There are at least seven major variants of coronavirus, including B.1.617 and B.1.351 (Beta), in Varanasi and its adjoining areas, according to a study conducted by the Banaras Hindu University and the Centre for Cellular and Molecular Biology (CCMB).
The Indian SARS-CoV-2 Genomics Consortium is closely tracking the new variant of COVID-19 called B.1.1.529 and its presence has not been detected in the country yet, officials said on Friday.
Covaxin, a whole-virion inactivated SARS-CoV-2 vaccine used for mass immunization in the country, showed a 65.2 per cent protection against the Delta variant in a double-blind, randomized, multicentre, phase 3 clinical trial.
Anurag Agrawal, the Director of the Institute of Genomics and Integrative Biology, said the study on effectiveness of the available vaccines on the B.1.617 variant of SARS-CoV2 suggests that post vaccination, the infections are milder.
The WHO said that studies have highlighted that the spread of the second wave has been much faster than the first in India.
The WHO's move came nearly three weeks after India objected to the B.1.617 mutant of the novel coronavirus being termed an 'Indian Variant' in media reports with the Union Health Ministry pointing out that the UN's top health organ has not used the word 'Indian' for this strain in its document.
"A recent risk assessment of the situation in India conducted by WHO found that resurgence and acceleration of COVID-19 transmission in India had several potential contributing factors, including increase in the proportion of cases of SARS-CoV-2 variants with potentially increased transmissibility; several religious and political mass gathering events which increased social mixing; and, under use of and reduced adherence to public health and social measures. The exact contributions of these each of these factors on increased transmission in India are not well understood," it said.
The WHO has countries to enhance surveillance and sequencing efforts to better understand circulating SARS-CoV-2 variants, submit complete genome sequences and associated metadata to a publicly available database.
Senior virologist Shahid Jameel on Sunday resigned as the chairman of scientific advisory group of Indian SARS-CoV-2 Genomics Consortium, a forum set up by union government in December last year for laboratory and epidemiological surveillance of circulating strains of COVID-19 in India.
The B.1.617 variant of SARS-CoV2, also being called a 'double mutant' or the 'Indian strain', has been found prevalent largely in Maharashtra and Delhi that have been severely hit by a devastating second wave of the pandemic.
The US is 'putting every ounce of its energy' to eliminate the long visa wait time in India, including sending a cadre of consular officers to the country and opening up its other overseas embassies as far away as Germany and Thailand for Indian visa applicants, according to a senior US visa officer. India was one of the very few countries where applications for US visas saw a major upswing after coronavirus-related travel restrictions were lifted. There have been growing concerns in India over the long waiting period for first time visa applicants, especially for those applying under B1 (business) and B2 (tourist) categories.
India will open their campaign in the T20 World Cup with a high-profile clash against Pakistan in Dubai on October 24, the International Cricket Council said on Tuesday.
The South African authorities said the detected cases and percentage of people testing positive are both increasing quickly, particularly in particularly in most populated province of Gauteng, North West and Limpopo regions of the country.
Images from the IPL 2023 match between Lucknow Super Giants and Delhi Capitals in Lucknow on Saturday.
The Centre had on Thursday asked all states and union territories to conduct rigorous screening and testing of all international travellers coming from or transiting through South Africa, Hong Kong and Botswana, where the B.1.1.529 variant has been detected.
The move came soon after Belgium confirmed a case of the B.1.1.529 variant in someone who had travelled back from Egypt earlier this month, with the European Union (EU) member states agreeing to a snap travel ban on seven African nations.
The study also shows that levels of these antibodies that are able to recognise and fight the virus are lower with increasing age, and that levels decline over time, providing additional evidence in support of plans to deliver a booster dose to vulnerable people.
A nine-year-old lioness Neela and a male lion named Pathbanathan, aged 12 years, succumbed to COVID-19 earlier this month.
However, the "good news" is that the US vaccines are effective against the Delta variant, said Fauci, the head of the National Institutes of Allergy and Infectious Diseases.
The new lineage called B.1.618 is distinct from the B.1.617, also known as the 'double mutant' virus that contains two mutations, E484Q and L245R, and is believed to be behind the powerful second COVID-19 wave sweeping through India.
