The Czech has now won eight consecutive games at the Caja Magica and will face wildcard Sorana Cirstea or Caroline Garcia in the last 16.
A New York Times report last month said the showpiece event will not be held in the Turkish city and alternative venues were being considered.
Liverpool's Luis Diaz scored a hat-trick as they maintained their perfect Champions League campaign with a barnstorming second-half display in a 4-0 victory over Xabi Alonso's Bayer Leverkusen at Anfield on Tuesday.
Madrid's trip to San Sebastian was full of intrigue after Barca failed to beat Sevilla and the Catalan side's defender Gerard Pique said the title was now Madrid's for the taking.
A round-up of Saturday's action in Serie A, La Liga and Bundesliga.
Brazil had failed to impress at the Copa, drawing twice in the group stage while beating only Paraguay.
A stunning bicycle kick from Antonio Sanabria and a second-half header from Omar Alderete gave Paraguay a well earned 2-1 home win over Argentina.
Real Madrid beat Barcelona 2-1 in the first Clasico of the season in front of 86,422 fans at the Camp Nou on Sunday after a sensational strike from defender David Alaba and a late goal from Lucas Vazquez gave Carlo Ancelotti's side three points.
IMAGES from the UEFA Champions League matches played on Wednesday.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
Nadal was the favourite and top seed having lifted the Barcelona Open trophy last month but played below par on a sweltering spring day.
Juventus's hopes of reaching the Champions League last eight suffered a blow when the two-times European Cup winners slumped to a 1-0 defeat in their last-16 first leg at Olympique Lyonnais on Wednesday. Manchester City finally produced a Champions League performance worthy of their status as one of European football's elite clubs by beating Real Madrid 2-1 away in Wednesday's last-16 first leg after pulling off a stunning late fightback.
Robert Lewandowski and Raphinha both scored twice to help Barcelona thrash hosts Villarreal 5-1.
Images from Saturday's action in La Liga.
Former player and reserve team boss Santiago Solari has been put in caretaker charge after negotiations between the club and former Chelsea, Italy and Juventus boss Antonio Conte broke down on Monday, the club added.
Akshay walks his dog in London... Mouni is in Bali... Sonal in Dubai... And more!
Cristiano Ronaldo insists he is focused on being the perfect team member at Saudi side Al Nassr rather than collecting more individual accolades in the twilight of his career.
Real Madrid swatted aside Granada 4-1 on Thursday to ensure the La Liga title race will go down to the wire.
Real Madrid have increased their offer to sign Paris St Germain forward Kylian Mbappe to 170 million euros ($199.80 million) after having an initial 160 million euro bid rejected, Sky Sports reported on Thursday.
Real Madrid midfielder Casemiro and forward Eden Hazard have tested positive for COVID-19 ahead of their La Liga clash at Valencia, the Spanish champions said.
Madrid were not at their best but moved three points clear of rivals Barcelona.
Real Madrid paid tribute to Cristiano Ronaldo in a statement on their website on Tuesday after the Portuguese forward joined Juventus to end his nine-year stay with the Spanish giants.
France and Real Madrid forward Karim Benzema was found guilty of complicity in the attempted blackmail of a former international team mate over a sex tape on Wednesday and sentenced to a one-year suspended jail term.
Barcelona were hailed as La Liga champions-elect in the Catalan media after their 1-0 win at Real Madrid on Saturday, while the capital's press called for sweeping changes at Real after another domestic failure.
Barca will now visit seventh-placed Osasuna on Saturday before hosting Young Boys in the Champions League next week, when they will look to rebound following a 2-1 loss in their opening match at Monaco.
Real Madrid forward Vinicius Jr. score twice as his side punished a sloppy Liverpool to win 3-1, while Manchester City beat Borussia Dortmund 2-1 in Tuesday's Champions League quarter-final first leg.
Piotr Zielinski converted two penalties for Inter Milan as they played out a thrilling 4-4 draw with Juventus.
Loud cheering could be heard in almost every corner of the country after Spain won its fourth European Championship crown.
Delighted world number one Novak Djokovic said he was back to his best after winning a third Madrid Open title on Sunday, defeating Stefanos Tsitsipas 6-3, 6-4.
Spain and Real Madrid captain Sergio Ramos faced a new setback in a season littered with injury problems when his club said on Tuesday he had tested positive for COVID-19.
Real, chasing a 15th European Cup, levelled in the 83rd with Vinicius's penalty, after Rodrygo was felled by a clumsy challenge from Kim Min-jae, to set up a mouth-watering return leg in Madrid next week.
Paris St Germain will take their wage dispute with Kylian Mbappe to court after the French football league's governing body (LFP) ruled in favour of the France captain on Friday.
Playing without crowd will be peculiar: Suarez
All the action from La Liga and Serie A matches played on Monday
The two teams have met eight times in the European Cup, with Real winning four times and Liverpool three.
Federico Valverde has already made over 100 appearances at senior level - while winning silverware and recognition both with his current side Madrid and country Uruguay, and showing the physical, technical and mental attributes to become one of world football's outstanding midfielders.
'This is more than just a number -- it's a testament to our shared passion, drive, and love for the game and beyond,' Ronaldo said on X.
Real Madrid were dumped out of the Copa del Rey at the quarter-final stage on Thursday after losing 4-3 at home to Real Sociedad, while record 30-times winners Barcelona were sent crashing out of the Copa del Rey in a 1-0 defeat at Athletic Bilbao.
Rampant Eibar humiliated European champions Real Madrid with an emphatic 3-0 win in La Liga on Saturday.
Madrid won only two of their seven pre-season games
