While several top seeds will have their say, a look at some emerging players who could be serious contenders.
French Open champion Rafael Nadal has said he nearly ended his season after being forced to withdraw from the Indian Wells semi-finals with a knee injury in March.
Images from Day 3 of the French Open matches played at Roland Garros on Tuesday
Marie Bouzkova has withdrawn from the French Open before her second-round match after she reported that she has tested positive for COVID-19
Zverev twisted his ankle as he tried to retrieve a shot in the 12th game of the second set
Wawrinka won the Australian Open in 2014, the French Open in 2015 and the US Open in 2016. He is a 16-time winner on the ATP Tour.
Ons Jabeur stands on the verge of history with a maiden Grand Slam title at Wimbledon within her grasp but in Czech surprise package Marketa Vondrousova she faces a final opponent who could tear up the script and prolong her wait.
The two great rivals meet at Roland Garros for the first time in eight years in Friday's tie.
Factbox on Romanian Simona Halep, who beat Sloane Stephens 3-6, 6-4, 6-1 to win the French Open title on Saturday:
It wasn't just the tennis that amazed audiences at Roland Garros.
An FFT statement said it had consulted with the ATP, WTA and International Tennis Federation (ITF) to allow the Roland-Garros showpiece the benefit of an extra week.
Stefanos Tsitsipas moved into the Australian Open final on Friday, taking a step towards becoming the first Greek world number on.
Five top contenders for the women's title at the French Open, which starts on Sunday.
Novak Djokovic marched into the semis of the Dubai Tennis Championship, with a comfortable win over Hubert Hurkacz.
With no standout favourite in the women's field, it could provide an ideal stage for American Serena Williams to finally end her quest for an elusive 24th Grand Slam title.
Roland Garros has always been his favourite Grand Slam venue but he knows he will face an uphill task their on its claycourt surface in a tournament he has yet to win.
A frustrated Coco Gauff broke down in tears after her 7-5, 6-3 defeat by Jelena Ostapenko at the Australian Open on Sunday.
Rafael Nadal is hunting a record-extending and almost unbelievable 12th Roland Garros title is remarkable in itself.
Halep had clinched the French Open in 2018 after defeating American Sloane Stephens in the final.
Nadal said the two-week gap between the French Open and Wimbledon was not enough time for him to recuperate
Factbox on Rafael Nadal, who beat Novak Djokovic 6-0, 6-2, 7-5 on Sunday to win a record-extending 13th French Open title:
Images from Day 13 of the French Open, at Roland Garros, in Paris.
The five top contenders for the women's title at the Australian Open, which starts on Monday.
IMAGES from Day 8 of the French Open, at Roland Garros, on Sunday.
Rafael Nadal warmed up for the French Open with a battling 7-5, 1-6, 6-3 win over world number one Novak Djokovic as the Spaniard claimed a record-extending 10th Italian Open title in Rome on Sunday in the latest chapter of their rivalry.
Venus Williams is a two-time mixed doubles winner at Grand Slams, triumphing at the Australian Open and Roland Garros in 1998.
Caroline Garcia and Kristina Mladenovic recovered from a set down to beat Americans Coco Gauff and Jessica Pegula
The 13-time French Open champion is chasing a record-extending 22nd men's Grand Slam title. But time may be running out for Rafa who has been suffering from a chronic foot injury that had put his participation at the clay court major in doubt.
The 20-year-old is on the longest unbeaten run in the women's tour since Serena Williams bagged 34 victories in succession in 2013.
Herbert and Mahut added to their 2018 French Open title after recovering from a shaky start.
Novak Djokovic claimed a record-breaking 23rd men's singles Grand Slam title when he beat Norway's Casper Ruud 7-6(1) 6-3 7-5 in the French Open final.
IMAGES from Day 10 of the French Open at Roland Garros in Paris on Tuesday.
Most importantly, and most prominently, is the name of Serena's three-year-old daughter Olympia.
Images from the women's singles final at the French Open, in Paris, on Saturday.
It was only 13-time champion Rafael Nadal's third defeat here since his debut in 2005 and the first time in 115 best-of-five-set matches on clay that he had lost after taking the opening set.
Images from Day 7 of the 2022 French Open at Roland Garros in Paris on Saturday.
Images from Day 6 at the French Open, at Roland Garros, in Paris, on Friday.
Stefanos Tsitsipas enjoyed an incident-free path into the third round of the French Open with a win over Roberto Carballes Baena.
IMAGES from Day 5 of the French Open at Roland Garros in Paris on Thursday.
Fourth-ranked Carlos Alcaraz and Norway's world number seven Casper Ruud also have a shot at top spot.
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