Canadian Open champion Shelton was locked in an entertaining contest with Frenchman Adrian Mannarino in the day's opening match on Louis Armstrong Stadium when his tournament suddenly unravelled.
Novak Djokovic's battling victory under the lights of Arthur Ashe Stadium made him the oldest man to reach the last 16 at the US Open.
Top seed Roger Federer was finally forced to work hard for a win at the Swiss Indoors tournament as he fought back to beat Adrian Mannarino 4-6, 6-1, 6-3 in his quarter-final on Friday.
American lucky loser Reilly Opelka put up an intense battle to stun top seed Daniil Medvedev 7-6(5), 7-6(5) and reach the semi-finals in Den Bosch on Friday.
Eugenie Bouchard's best year was 2014 when she reached the semi-finals of the French and Australian Opens, and the final of Wimbledon.
Carlos Alcaraz, who advanced to the last eight in Cincinnati for the third time, has now won 36 of his last 38 matches.
Sabalenka relied on her trademark powerful serve to hold firm in the key moments, winning two tiebreaks to take her tally to 18 for the season, the most by any women's singles player in the professional era.
Roger Federer battered Adrian Mannarino so badly in a 6-2, 6-3, 6-2 romp on Thursday that the Wimbledon crowd began to root for the sorry Frenchman rather than their beloved six-times champion.
Second seed Novak Djokovic eased into the Wimbledon quarter-finals with a routine 6-2, 7-6(5), 6-4 win over France's Adrian Mannarino on Tuesday.
World No. 72 Nagal has a tough road ahead as he is placed in the same section of the draw as top seed and World No. 1 Jannik Sinner
Andy Murray says 'definite possibility' he's played his last Australian Open match
No 'triple bagel' but Djokovic thumps Mannarino to reach quarters
Lopez was cheered on by 22-time Grand Slam champion Nadal during his final event as a professional.
Another Indian, Yuki Bhambri and his Dutch partner Robin Haase also progressed to the quarter-finals.
Carlos Alcaraz reveals prize money attracted him to Saudi's Six Kings Slam
Carlos Alcaraz failed to reach the Paris Masters quarter-finals after a thrilling 6-1, 3-6, 7-5 defeat to local favourite Ugo Humbert
Top seed Carlos Alcaraz cruised into the quarter-finals of the Queen's Club Championships.
Carlos Alcaraz won two matches to lift Team Europe to a 13-11 victory over Team World for the Laver Cup title in Berlin.
Australian great Rod Laver says engravers should get to work putting the world number one's name on the Grand Slam trophy for an 11th time.
The 43-year-old Bopanna and 35-year-old Ebden, who claimed two doubles titles on the ATP Tour earlier this year, will next face the unseeded British pair of Jacob Fearnley and Johannus Monday on Sunday.
The Serbian second seed's match against France's Adrian Mannarino was delayed because of the epic five-setter between Gilles Muller and Rafael Nadal.
Roger Federer's late bid to secure his customary place in the season-ending ATP World Tour finals began with a routine opening round win over Adrian Mannarino in his home town tournament in Basel on Monday.
Novak Djokovic crashed to his first defeat of the season with a stunning 6-4, 6-4 loss to Alex de Minaur.
Somdev Devvarman suffered his second consecutive first round defeat, losing in straight sets to local player Adrian Mannarino in the euro 450,000 ATP Nice Open, in Nice, France. Ranked 66, the unseeded Indian lost 3-6, 6-7(7) to the French opponent, placed 13 places above him in the ATP ranking chart.
Three contenders for the men's singles title at the Australian Open, which starts on Sunday.
Hurkacz, Swiatek win as Poland march into United Cup final
Andy Murray was "back in the good books" with his wife on Thursday after his wedding ring and stinky shoes were returned to him.
Frenchman Adrian Mannarino also quit at two sets apiece against eight-times champion Roger Federer after sliding over on Centre Court and injuring his knee.
Spaniard Feliciano Lopez showed a compassionate streak in addition to a dangerous serve by apologising to the ball-boy he struck in the groin at the Australian Open.
Indian tennis ace Devvarman defeated Belgian Xavier Malisse 6-1, 3-6, 7-6 (5) in a two-hour third round contest at Indian Wells on Monday to set up a meeting with World No 1 Rafael Nadal next.
Carrying forward their good work at the Davis Cup, India's Somdev Devvarman and Rohan Bopanna have qualified for the BNP Paribas Open, an ATP Masters tournament in Indian Wells on Thursday.
India's Somdev Devvarman and South Africa's Kevin Anderson will clash in the final of the SA Tennis Open after scoring contrasting semi-final victories on Saturday. While fourth-seeded Anderson fought back after losing a first-set tie-breaker for a 6-7 (3-7), 6-0, 6-4 victory over Frenchman Adrian Mannarino, Devvarman dashed hopes of the final being an all-South Africa affair earlier with a 6-2, 6-4 win over wild card Izak Van der Merwe.
Shapovalov will meet Rafael Nadal for a place in the semi-finals.
Roger Federer and Rafael Nadal advanced to the quarter-finals of the BNP Paribas Open.
Somdev Devvarman stormed into the third round of the qualifying event of the French Open with a straight set thrashing of Daniel King-Turner of New Zealand in Paris on Wednesday.
Somdev Devvarman became the first Indian to qualify for the men's singles main draw at the French Open in 13 years as he crushed Frenchman Adrian Mannarino 6-4, 6-1 in Paris on Friday.
Mercifully the set flashed by in 16 breathtaking minutes as Federer whizzed into the quarter-finals with a 6-0, 7-5, 6-4 win.
Germany captain Michael Kohlmann was pleased to make 'positive history' after their first win over France in 84 years.
Top seed Carlos Alcaraz reached the semi-finals at the Queen's Club Championships with a straight sets victory over Bulgarian Grigor Dimitrov.
Second seed Novak Djokovic complained of a "hole" on Centre Court at Wimbledon after beating Adrian Mannarino in his delayed fourth-round match on Tuesday.