Real Madrid suffered a shock 2-0 loss and finished with nine men against Celta Vigo in LaLiga on Sunday.
Nottingham Forest and Aston Villa reach the Europa League semi-finals, while Braga and Freiburg also advance in a dramatic night of European action.
A summary of Saturday's action in LaLiga, Serie A, Bundesliga and Ligue 1.
Barcelona stay on course to defend their Copa del Rey title with a 2-1 win over Albacete.
Napoli thrash Palermo to advance to Coppa Italia last 16
Lamine Yamal's second-half goal secured a 1-0 victory for Barcelona against Athletic Bilbao, extending their lead in La Liga.
Real Madrid squeezed past Atletico in a pulsating Madrid derby while Inter were held, keeping Serie A title race alive.
IMAGES from football matches played across European leagues on Saturday
Mbappe chasing Ronaldo record as Real Madrid host Celta
Barcelona closed the gap on their rivals Real Madrid, moving up to 28 points and pulling two clear of third-placed Villarreal.
An inspired Kylian Mbappe scored two fabulous goals to guide Real Madrid to a commanding 3-0 win at Athletic Bilbao on Wednesday, ending their three-game winless streak in LaLiga.
Sevilla knocked Barcelona off the top of the Primera Liga after goals from Frederic Kanoute and Adriano Correia earned a 2-0 home win over Osasuna on Sunday.
Spirited Rayo Vallecano hold Real Madrid to 0-0 draw
Atletico Madrid extended their unbeaten run in LaLiga to nine matches with a 2-0 victory over hosts Real Betis on Monday.
In Lille, substitute Olivier Giroud turned the game on its head in the 80th minute.
The return fixtures will be played on May 11 and the final in Stockholm on May 24.
Valencia's Paco Alcacer and Dani Parejo both hit doubles in a surprise 5-1 away thrashing of high-flying Celta Vigo in La Liga on Saturday.
On debut, substitute Marcus Rashford became the first Englishman to play a first-team game for Barcelona since former England striker Gary Lineker in 1989.
Lewandowski is the leading scorer in LaLiga this season with 25 goals, three more than Real Madrid's Kylian Mbappe.
Real Madrid manager Carlo Ancelotti said that he understands the club fans booying him and his team in their 5-2 win over Celta Vigo.
Spain face Ronald Koeman's Netherlands away on Thursday before returning home for the second-leg on March 23.
Brazilian teenage striker Endrick came off the bench to score two goals in extra time and help Real Madrid rescue a hard-fought 5-2 win over Celta Vigo.
Images from Sunday's action in LaLiga and Serie A.
A round-up of Saturday's action in LaLiga, Serie A and Ligue 1.
A round-up of Saturday's action in LaLiga, Ligue 1 and Serie A
A summary of Saturday's action in LaLiga, Bundesliga and Serie A.
Read Madrid midfielder Jude Bellingham has been suspended for two games by La Liga for showing contempt towards the referee having received a red card after the final whistle in their 2-2 draw with Valencia on Saturday.
Leverkusen's Schick scores hat-trick in comeback win over Heidenheim.
IMAGES from football matches played across Europe on Wednesday.
IMAGES from football matches played across Europe on Wednesday.
Barca will now visit seventh-placed Osasuna on Saturday before hosting Young Boys in the Champions League next week, when they will look to rebound following a 2-1 loss in their opening match at Monaco.
A Spanish court has handed soccer player Santi Mina a four-year prison sentence for sexually abusing a woman in the southern town of Mojacar in 2017
La Liga leaders Real Madrid cruised to a 4-0 home win over relegation-threatened Celta Vigo on Sunday to restore their seven-point lead at the top of the table with a dominant display.
Robert Lewandowski smashed home a rebound to earn Barcelona a 2-1 win against Athletic Bilbao in an absorbing LaLiga clash on Saturday.
All the action from football matches played in Europe on Wednesday
The Copa del Rey semi-final draw will be made on Friday.
Cristiano Ronaldo said there is no chance of him playing club football in Europe again and that the Saudi Arabian league is better than Major League Soccer.
IMAGES from the soccer matches played across leagues on Friday
Robert Lewandowski and Raphinha both scored twice to help Barcelona thrash hosts Villarreal 5-1.
Messi's contract with Barcelona is set to come to an end this season
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