League title race with a 5-0 thrashing of London rivals Chelsea to roar three points clear at the top of the table on Tuesday.
Champions Manchester City's 12-match winning streak in the Premier League came to an end as Julio Enciso's stunner earned sixth-placed Brighton and Hove Albion a 1-1 draw.
Manchester City moved four points clear of Arsenal atop the Premier League table with an 11th consecutive victory.
Images from the English Premier League matches played on Saturday, April 13.
The Englishman lasted 31 games, winning only 12, before the owners pulled the trigger.
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
A summary of Sunday's action in the English Premier League.
Rennes denied late Europa League equaliser due to little-known rule
Arsenal had more than twice as many chances but failed to take any as the visitors defended gamely.
Brighton secured their second victory of the competition with a comfortable win at Ajax thanks to goals from Ansu Fati and Simon Adingra.
Substitute Gabriel Martinelli fired a last-gasp winner to earn Arsenal a 1-0 victory over Manchester City on Sunday.
Vitaliy Mykolenko's 39th-minute own goal had put Luton ahead before Jack Harrison cheered the Everton faithful with an equaliser in the 55th minute, hammering in a low shot that Luton keeper Tim Krul allowed to let slip through his hands.
Manchester United manager Ralf Rangnick said the club had to ensure its players were vaccinated following a COVID-19 outbreak that led to the postponement of their last two Premier League games.
Images from the English Premier League matches played on Saturday
Arsenal returned to the top of the Premier League with a comfortable 2-0 victory over relegation-threatened Luton Town
Manchester City and Arsenal closed in on Premier League leaders Liverpool with contrasting victories on Saturday as Manchester United's bubble was burst by Fulham.
Images from the English Premier League matches played on Sunday night.
Liverpool will resume their quest for a first top-flight title in 30 years at city rivals Everton on June 21, as the English Premier League released its revised fixture list for the first three weeks of the restarted season on Friday. Liverpool are 25 points clear at the top and are two victories away from winning the Premier League, but will have a shot at securing the title by beating Everton if City lose to Arsenal.
IMAGES from the English Premier League matches played on Tuesday.
Brazilian Casemiro struck late to send Manchester United into the FA Cup quarter-finals with a 1-0 victory over Nottingham Forest as teenagers Jayden Danns and Lewis Koumas inspired Liverpool to a 3-0 win over Southampton on Wednesday.
IMAGES from the Premier League matches played on Saturday.
The schedule for the league's 2022-23 season was released with Liverpool starting away to promoted team Fulham. City plays its first game a day later.
Manchester City roared back to the top of the Premier League with a 6-1 thrashing of Bournemouth after Manchester United steadied the ship
IMAGES from the English Premier League matches played on Saturday.
Images from the English Premier League matches played on Sunday
Erik ten Hag's side, featuring several players who played in the World Cup in Qatar, could have doubled their lead when Anthony Martial's shot was well saved by Burnley goalkeeper Bailey Peacock-Farrell.
Chelsea came from behind to beat Crystal Palace 3-1 thanks to added time goals from Conor Gallagher and Enzo Fernandez.
Manchester City won an unprecedented fourth straight English top flight title with a 3-1 win over West Ham United.
IMAGES from the Premier League matches played on Saturday.
IMAGES from the Premier League matches played on Wednesday.
Addo joins Roberto Martinez (Belgium), Carlos Queiroz (Iran) and Gerardo Martino (Mexico) as coaches who immediately left their jobs after World Cup elimination this week.
Manchester City climbed back into the Premier League's top four as second-half goals by Phil Foden, Julian Alvarez and Bernardo Silva sealed a comeback 3-1 victory at Everton on Wednesday.
Woeful defending led to two Brighton goals in two first-half minutes as 34-year-old Glenn Murray and Shane Duffy outsmarted United's 117 million pound ($149.21 million) back four to demonstrate why manager Jose Mourinho had sought to upgrade it.
Potter joins Chelsea a day after they sacked Tuchel, with the team sixth in the league on 10 points after six matches.
Jose Mourinho's side top Group G with a maximum nine points, three clear of second-placed Slavia.
Images from the English Premier League matches played on Saturday night.
In Conte's absence, Stellini guided Spurs to wins over Manchester City, West Ham United and Chelsea.
English Premier League leaders Manchester City and Chelsea slugged out a magnificent 4-4 draw at Stamford Bridge.
Manchester United suffered an outbreak of COVID-19 among players and staff on Sunday, jeopardising their next Premier League game against Brentford.