Sergio Aguero scored five times in 20 minutes including an eight-minute hat-trick as Manchester City came from behind to thrash Newcastle United 6-1 and go back to the top of the Premier League table on Saturday.
Liverpool snatched three points with a wild 1-0 victory over relegation-threatened Nottingham Forest.
Images from the English Premier League matches played on Saturday
Wolverhampton Wanderers stunned Tottenham Hotspur 2-1 with stoppage-time goals from Pablo Sarabia and Mario Lemina on Saturday, thwarting the visitors in their bid to reclaim top spot in the Premier League table.
Luis Suarez warmed up for next week's FA Cup final with a hat-trick in Liverpool's 3-0 win at Norwich City in the Premier League on Saturday while high-flying Newcastle United were thumped 4-0 at lowly Wigan Athletic.
Liverpool drew 1-1 at third division Luton Town and Newcastle United were goalless at Stoke City in the FA Cup fourth round.
England forward Alan Smith joined Newcastle United from Premier League champions Manchester United on Friday in a five-year deal.
Bernardo Silva and Jack Grealish scored three minutes apart as Manchester City came from behind to beat Premier League newcomers Luton Town.
Kieron Dyer and Lee Bowyer were sent off for fighting each other as Newcastle United ended with eight men on the pitch in a 3-0 defeat by Aston Villa.
Six weeks ago, with Newcastle United in the Premier League's relegation zone and still looking for a first win of the season, Alan Pardew seemed highly unlikely to reach his fourth anniversary as manager in December.
Manchester City maintained their pressure on Arsenal with a 2-0 win over Newcastle United in their Premier League match on Saturday.
Van Dijk was sent off for fouling Alexander Isak during the first half and appeared to remonstrate with referee John Brooks before walking off the pitch.
Chelsea's Premier League title defence continued to splutter on Sunday when they could only draw 1-1 at Newcastle United and missed their chance of returning to the top of the standings.
Newcastle United produced an astonishing fightback to draw 4-4 at home to Arsenal on Saturday after trailing 4-0 with just 26 minutes gone in the Premier League on Saturday.
Alan Pardew was hailed last season as a steady hand on the Newcastle United tiller but finds himself contemplating an impending relegation battle ahead of a clash with wounded champions Manchester City on Saturday.
Britain's Mo Farah capped his illustrious competitive racing career with a fourth-place finish at the Great North Run half-marathon in Newcastle on Sunday.
An injury-hit Newcastle United stunned Tottenham Hotspur with a 3-2 victory in the EPL.
Defending champions Manchester City scintillated a stellar performance to record an emphatic 5-0 win over Newcastle, and reduced Chelsea's advantage to five points in the Premier League table on Saturday at Etihad Stadium.
Manchester United crushed Newcastle United's hopes of a claiming a first domestic trophy for nearly 70 years with a clinical 2-0 victory in the League Cup final at Wembley on Sunday.
Manchester City went top of the Premier League after securing a controversial 2-0 win at Newcastle United on Sunday with an early Edin Dzeko goal and a stoppage time effort from Alvaro Negredo.
Israel debutant Yarden Shua scored an 86th-minute winner as they upset more fancied Belgium 1-0 in Budapest on Sunday.
Kevin de Bruyne struck twice to inspire Manchester City to a dominant 4-2 win at Crystal Palace on Saturday and move the champions level on points with Liverpool at the top of the Premier League table.
Third-placed Aston Villa are the surprise package of the season and Unai Emery's side face relegation-threatened Burnley while fifth-placed Spurs host a resurgent Bournemouth who have 19 points from their last seven games.
Manchester City and Arsenal closed in on Premier League leaders Liverpool with contrasting victories on Saturday as Manchester United's bubble was burst by Fulham.
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Tottenham Hotspur maintained their late-season drive for European soccer and pushed Newcastle United further towards relegation when they won a one-sided Premier League match 1-0 at White Hart Lane on Sunday.
Papiss Cisse scored both goals as Newcastle United continued their surprise push for a top-four finish in the Premier League on Sunday with a 2-0 victory over Liverpool, who had keeper Pepe Reina sent off late on.
His reflections on the origins of mass sparked a nearly five-decade, multi-billion dollar search for a subatomic particle, later known as the 'Higgs boson', which was thought to hold the key to understanding the nature of the universe.
Newcastle United striker Papis Cisse has split from his beauty queen girlfriend Rachelle Graham, and is looking to concentrate on football after a turbulent few months.
Bukayo Saka scored either side of halftime as Arsenal crushed second-bottom Burnley 5-0.
Manchester United were humbled 3-0 at home by Newcastle United in the League Cup fourth round
An intoxicating day of Premier League action on Saturday ended with leaders Manchester United beaten for the first time this season, title rivals Arsenal blowing a 4-0 lead and a record 41 goals across eight fixtures.
Arsenal will host Newcastle United in the outstanding League Cup third-round tie after the draw was made on Saturday.
Newcastle United's Moussa Sissoko says the Premier League was made for him after the France international midfielder began his career in England with two goals and an assist in his first two matches.
Spain manager Luis de la Fuente left Barcelona's 17-year-old defender Pau Cubarsi and midfielders Marcos Llorente and Aleix Garcia out of his 26-man squad
Newcastle United defender Stephen Taylor equalised on the hour to earn a 1-1 draw against Arsenal at home.
Chelsea missed the chance to effectively seal the Premier League runners-up spot after a late Steven Taylor header secured Newcastle United a 2-2 draw at Stamford Bridge on Sunday.
Jarrod Bowen and Mohammed Kudus' second-half goals gave West Ham a 2-0 win over Manchester United in the Premier League's early game on Saturday, as the Hammers briefly moved into the top six.