Mortality rates were 0.7 per cent for Delta, 0.4 per cent for the original Omicron variant and 0.3 per cent for Omicron BA.2.
The study, which was conducted on more than 100 healthcare workers at three centres in India including Sir Ganga Ram Hospital, found that the B.1.617.2 Delta variant not only dominates vaccine-breakthrough infections with higher respiratory viral loads compared to non-Delta infections (Ct value of 16.5 versus 19) but also generates greater transmission among the fully vaccinated HCWs.
The rapid surge in cases during Delhi's fourth COVID-19 wave was mainly driven by the Delta variant, which likely has immune-evasion properties and counted for 60 per cent of the cases in April, according to a new study.
The UK's health authorities have confirmed that a new and "most significant" variant of COVID-19 is officially under investigation in the country as the government on Friday added six countries to its travel ban red list from southern Africa, where B.1.1.529 strain was first identified.
Vaccines Covishield and Covaxin work against SARS-CoV-2 variants Alpha, Beta, Gamma and Delta, while effectiveness tests against the Delta Plus variant is ongoing, the government said.
Namibia needed 20 runs from the last two overs, but Zahoor Khan came up with a perfect penultimate over and conceded just six runs, cleverly mixing up his deliveries and bowling with cross-seam.
The State Department has proposed not to issue temporary business visas for H-1B speciality occupations which allowed several companies to send their technology professionals for a short stay to complete jobs on site in the US, a move which could affect hundreds of Indians. The proposal, if finalised, will eliminate any misconception that the "B-1 in lieu of H policy" provides an alternative avenue for foreign professionals to enter the US to perform skilled labour that allows, and potentially even encourages them and their employers to circumvent the restrictions and requirements relating to the H non-immigrant classification established by Congress to protect the US workers, the State Department said.
The Covid-19 vaccine demonstrated an overall 90.4 per cent efficacy in phase 3 clinical trials, reports Sohini Das
"Protocol is very clear. Once any international traveller test positive, apart from following the routine protocol of containment and treatment, we are sending their samples to genome sequencing," said Mallikarjuna.
The double mutant variant, also known as B.1.617, is mostly dominating Maharashtra (761), West Bengal (124), Delhi (107) and Gujarat (102).
The Delta Plus variant have been detected sporadically in Maharashtra, Kerala and MP.
The recent spate of technical glitches in aircraft has prompted the Directorate General of Civil Aviation (DGCA) to issue an order on July 18, making aircraft maintenance engineers (AMEs) with category B1/B2 licences the final authorities in certifying planes. This has put the spotlight on the availability of such personnel. According to the order, airlines were resorting to frequent one-off authorisation by the Category A certifying staff at transit stations, which is not in line with existing regulatory provisions.
Mu -- also known by its scientific name as B.1.621 -- was first identified in Colombia in January 2021, and since then, there have been 'sporadic reports' of cases and some larger outbreaks in South America and Europe, the United Nations health agency said in its weekly bulletin on the pandemic on Tuesday.
According to the NCDC, 415 cases of the UK strain of coronavirus were found in genomes sequenced in Delhi, followed by 23 cases of the South African strain.
'We should hope that things are not as bad as in the United Kingdom'
It was on January 30, 2020 when a third-year medical student from Wuhan university tested positive for coronavirus, becoming the country's first COVID-19 patient, days after she had returned home following semester holidays.
The B.1.640.2 variant has been reported by researchers at institute IHU Mediterranee Infection in at least 12 cases, and has been linked to travel to African country Cameroon.
The Securities and Exchange Board of India (Sebi) has just released a proposal to alter the regulations pertaining to the sponsor system for mutual funds. One of the reasons for the proposed changes is that there are two conflicting regulations that need to be clarified. The other reason is that the sponsor system may itself be outdated as it stands, and the proposed changes would allow new entities such as private equity funds and portfolio management services to enter this space.
'Antiviral treatment will have no change. Spike protein change may affect the immunity protection.'
This apart, to further increase capacities, Bharat Biotech has partnered with Indian Immunologicals (IIL) to manufacture the drug substance for Covaxin. The technology transfer process is underway and IIL has the 'capabilities and expertise' to manufacture the inactivated viral vaccines at commercial scale.
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