Bologna advanced to the Europa League quarter-finals after a thrilling 4-3 win against AS Roma.
Aston Villa secured a 1-0 victory against Lille in the Europa League, while other matches saw Bologna draw with AS Roma and Porto win against VfB Stuttgart.
Lyon sealed top spot in the Europa League standings while Roma survived a red-card scare to reach the last 16 on a chaotic final league-phase night.
Francisco Moura's second-half strike earned hosts Porto a 1-1 draw against 10-man AS Roma in the first leg of their Europa League knockout round play-off on Thursday.
'RIP Diogo. Condolences to his family and friends during this incredibly sad time,' former Liverpool captain Steven Gerrard posted.
AS Roma secured their place in the Europa League last 16 with a 3-2 home win over 10-man Porto on Thursday thanks to a Paulo Dybala double, advancing 4-3 on aggregate.
IMAGES from the UEFA Champions League matches played on Wednesday
Lionel Messi drew vast crowds and showed flashes of his brilliance when his Inter Miami side were held to a goalless draw by African giants Al-Ahly as the revamped Club World Cup got off to a festive start on Saturday.
PSG beat Seattle to reach knockout stage at Club World Cup
In an early match, Norwegian side Bodo/Glimt secured a 3-2 home victory against FC Porto thanks to a brace from Jens Petter Hauge, despite going down to 10 men in the 51st minute.
Fans allowed for the mega final as UEFA said that each club would receive 6,000 tickets which are expected to go on sale from today, May 13. The final capacity for the match has yet to be confirmed.
The following is the draw for the Champions League last 16 which was held in Nyon on Monday:
IMAGES from the Europa League matches played on Thursday
Carrying a red floral wreath bearing his shirt number, Diogo Jota's Liverpool teammates joined relatives and residents in a small Portuguese town on Saturday for the funeral of the soccer star.
Leaders Porto suffered a shock 2-1 defeat at Famalicao as Portugal's Primeira Liga became the latest league to return to action following the coronavirus stoppage on Wednesday.
Atletico Madrid have moved to strengthen their forward line for next season following the exit of Mario Mandzukic by agreeing to buy Colombia striker Jackson Martinez from Porto.
Images from football matches played in Italy and Portugal on Sunday.
IMAGES from Champions League matches played on Wednesday.
A round-up of Wednesday's action in the UEFA Champions League.
Photos from the Champions League matches played across Europe on Tuesday
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Holders FC Barcelona have been placed in Group E, along with Bayer Leverkusen, AS Roma, Dinamo Zagreb.
IMAGES from the Champions League matches played on Wednesday
Barcelona took a big step towards the Champions League semi-finals.
Erling Haaland became the third player in Champions League history to score five goals in a game as he led Manchester City to an unrelenting 7-0 rout of RB Leipzig in the second leg of their last-16 tie.
'Porto are a really, really good football team. We have to play at our limit 100 percent'
Norma Godinho challenges sporting know-it-alls.
Jose Mourinho's Chelsea turned from domestic whipping boys back to European stalwarts on Wednesday, beating his former club Porto 2-0 to top Champions League Group G.
Defiant 10-man Porto upset Juventus to reach the Champions League quarter-finals on away goals after a 4-4 aggregate draw despite losing 3-2 to the Italians following extra time in a thrilling clash that went to the wire on Tuesday.
Tottenham Hotspur reached the semi-finals of the Champions League on away goals after a 4-3 (aggregate 4-4) defeat to Manchester City in a breathtaking quarter-final second leg game on Wednesday.
Jose Mourinho suffered a nightmare homecoming as Porto, the club he led to the Champions League title in 2004, inflicted a 2-1 defeat on his woefully out-of-sorts Chelsea side in Group G on Tuesday.
Manchester United beat Porto 1-0 while Arsenal trounced Villarreal 3-0 in second leg quarter-final matches in the Champions League to make the grade.
Images from the UEFA Champions League matches played on Tuesday
Real Madrid failed to win their Champions League group for the first time in four years when a late goal by substitute Marco Reus allowed Borussia Dortmund to equalise and clinch a 2-2 draw.
The wife of Spain's World Cup-winning captain Iker Casillas, Sara Carbonero, has announced that she has undergone surgery for cancer just three weeks after the goalkeeper suffered a heart attack.
AS Roma suffered another European humiliation on Tuesday when they had two players sent off, lost 3-0 at home to Porto and missed out on the Champions League group stage.
The win leaves United in 15th place in the Europa League standings on six points from four games.
Ruben Amorim is set to become the next manager of Manchester United with the Premier League club prepared to pay Sporting the 10 million euros ($10.79 million) release clause, the Portuguese club said on Tuesday.
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Ajax, semi-finalists last season, came from behind to beat PAOK 3-2 for a 5-4 aggregate win over the Greeks while Red Star knocked out FC Copenhagen on penalties after a bizarre shootout involving 22 spot-kicks.