India's mixed doubles pair of Dhruv Kapila and Tanisha Crasto fell short in the semi-finals of the German Open Super 300.
Rakshitha Sree Santosh Ramraj lost to Mia Blichfeldt of Denmark 12-21, 12-21 to bow out of women's singles quarterfinals.
Later in the day, Commonwealth Games champion Lakshya Sen will face Chico Aura Dwi Wardoyo of Indonesia.
Two-time Olympic medallist P V Sindhu shocked World No. 2 Wang Zhi Yi of China to storm into the quarterfinals of the World Championships, in Paris on Thursday.
Gayatri Gopichand and Treesa Jolly lost in straight games against China's Li Yi Jing and Luo Xu Min.
A gold medallist at the 37th National Games, Mannepalli was trailing 4-7 in the first game before rallying to 12-9. He then took control and scored six straight points from 15-11 to seal the game.
Kidambi Srikanth enters second round of Canada Open
This is the first time that Sindhu has lost to a fellow Indian in an international event in seven years.
Lakshya Sen suffered a stunning first round exit as India's challenge came to an end in the German Open.
Kvitova and Vekic had played twice on Saturday after a rain delay on Friday but it was the Czech who did not drop a set in the entire tournament.
In the upcoming German Open, Lakshya Sen will spearhead India's challenge at the Super 300 tournament.
Sankar Muthusamy Subramanian caused a major upset by knocking out World No 2 Anders Antonsen of Denmark in a thrilling three-game contest to reach the men's singles quarter-finals.
Lakshya Sen's giant-killing run ended with a straight-games defeat to Thailand's rising star Kunlavut Vitidsarn in the final of the German Open Super 300 badminton tournament, Muelheim An Der Ruhr, on Sunday.
Ishaan and Sai Pratheek took just 30 minutes to get the better of English duo
Sen will now face the winner of the other quarter-final match between Olympic champion and top seed Viktor Axelsen and India's Kidambi Srikanth on Saturday.
Sindhu, a 2019 World Champion, lost 14-21, 21-15, 14-21 to Zhang in a match that lasted 55 minutes.
Lakshya Sen continued his rich vein of form as he sent the world No. 1 and top-seed Axelsen packing
The World No 11 Srikanth will take on China's Lu Guang Zu in the next round.
Russian Nikolay Davydenko clinched his first title of the season on Sunday when he crushed Frenchman Paul-Henri Mathieu 6-4, 6-2 to win the German Open.
Dinara Safina of Russia came from a set down to win the German Open on Sunday with a 3-6, 6-2, 6-2 victory over seventh-seeded compatriot Elena Dementieva.
World number one Justine Henin was dumped out of the German Open on Thursday, losing 5-7, 6-3, 6-1 to 13th seed Dinara Safina of Russia in the third round.
Ana Ivanovic fought back from a set to beat Svetlana Kuznetsova 3-6, 6-4, 7-6 in the final of the German Open.
The defending champion lost to Russia's Nadia Petrova 2-6, 3-6 in the quarterfinal.
The Russian battled back from a set down to beat French Open champion Justine Henin-Hardenne in the final.
India's Kidambi Srikanth was ousted in men's singles but the women's pair of Treesa Jolly and Gayatri Gopichand progressed to the semifinals of the Macau Open Super 300 badminton tournament in Macau on Friday.
The Indian will have yet another uphill task at hand when he takes on Axelsen, the baby-faced badminton giant, who has terrorised his opponents in the last few years.
The Indian ace beat ninth seeded Sung Hwan Park of Korea to enter the semi-finals of the German Open.
The Belgian advanced to the German Open semi-finals with a 6-4, 7-6 victory over Russian Svetlana Kuznetsova.
Indian shuttler Arvind Bhat ended a seven-year title drought by winning the German Open Grand Prix Gold with a gruelling three-game upset victory over 12th seed Dane Hans-Kristian Vittinghus in the men's singles final in Mulheim an der Ruhr.
The world number one has been ordered to rest by doctors.
Justine Henin-Hardenne survived three match points to overcome Kim Clijsters 6-4, 4-6, 7-5 in a thrilling all-Belgian German Open final
Indian shuttler Anand Pawar notched up a straight-game win over sixth seed Viktor Axelsen to join compatriot Ajay Jayaram in the pre-quarterfinals of the German Open badminton championship in M lheim an der Ruhr, Germany.
World number three Maria Sharapova and 10th-ranked Daniela Hantuchova have pulled out of next week's German Open in Berlin, organisers said on Wednesday.
Martina Hingis was knocked out of the German Open, losing 6-4, 6-0 to fellow Swiss Patty Schnyder.
But Pullela Gopichand, Anup Sridhar, Arvind Bhat and Abhinn Shyam Gupta were shown.
They went down to Japan's Shoji Sato and Huawien Xu of France respectively at the German Open badminton tournament.
Chetan Anand, Nikhil Kanetkar and Aparna Popat bowled out in the second round.
Senior Indian shuttler Arvind Bhat advanced to the semi-finals of the $120,000 German Open Grand Prix Gold after registering a straight-game victory over Danish 14th seed Viktor Axelsen in Mulheim an der Ruhr.
Former National champion Bhat entered the second round after Scott Evans retired midway at 21-9, while Pawar defeated Eetu Heino of Finland 21-12, 21-16.
The Belgian injured her right leg in an awkward slide to the net during a third-round match against Switzerland's Patty Schnyder.
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