Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
A makeshift United defence that included Casemiro at centre-back was easily picked apart by Palace on several occasions
Images from the Premier League match between Nottingham Forest and Crystal Palace at Selhurst Park, London, on Monday.
Images from the FA Cup semi-final between Crystal Palace and Aston Villa at Wembley stadium, London, on Saturday.
Crystal Palace forward Jean-Philippe Mateta was taken to hospital with a head injury after a collision with Millwall goalkeeper Liam Roberts.
Images from Saturday's FA Cup quarter-finals.
Crystal Palace's Eberechi Eze sparked a massive south London party by scoring the only goal to win the FA Cup 1-0 against Manchester City on Saturday and claim the club's first major trophy in their history.
Newcastle United thumped Crystal Palace 5-0 at St James' Park on Wednesday to go third in the Premier League table with a sixth consecutive win in all competitions as Jacob Murphy scored one goal and set up another.
Arsenal produced a scintillating display of attacking football to crush Crystal Palace 5-1.
Crystal Palace have never won the FA Cup, Aston Villa last lifted the trophy in 1957 and Nottingham Forest have not managed it since 1959 but all three clubs go into this weekend's semi-finals genuinely believing this could be their year.
Manchester City kept the pressure on Premier League leaders Arsenal with a comfortable 3-0 win over Crystal Palace on Wednesday, trimming the gap at the top of the table to two points as the title race sprints towards its conclusion.
West Ham draw 0-0 with Crystal Palace to stay just above the relegation zone, while Wolves are officially relegated from the Premier League after a poor season.
Michael Olise scored a stoppage-time penalty as Crystal Palace clawed back from two goals down to draw 2-2 with Manchester City in the Premier League at the Etihad Stadium on Saturday.
Alan Pardew has left Newcastle United to become manager of Premier League rivals Crystal Palace, the clubs confirmed on Saturday.
CrystalPalace forward Connor Wickham has been handed a three-match ban for elbowing Tottenham Hotspur's Belgium defender Jan Vertonghen in last weekend's Premier League game, the FA said on Friday.
Arsenal cleared arguably the most dangerous remaining obstacle in their path to the Premier League title by the skin of their teeth as Leandro Trossard's late goal secured a dramatic 1-0 win at West Ham United to restore their five-point lead on Sunday.
Arsenal edged past Crystal Palace on penalties on Tuesday to reach the semi-finals of the League Cup.
'We don't want artificial means of deciding who wins the league, who gets into the Champions League, who gets relegated and promoted.'
Non-league Macclesfield produced perhaps the FA Cup's greatest upset on Saturday when they beat holders Crystal Palace 2-1 in a thirdround thriller, knocking Oliver Glasner's team out of the competition and sending the Moss Rose crowd into raptures.
Media reports said former England manager Roy Hodgson was in line to replace De Boer at Selhurst Park.
Liverpool edged closer to Champions League qualification with a 3-1 victory over Crystal Palace at Anfield on Saturday, but the result came with a sour note as Mohamed Salah went off with a suspected hamstring injury.
Aston Villa skipper Stilian Petrov headed an equaliser three minutes from time to force a 2-2 draw at Championship side Crystal Palace in an outstanding FA Cup fifth round tie Sunday.
Robin van Persie and Wayne Rooney were on target as Manchester United secured a 2-0 home win over 10-man CrystalPalace on Saturday with a workmanlike display that will have done little to worry their Premier League title rivals.
Liverpool forward Mohamed Salah will miss the crunch clash against Manchester United due to injury, but manager Arne Slot confirms his return before season end.
Chelsea clinched their first Premier League title for five years with a 1-0 victory against Crystal Palace at a jubilant Stamford Bridge on Sunday.
Mikel Arteta insists the Premier League title race "starts again" after Arsenal's 2-1 loss to Manchester City, with five games left and everything still to play for.
Chelsea kept up their pursuit of the Premier League's top three clubs with a 1-0 win away to London rivals Crystal Palace on Sunday, thanks to a strike by N'Golo Kante early in the second half.
Mikel Arteta scored Premier League leaders Arsenal's first goal in a 2-0 win over Crystal Palace on Saturday but was later sent off in the early kickoff in south London.
Second-tier side Crystal Palace stunned Premier League champions Manchester United to win 2-1 after extra time in their League Cup quarter-final at Old Trafford on Wednesday and set up a semi-final against Cardiff City in January.
Crystal Palace beat Premier League champions Liverpool 3-2 on penalties to win the Community Shield after an entertaining 2-2 draw at Wembley on Sunday.
IMAGES from the EPL matches played on Sunday
Wolverhampton Wanderers and Sunderland have condemned the racial abuse directed at their players on social media following recent Premier League defeats.
Brentford scraped into the FA Cup fifth round with a narrow 1-0 win over sixth-tier Macclesfield, sealed by Sam Heathcote's second-half own goal after a spirited display from the hosts.
Liam Rosenior hailed 18-year-old Estevao's impact as Chelsea sealed their third straight win with a 3-1 victory over Crystal Palace.
Man City snatch chaotic 2-1 win at Liverpool to stay on Arsenal's heels
Liverpool striker Christian Benteke is having a medical before completing his move to Crystal Palace, the London club's manager Alan Pardew said on Friday.
Alan Pardew's dream of reprising a celebrated 25-year-old FA Cup triumph was scuppered by Liverpool as the seven-times champions came from behind to book a place in the quarter-finals with a 2-1 win at Crystal Palace on Saturday. This year's shock-laden competition had continued with second-tier Blackburn Rovers' 4-1 thrashing of the Premier League's Stoke City.
Assam Chief Minister Himanta Biswa Sarma received a signed Lionel Messi jersey and expressed his excitement on social media.
'I don't think that's fair, because we have other competitions as well we have to try to accommodate.'
Andy Robertson scored once and set up Mohamed Salah as Liverpool beat Wolves 3-1 at Molineux to reach the FA Cup quarter-finals, while Tottenham Hotspur's Premier League woes deepened after a 3-1 home defeat to Crystal Palace, extending their winless run to 11 matches.