Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Liverpool started the ball rolling with a convincing 4-1 win at home to promoted Norwich and City responded a day later with an even more emphatic 5-0 victory at West Ham United.
Premier League leaders Chelsea moved 10 points clear at the top on Sunday despite being held by Burnley in an entertaining game played amid flurries of sleet and snow.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
Lucas ended a goal drought stretching back to 2010 and Divock Origi missed a late penalty as Liverpool beat fourth tier Plymouth Argyle 1-0 in an FA Cup third-round replay on Wednesday.
Arsenal's Premier League title charge gathered momentum as they moved two points clear at the top with a scrappy 1-0 victory over Newcastle United on Saturday as Leicester City's push faltered with a goalless home draw against Bournemouth.
Leicester City were give a Premier League reality check when the unlikely leaders lost 1-0 at Liverpool on Saturday after Manchester United slumped to a third consecutive league defeat to pile more pressure on manager Louis van Gaal.
News of all that's transpired on and off the football field
Eden Hazard has come under fire for some underwhelming performances and was benched by Jose Mourinho during Chelsea's woeful start to the campaign, but the Belgian says there is no problem with his manager and backed him to turn things around.
Everton won 1-0 at bottom club Sunderland to leapfrog Arsenal into fourth place in the Premier League on Saturday and the battle at the other end of the table intensified with wins for three clubs in danger of relegation.
Leicester City were left in touching distance of a fairytale first Premier League title on Sunday after Leonardo Ulloa's double helped them outclass Swansea City at a delirious King Power Stadium.
ManchesterCity moved up to third in the Premier League on Saturday while Newcastle United boosted their hopes of survival by coming back from two goals down at Liverpool to draw 2-2 and secure a precious point.
News of all that transpired on and off the football field.
Fulham forgot their Premier League struggles to sweep into the FA Cup fourth round with a 3-0 victory over fellow top-flight strugglers NorwichCity in a third-round replay on Tuesday.
Under-pressure Everton manager Roberto Martinez enjoyed some respite as his struggling side won for the first time in eight league matches.
A summary of Tuesday's League Cup matches.
McTominay injury takes gloss of vibrant United display
Images from the League Cup matches played on Tuesday
Manchester United and Chelsea secured places in the Champions League with wins on the final day of the Premier League season while Watford and Bournemouth were relegated along with bottom club Norwich City.
News of all that's transpired on and off the football field
It was not a day for FA Cup romantics as Manchester United scrambled past Sheffield United and minor league Eastleigh came within a whisker of causing the third round's only genuine shock.
Toronto FC's Justin Morrow, executive director of the Black Players for Change organization, said MLS players wanted to add their voices to the movement.
News of all that's transpired on and off the football field
Rediff.com recaptures these and other exciting sporting moments from the week gone by....
John Terry believes Chelsea's fortunes could be changing at a timely moment as the struggling English champions travel to Israel with the prospect of securing qualification for the knock-out stages of the Champions League.
United are 16th in the standings with a game in hand heading into the international break.
Aston Villa sacked manager Paul Lambert.
Cruzeiro have agreed to sell defensive midfielder Lucas Silva to Real Madrid, the Brazilian champions said on Thursday.
Chelsea's on-loan Brazilian international Alexandre Pato scored on his debut to help push pathetic Aston Villa to the verge of inevitable relegation with a seventh successive Premier League defeat on Saturday. Pato, the former Milan starlet who has been kicking his heels since joining from Corinthians two months ago, came on as a 25th-minute substitute and was immediately involved in the move which led to Ruben Loftus-Cheek netting his first league goal.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
News of all that transpired on and off the football field.
Alex Ferguson famously described the Premier League title run-in as 'squeaky-bum time' and leaders Leicester City and second-placed Tottenham Hotspur look best-placed to handle the pressure.
Pierre-Emerick Aubameyang scored twice to earn Arsenal a 3-2 Premier League win over Everton on Sunday, extending the Gunners' unbeaten start to 2020 and moving them back into the battle for European places. The win lifts Mikel Arteta's Arsenal side up to ninth place in the league with 37 points, while Everton remain without a victory at the Gunners in 24 years and a point adrift in 11th.
Late goals from Nicklas Bendtner and Theo Walcott spared Arsenal's blushes and kept them top of the Premier League in a 2-0 victory over Cardiff City as title rivals Manchester City and Chelsea also won on Wednesday.
Champions Chelsea begin title defence at home to Swansea City, while runners-up Manchester City kick-off at West Bromwich Albion
News of all that's transpired on and off the football field.
Manchester United's winless run continued but they gave under-fire coach Louis van Gaal crumbs of cheer with a committed display in an entertaining 0-0 draw with Chelsea while Arsenal went top of the table on Monday.
News of all that transpired on and off the football field.
Under-pressure Manchester United manager Louis van Gaal knows losing too many more matches 'could be the end of the world' but said he still has the full backing of the club's board.
Hull City edged towards Premier League safety while Wigan Athletic, will play in the third tier of English football.