Medvedev suffered a jarring early exit from the Canadian Masters last week but overcame some initial problems in a tricky tie against Shapovalov to edge both sets and book a meeting with American Fritz.
Grit, determination, nerves were all on show at the US Open final.
Images from Day 7 of the 2021 US Open in New York on Sunday.
Venus Williams will miss the upcoming US Open due to an injury, becoming the third U.S. female after her sister Serena and Sofia Kenin to announce on Wednesday they would not take part in the final Grand Slam tournament of the year.
Iga Swiatek, Aryna Sabalenka and Coco Gauff, are a handful of contenders ready to swoop in
IMAGES from Day 8 of the action at the US Open at USTA Billie Jean King National Tennis Center at Flushing Meadows in New York on Monday.
Nadal had said that he did not know if he would be fit to play against Australian Kyrgios, after appearing close to retiring mid-match against Fritz on Centre Court.
Carlos Alcaraz enjoyed a dream return to action after more than three months out due to abdominal and hamstring injuries as the world number two claimed the Argentina Open title on Sunday.
The US Open turned over Arthur Ashe Stadium to the Williams sisters on Thursday for a prime-time first round doubles match that could have been Serena's last after the pair fell 7-6(5), 6-4 to the Czech duo of Lucie Hradecka and Linda Noskova.
IMAGES from Day 2 of the US Open played at Flushing Meadows in New York on Tuesday.
Gets standing ovation after first round loss at the US Open on Monday.
Osaka also reached the final of the Western & Southern Open, which was held at Flushing Meadows this year due to the COVID-19 pandemic, but had to withdraw against Azarenka due to an injury.
He will start his 2022 season in South America at the Cordoba Open in Argentina at the end of January.
World No. 1 Novak Djokovic has applied for special permission to enter the United States to participate in the ATP Masters 1000 events.
A 55-shot, marathon rally brought fans to their feet in Flushing Meadows on Friday but nearly leveled the two men who lived through it, Norwegian Casper Ruud and Russian Karen Khachanov, competing in their US Open semi-final.
Earlier, title holder Borna Coric beat American Sebastian Korda 7-6 (5), 6-4, while another home hope Taylor Fritz survived a first-set thriller to beat Czech Jiri Lehecka 7-6 (14), 6-2.
Bopanna was playing the US Open final for the second time in his career and this time as the oldest player at 43.
Kyrgios has been playing the best tennis of his career over the past couple of months
Novak Djokovic had hoped to have the crowd behind him as he began his bid to win the US Open and complete the calendar-year Grand Slam, but the Serb said the atmosphere was "not ideal" as Flushing Meadows fans roared on his underdog opponent.
The tournament initiative was to launch on Wednesday - Ukraine Independence Day - with the exhibition event at Louis Armstrong Stadium
'I know earlier in the tournament I said something in kind of a bad way and now I'm saying it in a good way: That it's because of your energy that I'm in the final'
IMAGES from the US Open matches played on Day 1 at the Flushing Meadows in New York on Monday.
A summary of Wednesday's action at the US Open.
IMAGES from US Open women's final played at the USTA Billie Jean King National Tennis Center at the Flushing Meadows in the Queens borough of New York City on Saturday.
Fourth-ranked Carlos Alcaraz and Norway's world number seven Casper Ruud also have a shot at top spot.
Images from Day 7 of the 2024 Australian Open in Melbourne on Saturday.
Alexis Olympia Ohanian donned braids with white beads on them, just as her mother Serena did when she first won the US Open as a teenager in 1999.
Images from Day 1 of the 2022 US Open at the USTA Billie Jean King National Tennis Center, in Flushing Meadows, New York, on Monday.
Second seed Dominic Thiem edged a first-set tiebreak before turning up the heat to romp into the US Open quarter-finals with a resounding 7-6(4), 6-1, 6-1 victory over Canadian youngster Felix Augur-Aliassime at Arthur Ashe Stadium on Monday.
India's Sumit Nagal advanced to the second round of the men's singles after outclassing American Bradley Klahn 6-1, 6-3, 3-6, 6-1 at the US Open in New York, on Tuesday.
Facing the prospect of empty stands at the first fanless Grand Slam since the coronavirus outbreak, top contenders at this year's US Open admit that the unprecedented new hush will take some getting used to.
The dominant Czech duo of Katerina Siniakova and Barbora Krejcikova rallied to beat Caty McNally and Taylor Townsend 3-6, 7-5, 6-1 in the US Open final on Sunday and collect their third Grand Slam doubles title of the year and sixth overall.
Images from Day 6 of the 2021 US Open in New York on Saturday.
Images from the US Open women's semi-finals on Thursday.
Eager to witness what many felt would be Serena Williams's final competitive match, thousands of fans poured into the Arthur Ashe stadium.
Emma Raducanu's US Open victory is among the "greatest achievements" in women's sport, men's world number eight Dominic Thiem said.
US Open champion Carlos Alcaraz crashed to defeat on his debut as world number one, losing to Canada's Felix Auger-Aliassime in their Davis Cup Finals group-stage clash on Friday.
'I have sort of a history with the towel. I used to have a towel when I was three, four years old and I would always carry it around. It was like my toy, basically. The towel resembles something special in my life.'
Halep withdraws from Western & Southern Open with injury.
Frances Tiafoe said his days of flying under the radar were over