Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
"Diego Costa's out which means we have to solve that problem in 24 hours," new interim coach Guus Hiddink told reporters.
Manchester United manager Jose Mourinho unleashed an impassioned defence of his work on Friday as he responded to critics of his team's failure to make the last eight of the Champions League.
Chelsea manager Antonio Conte got the upper hand on Jose Mourinho for the second time this season as his double-chasing side beat 10-man Manchester United 1-0 at Stamford Bridge to reach the FA Cup semi-finals on Monday.
Arsenal travel across town to a vengeful Chelsea on Saturday knowing that another depressing defeat at Stamford Bridge would see their Premier League title hopes swept away with the lunchtime leftovers.
A last-minute own goal gave Liverpool a 2-1 win over Tottenham Hotspur to keep them top of the Premier League but Manchester City stayed two points behind having won at Fulham. Huddersfield Town were relegated after their defeat by Crystal Palace.
Lucas Moura scored twice as Tottenham Hotspur romped to a 3-0 English Premier League win over Manchester United at Old Trafford on Monday as Jose Mourinho's team's defensive frailties were brutally exposed once again.
Manchester City's eight point advantage after 11 games is leading to talk of the Premier League title race being over in November, but as Manchester United manager Jose Mourinho noted - English football has a habit of throwing up surprises.
Chelsea plucked a performance straight from the Jose Mourinho textbook -- with John Terry writing a chapter all of his own -- as they grafted to a 0-0 draw at Arsenal on Sunday that leaves them almost certain to claim the title.
With no European prizes left to chase this season, England's top clubs are focussed on winning the Premier League title, although that goal looks beyond all but Chelsea.
A stunning strike from Jordan Henderson helped Liverpool secure a comfortable 2-1 win at Chelsea on Friday that ended the London club's unbeaten start to the season and underlined the growing potential of Juergen Klopp's side.
Antonio Valencia's early thunderbolt put Manchester United en route to a 4-0 Premier League victory over Everton on Sunday, but they needed a flurry of late goals to finally subdue their unfortunate visitors.
Following is a match by match look at the English Premier League's season-opening weekend fixtures:
This and more from the happenings in the world of football
Chelsea opened up a six-point lead at the top of the Premier League despite being held to a 1-1 draw against top-four hopefuls Southampton in an absorbing game at Stamford Bridge on Sunday.
The challenge against champions Chlesea on Sunday is for Manchester United to show that they can replicate the confident and businesslike win that City showed a month ago.
News of all that transpired on and off the football field.
Images from the English Premier League match played between Chelsea and Stoke City on Monday
If, as former British Prime Minister Harold Wilson once said, a week is a long time in politics, four and a half months in football clearly represents an eternity.
Five talking-points from the Premier League weekend after Manchester City suffered a shock home loss to Crystal Palace, meaning that Liverpool stayed four points clear at the top following their win over Wolverhampton Wanderers.
Chelsea midfielder Cesc Fabregas gave his manager a reminder of his talents by scoring twice in extra time as they fought back from two goals down to knock Premier League champions LeicesterCity out of the League Cup 4-2 on Tuesday.
This and more from the happenings in the world of football
Chelsea manager Jose Mourinho stoked up his war of words with Manuel Pellegrini on Monday by questioning the Manchester City manager's sums.
Following Chelsea's tame draw against Manchester City, questions are being raised about the Jose Mourinho-managed team's game plan and attitude.
It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
Images from the English Premier League matches played across England on Tuesday
'You cannot sack all the players so sack the manager -- whether right or wrong'
News of all that transpired on and off the football field.
But the under fire Blues manager gets former player Frank Lampard's backing
Liverpool took over at the top of the Premier League table despite being held to a 0-0 draw against Manchester United in a scrappy match on Sunday.
With as much bravado as he could muster, a grim-faced Jose Mourinho said he would not walk out of Chelsea despite his champions suffering their fourth defeat in eight Premier League matches and languishing 16th in the table.
Images from the English Premier League matches played on Sunday
Images from Tuesday's action in the UEFA Champions League.
Antonio Conte's title ranks as one of the finest of the Abramovich era because this title was so unexpected. Out of the blue, in fact.
Chelsea look capable of beginning a period of sustained domestic dominance. The average age of their squad is 26.9 -- with most of their key players in or approaching their prime years.
Images from the English Premier League matches played on Tuesday
Mario Balotelli enjoyed a rare moment of ecstasy in a Liverpool shirt by inspiring a 2-1 win over Swansea City in the League Cup on Tuesday while Chelsea had to call for reinforcements to see off Shrewsbury Town.
News of all that's transpired on and off the football field
Bitter rivals Arsene Wenger and Jose Mourinho had wildly contrasting afternoons on Saturday as Arsenal went top of the Premier League and champions Chelsea lost again with their manager being sent off.