Arsenal secured a dominant 4-0 victory over Wigan Athletic in the FA Cup, while Leeds United edged Birmingham City on penalties, and Wolverhampton Wanderers battled to a 1-0 win against Grimsby Town.
Brentford scraped into the FA Cup fifth round with a narrow 1-0 win over sixth-tier Macclesfield, sealed by Sam Heathcote's second-half own goal after a spirited display from the hosts.
Manchester City defeated Salford City in the FA Cup, while Burnley suffered a surprising defeat to Mansfield Town. West Ham United and Norwich City also secured victories in their respective matches.
City, Liverpool all cruise in respective FA Cup matches played on Saturday.
Gabriel Martinelli scored his first hat-trick for Arsenal as the Premier League leaders beat second-tier strugglers Portsmouth 4-1 to reach the FA Cup fourth round.
Non-league Macclesfield produced perhaps the FA Cup's greatest upset on Saturday when they beat holders Crystal Palace 2-1 in a thirdround thriller, knocking Oliver Glasner's team out of the competition and sending the Moss Rose crowd into raptures.
Championship side Oxford United beat League Two's MK Dons on penalties after their match ended 1-1, while a couple of League One teams moved on, with Wigan Athletic beating Championship side Preston North End 1-0, and Port Vale defeating League Two's Fleetwood Town 1-0.
British media said Arsenal had allocated only 8,000 tickets for United supporters, citing safety concerns.
Arsenal manager Mikel Arteta called on his players to "live in the present" ahead of Sunday's visit to local rivals Tottenham Hotspur in a battle to stay ahead in the title race after their lead was cut short by successive Premier League draws.
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Former midfielder Fletcher made 342 appearances in all competitions with the club, the majority of them under Ferguson. He was also recently coach of the under-18 squad.
Two Bundesliga matches have been scrapped due to large amounts of snow and ice blanketing pitches across Germany, while a third-round FA Cup match on Saturday has also been postponed due to freezing conditions in Britain.
Antoine Semenyo has bewildered defences with 10 goals and three assists this season for Bournemouth.
Bodo/Glimt secured an upset 3-1 victory over Serie A leaders Inter Milan in the first leg of their Champions League playoff on Wednesday.
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The 44-year-old inherits a team in crisis, sitting seventh in the Premier League table -- a whopping 17 points behind leaders Arsenal -- and eliminated from both domestic cups.
Goals from Omar Marmoush and Antoine Semenyo powered Manchester City to a muchneeded 20 home win over Wolverhampton Wanderers on Saturday, lifting Pep Guardiola's men provisionally to within four points of leaders Arsenal in the Premier League title race.
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With 17 goal attempts compared to Chelsea's 10, Arsenal will feel they should have gone home with a bigger margin of victory and it will be all to play for in north London on February 3.
Manchester City's Antoine Semenyo made it two goals from two games for his new club and Rayan Cherki struck in stoppage time as Pep Guardiola's side beat holders Newcastle United 2-0 away in the first leg of their League Cup semi-final on Tuesday.
'Following successful live operation in the Emirates FA Cup, the Premier League will look to implement the system later this season.'
City then comfortably closed the game out and victory in their record-extending seventh consecutive FA Cup semi-final means they will face Crystal Palace, who beat Aston Villa 3-0 on Saturday, in the final on May 17.
Arsenal edged past Crystal Palace on penalties on Tuesday to reach the semi-finals of the League Cup.
Images from Saturday's FA Cup quarter-finals.
Images from the FA Cup semi-final between Crystal Palace and Aston Villa at Wembley stadium, London, on Saturday.
Crystal Palace's Eberechi Eze sparked a massive south London party by scoring the only goal to win the FA Cup 1-0 against Manchester City on Saturday and claim the club's first major trophy in their history.
Scholes also criticised Amorim's treatment of United academy graduate Kobbie Mainoo, who played for England in the Euro 2024 final and scored in United's FA Cup final win over Manchester City that year.
From Royal Challengers Bengaluru's historic first IPL title to star javelin thrower Neeraj Chopra finally breaking the iconic 90-meter mark to India women winning their first cricket World Cup, this was the year of long-awaited victories and record-breaking feats.
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Nottingham Forest reached the FA Cup quarter-finals as they beat fellow Premier League club Ipswich Town on penalties after the City Ground clash ended 1-1 after extra time on Monday.
Manchester City came back from a goal down to beat Bournemouth 2-1 on Sunday to book their spot in the semi-finals of the FA Cup.
Aston Villa striker Marcus Rashford scored twice in a 3-0 defeat of second-tier Preston North End in their FA Cup quarter-final at Deepdale on Sunday to earn a Wembley semi-final against fellow Premier League team Crystal Palace.
Crystal Palace have never won the FA Cup, Aston Villa last lifted the trophy in 1957 and Nottingham Forest have not managed it since 1959 but all three clubs go into this weekend's semi-finals genuinely believing this could be their year.
Promoted Sunderland, who have defied expectations to stay in the top half of the Premier League table, could be the worst affected with six players going to the tournament, while the likes of Fulham, Manchester United, Burnley and Crystal Palace will also have to make do without some key personnel.
A much-changed Liverpool were dumped out of the FA Cup by struggling second-tier side Plymouth Argyle, who pulled off a stunning 1-0 fourth round win.
A round-up of Saturday's fifth round action in the FA Cup
Some lament the FA Cup having lost much of its romance in recent years, in the face of obsession with the Premier League, but this tie had it in bucket loads.
Everton's Ashley Young came on as a second-half substitute but his 18-year-old son Tyler remained on the Peterborough bench.
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Manchester United clawed back from a goal down to beat Leicester City in a 2-1 fourth-round FA Cup victory on Friday at Old Trafford, thanks to a last-gasp controversial header from veteran defender Harry Maguire plus a strike from Joshua Zirkzee.