Next up for the 35-year-old will be another American in 39th-ranked Tommy Paul with a potential semi-final clash against top-seeded Russian Daniil Medvedev, who he defeated in the Australian Open final from a two-sets deficit.
A former top-ranked junior, Nick Kyrgios' talent was never in question but the 27-year-old said that he felt his "ship had sailed" when it came to having deep runs at Grand Slams.
Novak Djokovic said he was "sad and empty" after a being disqualified from the US Open on Sunday after hitting a line judge in the throat with a ball during his fourth-round match against Spain's Pablo Carreno Busta.
Novak Djokovic survived a scare at the French Open to beat unseeded Argentine Diego Schwartzman in five sets.
Australian government officials have said unvaccinated players will be barred from the tournament in January, casting doubt on whether men's world number one and reigning champion Novak Djokovic will defend his title.
Novak Djokovic is prepared to miss the French Open and Wimbledon if COVID-19 vaccination becomes mandatory at the Grand Slams but he is not against inoculation, the world number one tennis player said.
Ace British tennis player Andy Murray ended his 2016 campaign on a perfect note after defeating Novak Djokovic in straights in the summit clash of the ATP World Tour Finals, assuming the mantle of year-end No. 1 in the Emirates ATP Rankings. Murray dethroned Djokovic 6-3, 6-4 in a contest that lasted for an hour and 43 minutes to earn his first title at the ATP finals and make sure he remained No. 1 until next season. Rediff.com takes a look at the hosts of celebrities from footballers, tennis champions and Hollywood stars, who attended this big clash.
Djokovic will need to win in Tokyo and then the US Open later this year to achieve the feat that has so far only been accomplished by Steffi Graf in 1988.
Alexander Zverev continued to rebuild his confidence on clay with a straight sets win over Spain's Roberto Bautista Agut in the Monte Carlo Masters second round.
The decision to lift the ban was met with protest from Ukraine, whose Foreign Minister Dmytro Kuleba said it was "immoral" and urged Britain to deny Russian and Belarusian players visas.
Novak Djokovic reached the semi-finals of the Australian Open on Wednesday after Kei Nishikori retired hurt when trailing 6-1, 4-1 in their quarter-final.
After a dominant start, Djokovic struggled in the second set and lost his temper even after closing it out.
Kazahk Bublik powers past Zverev in straight sets to reach Halle final
The 33-year-old, a record eight-time winner on the Melbourne Park Arena, slipped during the third set of Friday's third-round match against Taylor Fritz and disappeared off Rod Laver Arena for treatment.
World No 1 tennis player Novak Djokovic and wife Jelena Ristic were blessed with a baby boy early on Wednesday.
Thiem, the fourth seed, was leading 3-1 in the third set on Friday when the semi-final was interrupted by rain and then surprisingly abandoned for the day.
Carlos Alcaraz crashed to a humbling 6-3 7-6(4) defeat by Hungarian qualifier Fabian Marozsan in the third round of the Italian Open.
Austrian Thiem was 6-2, 3-6, 7-5, 5-7, 4-1 up when the men's match, which had already been halted on Friday because of bad weather, was stopped.
Novak Djokovic had hoped to have the crowd behind him as he began his bid to win the US Open and complete the calendar-year Grand Slam, but the Serb said the atmosphere was "not ideal" as Flushing Meadows fans roared on his underdog opponent.
World No. 1 Novak Djokovic remained at the top of the rankings chart
Djokovic remained unflustered despite dropping the opening set and suffering several tumbles on the greasy surface.
Tiley denies reports Djokovic will sue Tennis Australia
Roger Federer will make his return to the tennis circuit from a double knee surgery at an ATP 250 tournament in Qatar in March, having not played since last year's Australian Open.
Some 25,000-30,000 fans will be admitted to Melbourne Park on each day of the Grand Slam and Novak Djokovic got a taste of what was to come when he played an exhibition match in Adelaide after coming out of quarantine on Friday.
Three-time US Open champion Djokovic, who comes into the tournament having won his fifth Wimbledon title, is followed in the seedings by 2017 winner Rafael Nadal.
World number two Aryna Sabalenka will not play at the Indian Wells tournament after testing positive for COVID-19, the 23-year-old said.
This happened when both players were locked at 2-2 in the second set and Djokovic seemed to have enjoyed the unscheduled break...
Images from Day 3 of the US Open, at Flushing Meadows, New York.
Novak Djokovic ruthlessly took Matteo Berrettini apart at the ATP Finals on Sunday as he began his quest to reclaim the number one ranking by winning his opening group match 6-2, 6-1.
Nadal has traditionally started his French Open campaigns with at least one claycourt title under his belt but this year got to the French capital empty-handed.
Immigration Minister Alex Hawke is weighing exercising his discretionary powers to revoke Djokovic's visa
An Australian court upheld a government decision to cancel Novak Djokovic's visa on Sunday, ending the unvaccinated tennis superstar's hopes of winning the Australian Open and racking up a record-breaking 21 men's Grand Slam titles.
Nadal said the two-week gap between the French Open and Wimbledon was not enough time for him to recuperate
Tennis titans Rafael Nadal and Novak Djokovic met with Thai Prime Minister Prayuth Chan-ocha on Friday and visited the site of a deadly Bangkok bomb blast.
Djokovic, who is seeking to win a record 21st Grand Slam title at the tournament this month, said in a legal challenge on Saturday that he had been given the medical exemption because he had contracted COVID-19 last month.
'If I stayed home, I would feel guilt. I was born here, my grandparents are buried here, and I would like to have a history to tell to my kids.'
World number one Novak Djokovic said his win over Rafa Nadal in Friday's epic French Open semi-final was one of the top three matches he had played and he would remember it forever.
"(Novak) has said that he views this as a private matter for him. We would love to see Novak here, he knows that he'll have to be vaccinated to play here."
Australia's Nick Kyrgios said he supported vaccination "but how we are handling Novak's situation is bad, really bad". The Australian Open begins on January 17, but the multi-millionaire Djokovic is constrained from training as he sits in a hotel where one Iranian detainee said he had found maggots and mould in the bread.