New research using zebrafish suggests that changes in gene activity can lead to the hardening of spinal discs, a major cause of neck and back pain. The study identified potential drug targets, including existing osteoporosis medication and pathways related to fat and phosphate metabolism, offering new avenues for treating intervertebral disc degeneration (IVDD) beyond surgery.
A new study from The Rockefeller University reveals that short, intense sprints significantly alter a quarter of measured plasma proteins, far more than moderate exercise. These protein changes are linked to a lower risk of cardiovascular and metabolic diseases, including obesity and type 2 diabetes, and even slower biological aging. The findings suggest that high-intensity exercise triggers profound molecular adaptations crucial for health.
A recent study published in npj Aging reveals that epigenetic clocks, which estimate biological age by measuring DNA methylation, capture various aspects of aging biology, including immune system changes, metabolism, and cell communication. Researchers also developed new gene-expression-based clocks that show stronger predictive power for age-related diseases and mortality.
Scientists from Agharkar Research Institute (ARI), Pune, have developed a biodegradable nanocarrier platform for targeted gene therapy in breast cancer. This strategy uses mesoporous silica nanoparticles to deliver siRNA molecules, effectively inhibiting tumour growth and reducing off-target effects, offering a promising new approach to cancer treatment.
New research from the Revived Genomics of Personality Consortium, published in Nature, suggests that the genetics of personality, involving over 1,200 gene variants linked to the Big Five traits, are significantly associated with various life outcomes including health, education, and career paths. While individual gene variants have small effects, their combined impact is substantial, and environmental factors also play a crucial role in shaping personality.
A new study has identified a shared biological process that could explain chronic exhaustion in conditions like long Covid, PTSD, rheumatoid arthritis, chronic fatigue syndrome, and multiple sclerosis. Researchers found that despite different triggers, these illnesses converge on common biological systems, including immune and metabolic regulation, leading to profound fatigue. The findings suggest a deeper connection between these seemingly disparate disorders at a network level, rather than at an individual gene level.
From Virasat and Gardish to Tezz and Rangrezz, here's a look at Priyadarshan's serious side of Bollywood, ahead of his new movie Haiwaan.
Healthy muscles do much more than enable movement. They are essential for maintaining metabolism, regulating blood sugar levels and supporting overall health.
A new study suggests the mechanical load from the constant beating of the heart may suppress cancer cell growth, offering insights into why heart cancer is rare. Researchers found that cellular pathways in heart tissues alter gene regulation in cancer cells, preventing proliferation.
Creatine has become one of the most talked-about supplements in fitness circles. While many swear by it for improving strength and performance, others worry it could damage their kidneys, cause hair loss or lead to unhealthy weight gain.
Doctors and researchers are increasingly concerned about the potential link between exposure to polluted air during pregnancy and its influence on foetal development, particularly the male reproductive system. While hypospadias, a common congenital abnormality, is multifactorial, endocrine-disrupting chemicals in air pollution are being investigated for their role. Experts call for more research and advise expectant mothers on preventive measures.
A new study by King's College London and QIMR Berghofer Medical Research Institute has identified 74 genomic locations, including 39 new ones, linked to anxiety symptoms. Analysing data from nearly 700,000 people, the research highlights the complex interplay between genetics and environmental factors in anxiety development and offers new insights into its biological underpinnings.
'Control your A, B, C and D.' 'A is A1C, keep your A1C below 7 per cent.' 'B is blood pressure, so keep your blood pressure at 130/ 80 or at least below 140/ 90.' 'C is cholesterol. The bad cholesterol is the LDL cholesterol, and it should be kept below 100, preferably below 70 or 50.' 'D is discipline like diet, exercise, sleep, no smoking, etc.' 'People with diabetes who follow A, B, C and D can live up to even 100 years of age without any complications.'
A new study suggests a blood test called 'VeloCD' can predict the trajectory of an illness and how well a patient might respond to treatment by measuring key markers in the blood.
