She beat Jasmine Paolini in the quarter-finals and then made it back-to-back wins over top 10 players as she also defeated compatriot Coco Gauff by 6-1, 6-2 in the semifinals.
Sinner will face 19-year-old Learner Tien for the title.
Defending champion Coco Gauff bowed out of the China Open after suffering a 6-1, 6-2 semifinal loss to compatriot Amanda Anisimova, in Beijing, on Saturday.
Sinner has a perfect 10-0 record against de Minaur, and he is currently number two in the ATP Live Race to Turin, having qualified for the season-ending ATP Finals. Sinner has reached the last four in seven out of his previous eight tournaments this year.
Defending champion Coco Gauff cruised into the semifinals of the China Open with a dominant 6-3, 6-4 win over Germany's Eva Lys, in Beijing, on Thursday.
India's top doubles pair Satwiksairaj Rankireddy and Chirag Shetty bowed out of the China Open Super 1000 badminton tournament after suffering a straight-game defeat to Malaysian second seeds Aaron Chia and Soh Wooi Yik in the semifinals in Changzhou on Saturday.
This is the first time that Sindhu has lost to a fellow Indian in an international event in seven years.
Prannoy saves five match points to progress, Lakshya Sen exits China Open
A new report indicates a decrease in international student enrolments in US colleges, but India remains the top source of international students.
'I had a deja vu moment on court. I had match point on the same side of the court, went for the same serve and was telling myself the same things. I had goosebumps, it was really special. It's great to win here again.'
Defending champion Jannik Sinner defeated Daniel Altmaier to avenge a loss two years ago at the French Open as he marched into the third round of the Shanghai Masters with a 6-3, 6-3 victory over the German.
Medvedev in Shanghai semis as Rinderknech joins cousin Vacherot in last four
In women's singles, Sindhu, a two-time Olympic medallist and 2019 world champion, will have to recover from the shock defeat against fellow Indian Unnati Hooda at the China Open.
World Junior Ch'ships: India off to flying start; Sri Lanka edge UAE in thriller
Rohan Bopanna and his Croatian partner Ivan Dodig suffered a shock loss to the pair of Francisco Cerundolo and Nicolas Jarry in the first round match of the China Open.
This was their third semifinal appearance on the BWF Tour this season, having earlier reached the last four at the Singapore Open and India Open.
'When I played against Sindhu didi in China, I am happy I managed to play better than I did last time.'
India squandered a golden opportunity to return with two titles as both Lakshya Sen and the men's doubles pair of Satwiksairaj Rankireddy and Chirag Shetty signed off with runner-up finishes at the Hong Kong Open Super 500 in Hing Kong on Sunday.
Satwiksairaj Rankireddy and Chirag Shetty outclassed Ong Yew Sin and Teo Ee Yi of Malaysia in straight games to enter the semi-finals of the China Open Super 100.
Lakshya Sen entered his first major final in two years after edging out Chinese Taipei's Chou Tien Chen in straight games, while the men's doubles pair of Satwiksairaj Rankireddy and Chirag Shetty also stormed into the summit clash.
The Nagpur shuttler was no match for Yamaguchi in the opening game as the Japanese took a massive eight-point lead at 12-4 before closing out the game at 21-10.
Tanvi, Unnati and Bhargav Ram-Viswa Tej to lead strong Indian line-up in BWF World Junior Championships
'We didn't get really any rhythm. We didn't start off that well. We gave away easy points (in the third game). We should have been a bit smarter. But, credit to them.'
Indian shuttlers who competed at the Paris Olympics, including PV Sindhu, Lakshya Sen and the men's doubles pair of Satwiksairaj Rankireddy and Chirag Shetty, are giving the tournament, the year's final BWF Super 1000 event, a miss.
Satwiksairaj Rankireddy and Chirag Shetty assured India of a medal at the World Championships after defeating Malaysia's two-time Olympic medallists Aaron Chia and Soh Wooi Yik, in the quarter-finals in Paris.
Heading into the final, Gauff had lost the first set in three straight matches and the former U.S. Open champion seemed determined to buck that trend, serving to love in the opening game and breaking early for a 2-0 lead.
Karolina Muchova snapped U.S. Open champion Aryna Sabalenka's 15-match win streak to shock her 7-6(5) 2-6 6-4 in the China Open quarter-finals on Friday, while Olympic champion Zheng Qinwen beat Mirra Andreeva 5-7 6-0 6-4 to reach the semi-finals.
The 27-year-old began working with Mouratoglou ahead of the China Open in September last year, as she sought to reignite her career following a patchy run of form after returning to the tour from a long maternity break.
Malvika Bansod pulled off a sensational straight-game victory over Paris Olympics bronze medallist Gregoria Mariska Tanjong of Indonesia in the women's singles opening round.
Sindhu regained control in the decider, maintaining a steady lead to close out the contest and secure a hard-fought win in 62 minutes.
Indian shuttlers Lakshya Sen, Ayush Shetty, and Tharun Mannepalli progressed to the second round of the men's singles competition at the Macau Open Super 300 badminton tournament after registering fine wins on Wednesday.
Coco Gauff fought back from a set down to beat Spain's Paula Badosa 4-6, 6-4, 6-2 in the semi-finals of the China Open in Beijing on Saturday.
French Open and Wimbledon champion Alcaraz, who won both of his previous meetings with Sinner this year, recovered from a slow start to wrap up victory in three hours, 21 minutes and improve his head-to-head record with the Italian to 6-4.
Carlos Alcaraz defeated Tallon Griekspoor of the Netherlands 6-1, 6-2 at the China Open on Sunday to capture his 200th career tour victory.
It's a good sign, best is yet to come: Satwik-Chirag on semifinal finish at Singapore Open
World number one Jannik Sinner produced a sublime semi-final display as he fought back from a set down to beat American Tommy Paul 1-6, 6-0, 6-3 on Friday to set up an Italian Open final showdown with Carlos Alcaraz.
Indian challenge ends after Satwik-Chirag bow out in opening round of China Open
'This strike has certainly enhanced your image.' 'Otherwise, people would have called you a damp squib, capable of doing nothing except talking big.'
Grandmaster R Praggnanandhaa played out a second straight draw against Turkey's Gurel Ediz while Aravindh Chithambaram crashed through the defences of Germany's Vincent Keymer in the second round of the Prague Masters on Friday.
The rising tennis stars, who have captivated the world with their exceptional talent, embarked on a memorable journey to the Forbidden City, one of the city's most iconic landmarks.