Marcus Rashford and Alejandro Garnacho earned Manchester United a hard-fought 2-0 win
In his fifth World Cup, Ronaldo will arrive captaining a team of standout players who are widely seen as among the world's best but who have arguably underachieved on the biggest stage.
Here is a look at the clubs most likely to give City a run for their money next season.
Images from the English Premier League matches played on Saturday, April 13.
Manchester United bounced back from their defeat with a 4-1 win over Real Betis in the first leg of their Europa League last-16 tie.
Manchester United fought back to overpower West Ham United 3-1 and reach the FA Cup quarter-finals.
Portugal captain Cristiano Ronaldo has joined Saudi Arabian club Al Nassr on a 2-1/2 year contract.
IMAGES from the Premier League matches played on Saturday
Marcus Rashford continued his fine season as he scored again to help Manchester United beat Nottingham Forest 3-0 in their League Cup semi-final first leg on Wednesday.
Late Varane header earns stuttering Man Utd 1-0 win over Wolves
Cristiano Ronaldo is one of the greatest forwards of all time but his latest struggles with Manchester United and Portugal have raised many questions about whether his brilliant career is nearing a bitter end.
Following Manchester United's 7-0 drubbing at the hands of Liverpool at Anfield on Sunday, manager Ten Hag among former players came down heavily on their 'embarrassing' performance.
Amsterdam soccer club Ajax has had 11 players tested positive for COVID-19 a day before their Champions League tie against Danish side FC Midtjylland on Tuesday, RTL Nieuws reported on Monday.
Barcelona fought back to earn a 2-2 draw with Manchester United in a pulsating Europa League knockout round playoff first leg on Thursday.
Jarrod Bowen and Mohammed Kudus' second-half goals gave West Ham a 2-0 win over Manchester United in the Premier League's early game on Saturday, as the Hammers briefly moved into the top six.
Manchester United will be back in action in next season's Champions League after they hammered Chelsea 4-1.
Manchester United's hopes of moving second in the Premier League were scuppered as Michael Olise's stunning last-gasp equaliser earned Crystal Palace a 1-1 home draw on Wednesday.
Manchester United climb into sixth place with 3-0 West Ham win
Cristiano Ronaldo scored on his return to the starting line-up as Manchester United sealed a place in the Europa League knock-out rounds with a 3-0 victory over Sheriff Tiraspol at Old Trafford on Thursday.
Ronaldo's moments of brilliance, however, are getting ever rarer. Even in the Europa League, where he has started all four matches against mediocre opponents such as Sheriff Tiraspol and Omonia Nicosia, he has only scored once, off a penalty.
Rashford stepped off the bench to fire two late goals to put the seal on an eighth victory in a row in all competitions for the home side.
IMAGES from Saturday's action in the English Premier League.
Images from the Premier League matches played on Saturday, March 9.
IMAGES from the English Premier League matches played on Tuesday.
When Ralf Rangnick took over as interim manager of Manchester United he was hailed as the 'Godfather of German coaching'
Wolverhampton Wanderers stunned Tottenham Hotspur 2-1 with stoppage-time goals from Pablo Sarabia and Mario Lemina on Saturday, thwarting the visitors in their bid to reclaim top spot in the Premier League table.
Images from UEFA Champions League matches played on Wednesday.
Bayern expect a top performance against Manchester United, says Tuchel
Manchester United crushed Newcastle United's hopes of a claiming a first domestic trophy for nearly 70 years with a clinical 2-0 victory in the League Cup final at Wembley on Sunday.
Manchester United climbed to third place in their quest for a berth in next season's Champions League.
Monday's resumption was also a chance for those jostling at the top of the table to lay down a marker and for the strugglers to enjoy a fresh start.
Defender Raphael Varane scored his first Premier League goal as Manchester United returned to winning ways with a comfortable 3-0 victory over Brentford on a night of potential farewells at Old Trafford. Bruno Fernandes and Cristiano Ronaldo, the latter with a penalty, also netted on Monday, which is the last home fixture of a difficult campaign for United.
With Crystal Palace dangerously close to being relegated, manager Patrick Vieira was sacked after 20 months in charge.
A ninth successive win in all competitions for United was celebrated with real vigour, as they moved to within a point of City in second, giving Arsenal the chance to go eight points clear at the top of the standings with a win over Tottenham Hotspur on Sunday.
IMAGES from the Premier League matches played on Saturday.
Manchester United conceded two late own goals to allow Sevilla to snatch a 2-2 draw in the first leg of their Europa League quarter-final at Old Trafford on Thursday.
Ronaldo's 62nd minute strike was his 17th league goal this season
Ronaldo back for Man Utd but injured Shaw faces weeks out
Chelsea have completed the transfer of defender Wesley Fofana from Leicester City, both Premier League sides said on Wednesday, with the Frenchman signing a seven-year contract with the west London club.
Manchester United produced an utterly unexpected 2-1 victory over old rivals Liverpool in the Premier League at Old Trafford on Monday to turn fan protests against the club's owners into a rare night of celebration.