Fourth seed Kei Nishikori's hopes of making another magical U.S. Open run came to a quick end on Monday as last year's runner-up fell at the first hurdle, falling 6-4, 3-6, 4-6, 7-6 (6), 6-4 to Frenchman Benoit Paire.
World number one Novak Djokovic lost to rivals Roger Federer and Andy Murray in the finals of US Open warm-up events but the Serb insists those defeats have aided his preparations for the last grand slam of the season.
Roger Federer blamed troubled preparations for his US Open quarter-final exit on Wednesday, saying he had spent most of the time leading up to the year's final Grand Slam worrying about his back instead of focusing on training.
Marathon man Kei Nishikori secured a monumental upset by sweating out a 6-4, 1-6, 7-6(4), 6-3 win over world number one Novak Djokovic at the U.S. Open on Saturday to become the first Japanese man to reach a Grand Slam final.
Five-times champion Roger Federer reached his first US Open final in six years as he raced past fellow Swiss Stan Wawrinka 6-4, 6-3, 6-1 at Flushing Meadows in the semi-finals on Friday.
Daniil Medvedev continued his march towards a first Grand Slam title on Wednesday, powering into the US Open semi-finals with a clinical 7-6(6), 6-3, 7-6(5) victory over childhood friend Andrey Rublev.
World number one Novak Djokovic was sensationally disqualified in the US Open fourth round on Sunday after striking a line judge with a ball following a point during the first set of his match against Spain's Pablo Carreno Busta.
Issues of sexism, officiating double standards and adverse playing conditions have dominated the 50th anniversary of the U.S. Open, raising uncomfortable questions and prompting authorities to promise a review of existing policies.
Millman advanced to a quarter-final match-up against sixth seed Novak Djokovic.
Overpowers Svitolina to reach second straight US Open final
Karolina Pliskova suffered a narrow US Open defeat at the hands of Angelique Kerber on Saturday, but the Czech 10th seed also proved her mettle as one of the most dangerous attacking players in women's tennis.
Serena Williams will be wary of another semi-final slip-up when she takes to the Arthur Ashe Stadium court on Thursday to face 10th seed Karolina Pliskova for a spot in the US Open final.
Serena Williams stormed into the US Open quarter-finals in record-smashing style on Monday by easing past Kazakhstan's Yaroslava Shvedova 6-2, 6-3 to claim her record 308th Grand Slam match win.
Venus Williams's renaissance year continued on Tuesday when she downed Petra Kvitova 6-3, 3-6, 7-6(2) in an electrifying atmosphere to set up an all-American US Open semi-final against Sloane Stephens.
Sumit Nagal lived a dream when he took on one of the greatest players of all time at a packed Arthur Ashe stadium in a US Open first-rounder.
Wimbledon champion Garbine Muguruza notched up her first ever victory on Arthur Ashe Stadium with a 6-0, 6-3 win over American Varvara Lepchenko at the US Open on Monday.
IMAGES from Day 7 of the US Open on Sunday
Images from Day 1 of the US Open in New York, on Monday.
With a 6-2, 6-1 3rd round win over Swedish Johanna Larsson at the US Open at Flushing Meadows on Saturday, Serena recorded her 307th Grand Slam victory and in doing so went past legendary Martina Novratilova to record the most wins in a major by a woman.
Rafael Nadal, who said his injured wrist is improving daily, beat Denis Istomin of Uzbekistan 6-1, 6-4, 6-2 in his first-round match on Monday's opening day of the year's last Grand Slam.
Sumit Nagal brought himself recognition after taking a set off Roger Federer in the opening round match of the US Open, which he eventually lost 4-6, 6-1, 6-2, 6-4. However, Haryana lad said he has yet not been approached by any new sponsors.
IMAGES from Day 8 of the US Open on Monday
Andy Murray made another of his trademark stirring fightbacks as the third-seeded Scot powered past Frenchman Adrian Mannarino after dropping the first two sets of their second round encounter at a sweltering US Open in New York, on Thursday.
World No 1 Novak Djokovic beat Roger Federer 6-4, 5-7, 6-4, 6-4 to win the US Open title at the Flushing Meadows in New York on Sunday.
Unseeded Sloane Stephens crushed fellow-American Madison Keys 6-3, 6-0 to win her maiden Grand Slam, in the US Open final, in New York on Friday.
Keys and Stephens to put friendship to grand slam test
Germany's second seeded Angelique Kerber beat Czech Karolina Pliskova 6-3, 4-6, 6-4 to win the US Open final on Saturday, and collect her second Grand Slam title of the year.
While 40 have tried only nine times have both Williams sisters been beaten by the same player at the same tournament and that list reads like a Grand Slam Hall of Fame with names that include; Steffi Graf, Martina Hingis, Lindsay Davenport, Justine Henin and Kim Clijsters, who like Pliskova, pulled the double off at the US Open.
It was his first victory ever against a player ranked in the top two and it avenged the semi-final loss at the Rio Olympics where Murray went on to win gold and Nishikori settled for bronze.
Garbine Muguruza was once again left to sift through the remains of another failed US Open campaign after the third-seeded Spaniard suffered a shock 7-5 6-4 second round upset by unheralded Latvian Anastasija Sevastova on Wednesday.
Former world No.1 Ana Ivanovic suffered a shock 6-7(4), 1-6 loss against Denisa Allertova of Czech Republic in the women's singles first round at the 2016 US Open on Tuesday. Ivanovic, the 2008 French Open winner, started off well but failed to maintain her momentum. With the scored tied 6-6, the first set went into tie-break and the Serbian star failed to keep her nerves.
Images from the US Open final played at Flushing Meadows on Sunday
Four times now, twice at Wimbledon (2018, 2019) and at the US Open (2018, 2019) Serena Williams has come agonizingly close to that 24th Grand Slam only to fall at the final hurdle.
Bianca Andreescu, 19, the first Canadian to win a major in the professional era, prevented Serena Williams from equalling Margaret Court's record of 24 Grand Slam singles titles.
Images from Day 2 of the 2020 US Open in New York
Images from the third day at the US Open, the final Grand Slam tournament of the year, in New York, on Wednesday:
Flavia Pennetta crushed Romanian second seed Simona Halep 6-1, 6-3 to kick off a packed day of action at the U.S. Open on Friday with a stunning upset that put the Italian into her first Grand Slam final.
Lleyton Hewitt waved goodbye to the US Open on Thursday, the tenacious Australian dragged kicking and screaming to the Flushing Meadows exit by countryman Bernard Tomic.
IMAGES from Day 3 of the US Open in New York on Wednesday.
In the last eight weeks Novak Djokovic has resembled the Grand Slam machine that held all four major titles at the same time in 2016, wining three of his last four events including Wimbledon and US Open.