Scientists at IIT Mandi have identified the cellular signature of anaesthesia in plants, a discovery that challenges conventional understanding of consciousness. Their research shows plants respond to anaesthetics in a synchronised manner, reorganising cellular nuclei despite lacking a brain or nervous system, suggesting a more sentient nature than previously believed and resonating with ancient Indian philosophical thought.
NASA has announced three missions to the moon as part of efforts to establish a permanent base on the earth's natural satellite. The USD 20 billion plan includes lunar rovers and drones for experiments to help master skills to live and operate in the dangerous environment.
A new study reveals that neuron networks in the brain's hippocampus, the memory centre, become sparser but more structured and refined as animals mature.
To get real, long-lasting results, you need to understand what your skin needs, respect its limits and invest in habits that will last longer than trends, advises Dr Rupika Singh.
The 2024 Nobel Prize in physiology or medicine has been awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation.
Dr Arush Sabharwal, bariatric and metabolic surgeon at SCOD (Surgical Centre for Obesity and Diabetes) Clinic, explains how choosing certain foods can help boost your metabolism.
'If a parent was diagnosed at 50, the child should start screenings 5 to 10 years earlier (around 35 to 40).' 'Awareness of family history and age of onset helps catch the disease early.'
From tackling visa woes to admission counselling, rediffGURU Dr Karan Gupta helps you choose the right course and country to study abroad.
A stressful workplace may dramatically change gene expression in your immune system and significantly impact your health, a new study suggests.
A stressful workplace may dramatically change gene expression in your immune system and significantly impact your health, a new study suggests.
Uttar Pradesh Chief Minister Yogi Adityanath accused Opposition parties of trying to divide society, drawing a parallel between the violence against religious minorities in Bangladesh and historical events in Ayodhya and Sambhal. He criticized those who indulge in caste-based politics and said they are responsible for the current situation. Adityanath's comments come amid widespread violence against religious minorities in Bangladesh following the toppling of the Sheikh Hasina government.
'Obesity is a raging conversation globally now, and manufacturing of generics will pick up after the patent expires.'
'Making sure that you're getting enough sleep, that your weight is maintained correctly and you exercise regularly.'
'Thirty per cent of the world's deaths in young people, due to heart disease, are encountered by people in India.'
Treatment for arthritis is mainly focused on symptom management and slowing the progression of the disease, says Dr Vishal Shinde.
The city's 24-hour Air Quality Index, recorded at 4 pm every day, stood at 418, up from 334 the previous day, and it may trigger stringent restrictions under the third stage of the graded response action plan to mitigate hazardous conditions.
'It is admitted that the AZ vaccine can, in very rare cases, cause TTS.'
Svante Paabo has established an entirely new scientific discipline, paleogenomics. By revealing genetic differences that distinguish all living humans from extinct hominins, his discoveries provide the basis for exploring what makes us uniquely human.
Signalling pathways are complicated chain reactions which control many important human biological processes and in which certain proteins act as messenger molecules that promote or block the signals of other proteins.
Along with persistent cough that may last for several weeks, tuberculosis patients also complain of frequent bouts of fever, chills and sweating at night, says Dr Rahul Kendre.
The World Health Organisation on Monday warned that the global risk from the Omicron variant is "very high" based on early evidence, saying the mutated coronavirus could lead to surges with "severe consequences."
He further said that only a marginally high proportion of COVID-19 patients are of younger age and that the average of patients in the first wave was 50 years and in this wave, it is 49 years. He also said that the older population continues to be more vulnerable to be admitted in the hospital in the current wave.
Moody's on Thursday upped India's growth projection for the next financial year beginning April 1, to 13.7 per cent, from 10.8 per cent estimated earlier, on the back of normalisation of activity and growing confidence in the market with the rollout of COVID-19 vaccine. For current fiscal, the US-based rating agency expects the economy to contract 7 per cent, lower than its previous estimate of 10.6 per cent contraction.
As per a new study, people who were physically active were less likely to experience a new episode of depression.
"The COVID-19 cases are rising, but hospitalization and deaths are still less," said sources.
