Harry Kane scored his 36th goal of the season but Bayern Munich let a second-half lead slip to draw 2-2 with Hamburg SV.
Galatasaray struck twice in extra time to end 10-man Juventus' brave fightback and reach the Champions League's last 16, progressing with a 7-5 aggregate victory.
Mbappe fires Real Madrid to the summit, Bayern lose at home and Dortmund stay in the title hunt.
Championship side Oxford United beat League Two's MK Dons on penalties after their match ended 1-1, while a couple of League One teams moved on, with Wigan Athletic beating Championship side Preston North End 1-0, and Port Vale defeating League Two's Fleetwood Town 1-0.
Stuttgart stumble to 1-1 against Union, miss out on top three
Real Madrid ended a turbulent week with a 2-0 LaLiga win over lowly Levante on Saturday courtesy of second-half goals from Kylian Mbappe and Raul Asencio.
Barcelona recovered from an early setback to secure a 3-1 victory over Deportivo Alaves in LaLiga on Saturday.
Inter edge Genoa to go top
Bayer Leverkusen have sacked manager Erik ten Hag after two league games in charge, the Bundesliga club said on Monday, with the weekend draw at Werder Bremen not enough to save the Dutchman's job.
Borussia Dortmund defenders Waldemar Anton and Almugera Kabar are doubtful for Friday's Bundesliga game against Bayer Leverkusen due to illness, coach Nuri Sahin said.
England captain Kane headed in either side of the break to take his league tally since joining Bayern in 2023 to 55 league goals, more than any other player in their first 50 games in the league's history.
A summary of Saturday's action in LaLiga, Bundesliga and Serie A.
Mainz 05's Lee Jae-sung scored either side of the break as the hosts stunned Bundesliga leaders Bayern Munich 2-1 on Saturday.
A summary of Saturday's action in the Serie A, Ligue 1 and Bundesliga
Bundesliga leaders Bayern Munich powered past third-placed Eintracht Frankfurt 4-0 with an impressive display of high-pressing football on Sunday.
Barcelona thrashed Real Betis 5-1 on Wednesday to book their spot in the Copa del Rey quarter-finals.
Bayern Munich earned a nervous 1-0 win at St Pauli thanks to a sensational 28-metre drive from Jamal Musiala to stay unbeaten.
Paris St. Germain's unbeaten start to their Ligue 1 season continued on Friday with a comfortable 3-1 win over Rennes at the Parc des Princes that saw Bradley Barcola score twice to keep them top of the standings.
Leverkusen's Schick scores hat-trick in comeback win over Heidenheim.
IMAGES from the UEFA Champions League matches played on Wednesday
Roundup of the matches being held across major football leagues in Europe on Sunday
Barcelona's Sergi Roberto and Robert Lewandowski struck just before halftime to give the league leaders a 2-0 home win over lowly Cadiz on Sunday in their pursuit of a 27th Spanish title.
Augsburg's victory lifted them out of the relegation zone into 15th place.
Gladbach dominated the first half and missed a string of chances, with Freiburg goalkeeper Alexander Schwolow denying Plea and Lars Stindl in quick succession as the home side defended desperately.
League leaders Bayern Munich demolished Hamburg SV 9-2 with four goals from striker Claudio Pizarro and two from Arjen Robben on Saturday to put one hand on the Bundesliga trophy with seven games to play.
Germany midfielder Ilkay Guendogan has been ruled out of Euro 2016 after sustaining a serious knee injury in training with Borussia Dortmund, the club said on Friday.
Bundesliga leaders Bayern Munich effortlessly cruised to a 1-0 victory at Hoffenheim on Sunday courtesy of a Mario Gomez goal that kept them on course for the title with a 17-point advantage at the top.
Runaway leaders Bayern Munich won 2-0 at VfL Wolfsburg on Friday with goals from Mario Mandzukic and Arjen Robben to move a massive 18 points clear at the top of the Bundesliga.
Mario Mandzukic scored one goal and created the other as Bundesliga leaders Bayern Munich pulled 11 points clear of their nearest title rivals with a 2-0 victory at VfB Stuttgart on Sunday.
India's friendly match against German football giant, Bayern Munich in January next year will be Indian legend Bhaichung Bhutia's "official farewell match", the AIFF said on Saturday.
Neighbours Manchester United and City recorded convincing wins to continue setting the pace in the Premier League but European champions Barcelona dropped points in La Liga. There were plenty of goals in Italy as the Serie A season finally got underway after a players' strike and German leaders Bayern Munich scored seven times in their match against Freiburg.
VfL Wolfsburg midfielder Kevin De Bruyne has been fined $22,644 for his foul-mouthed outburst at a ball boy.
Cologne, looking for their fourth straight league win, thought they had wrapped up the match played without spectators after early goals in each half.
Played behind closed doors, the result lifted Hertha one place up to 10th on 34 points from 27 games while promoted Union, who won the reverse fixture in November 1-0 thanks to a late penalty, stayed 12th on 30 points.
Bayer Leverkusen stayed in the hunt for a top-four finish in the Budesliga after two goals by striker Kai Havertz as well as one each by Mitchell Weiser and Kerem Demirbay helped them to a 4-1 win at struggling Werder Bremen on Monday. The result left Bayer fifth on 50 points from 26 games, one behind fourth-placed Leipzig and eight adrift of leaders Bayern Munich. Werder, who suffered a record-extending seventh straight home defeat, stayed 17th on 18 points from 25 matches.
Bundesliga club Schalke 04 have signed Manchester City defender Matija Nastasic on loan until the end of the season.
At least half a dozen players suffered injuries in Bundesliga, highlighting concerns about plunging straight into competitive action after a two-month stoppage without warmup matches.
Bayern come from behind to beat gutsy Mainz 2-1 and widen gap.
Italy striker Luca Toni scored twice to steer Bundesliga leaders Bayern Munich to a 2-1 victory over Bayer Leverkusen on Saturday.
Borussia Dortmund centre back Mats Hummels has told his club that he wants to join Bundesliga leaders Bayern Munich after the season ends.
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