Champions Manchester City could only muster a 2-2 Premier League draw with Brighton & Hove Albion on Saturday.
Arsenal, who had 23 shots to Newcastle's seven, piled on the pressure late on to try to reduce the deficit but Newcastle manned the barricades to take a healthy lead to St James' Park.
City slumped to a fourth consecutive loss in all competitions with a 2-1 defeat at Brighton & Hove Albion in the Premier League on Saturday
Former Bayern Munich and Liverpool winger Xherdan Shaqiri announced his retirement from international football on Monday
Images from the UEFA Champions League group matches played on Wednesday night.
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Liverpool held their nerve to win an astonishing penalty shoot-out 11-10 and edge out Chelsea in the English League Cup final on Sunday after a rip-roaring contest had somehow ended 0-0 after extra time at Wembley.
Victor Boniface rattled the post with a powerful shot eight minutes after the restart as Leverkusen picked up where they had left off.
IMAGES from the English Premier League matches played on Wednesday.
A summary of Saturday's action in the English Premier League.
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
In a thriller at Anfield, a weakened Liverpool side came back from the brink to beat Leicester City on penalties after a 3-3 draw, setting up a semi-final against Arsenal.
Tracking the key moves this week in the European transfer market
Mohamed Salah's early penalty in the return match on Thursday gave Liverpool a 1-0 victory in Italy but Klopp's side went out 3-1 on aggregate.
Alexander Isak's early headed goal lifted Newcastle to a 1-0 victory over Arsenal on Saturday at St. James' Park, as Eddie Howe's men delivered a blow to Arsenal's title chase with their first win in six Premier League outings.
Liverpool and Manchester City having the potential to "dominate" European football, former Scotland international Graeme Souness has said.
Liverpool's 2-0 victory at Cardiff City on Sunday restored their two-point lead over champions Manchester City, who have played a game less.
Postecoglou moves a step closer to making good on his reputation for securing silverware in his second season at clubs and delivering a first cup for Spurs since they won the League Cup in 2008.
Liverpool could be crowned champions of England for the first time in 30 years, on Wednesday, having turned the Premier League title race into a procession.
The Gunners' only league defeat of the campaign was in September away to one of England's traditional top-six clubs, Manchester United, drawing criticism that their strong start to the season was based on wins against lesser opposition.
IMAGES from the English Premier League matches played on Saturday.
Juergen Klopp's side will meet the winners of Sunday's other semi-final between Chelsea and Crystal Palace in the May 14th final
Chelsea have been charged with two counts of disorderly conduct during their ill-tempered 1-1 draw against Liverpool at the weekend, the Football Association said on Wednesday.
A round-up of Wednesday's action in the UEFA Champions League.
Liverpool's Slot not nervous ahead of Anfield debut
Images from the English Premier League matches played on Saturday.
Holders Liverpool survived a penalty shootout to see off third-tier Derby County
Young becomes oldest Everton scorer in rout of Wolves
Another Liverpool great, Graeme Souness, said Klopp had produced a "fabulous" side.
IMAGES from the English Premier League matches played on Tuesday.
Premier League rejected Chelsea request to postpone Wolves game, says Tuchel.
A round-up of Wednesday's action in the UEFA Champions League.
The win moved Juergen Klopp's side above Chelsea in the table and 11 points behind leaders Manchester City with a game in hand.
Fabinho's first-half goal earned Liverpool a 1-0 win at Burnley
A round-up of Saturday's action in the Premier League.
Luton pulled one back on the half-hour mark when Chelsea keeper Kepa Arrizabalaga failed to keep out Jordan Clark's low effort which squeezed between his hand and leg into the net.
Spurs Premier League match at Brighton postponed due to COVID-19
With Manchester City mired in a six-game winless slump and facing one of their biggest challenges this season at Liverpool this weekend, manager Pep Guardiola said the onus was on him to prove he can right the ship.
Hazard extra-time goal sends 10-man Real Madrid through to Copa del Rey final.
Mohamed Salah's 100th Premier League goal helped Liverpool cruise to a 3-0 victory at 10-man Leeds United on Sunday in a match that was marred by a nasty injury to teenager Harvey Elliott.