The loss was the joint-heaviest defeat by a side already crowned Premier League champions. Arsenal were beaten 4-0 at Liverpool in 1997-98 in the game after they clinched the title.
IMAGES from the English Premier League matches played on Saturday.
Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter, at Anfield, on Sunday. All four goals came in the second half.
Claudio Bravo was pictured leaving Barcelona Airport on Tuesday and his expected move to Manchester City is likely to trigger the departure of England goalkeeper Joe Hart. The 33-year-old Bravo is set for a medical this week at the Etihad Stadium where he will team up again with Pep Guardiola, his former manager at Barca. The Spanish champions said on Saturday they had reached a "preliminary agreement with City" for the sale of the Chile captain.
Barring a monumental collapse Manchester City will win at least two trophies this season, but former England captain Alan Shearer believes European bragging rights are what the club's Abu Dhabi owners crave most.
The dynasty will only be built on European success, though, and after the quarter-final exit to Liverpool, Manchester City's owners, who want a gilded continental powerhouse to match United's global lustre, will demand it and back those demands with huge funding.
Liverpool raised the bar so high and enjoyed such a huge winning margin in claiming the English Premier League title last season it would be churlish to doubt their credentials for a repeat showing.
News that transpired on and off the football field.
Manchester City cannot afford another defeat on Tuesday at home to Barcelona, who thumped them 4-0 two weeks ago, having taken just one point from their last two Champions League Group C matches.
The Champions League quarter-final between Liverpool and Manchester City is one of the most anticipated games of the season pitting the Premier League's runaway leaders against the top scorers in Europe's elite competition.
Finances aside, though, there is an even bigger question mark hanging over Lionel Messi. Is he a fading force?
Images from EPL matches played on Wednesday.
Leroy Sane struck the winner as Manchester City beat Liverpool 2-1 in a gripping English Premier League clash.
"After feeling strange in the second half of the Burton game in September, I underwent a series of tests," he said.
This time Liverpool are at home, and victory would put them nine points clear.
Chelsea paid a heavy price for a 3-2 defeat at West Ham United as first Liverpool, then Manchester City, leapfrogged them in the English Premier League title race on Saturday, with City ending the day on top for the first time this season.
"The best team won, we struggled from the beginning and we couldn't deal with their long balls. Usually, you press the ball to win it, but this was different. They defended so deep and so well," City coach Pep Guardiola told the BBC.
Van Dijk was substituted early in the game when Everton goalkeeper Jordan Pickford made a reckless challenge in the box, which left Liverpool manager Juergen Klopp fuming.
The 37-year-old Mikel Arteta played for Arsenal from 2011 to 2016 before moving to Manchester City as assistant manager, where he won the Premier League twice.
Five facts about Tito Vilanova, who will take over as Barcelona coach from Pep Guardiola at the end of the season.
Manchester United manager Jose Mourinho has promised to show plenty of restraint and respect if he inflicts a first Premier League defeat of the season on his former side Chelsea on Saturday.
Manchester City barely got out of second gear as they easily beat bottom club Huddersfield Town to close the gap on Premier League leaders Liverpool to four points on Sunday.
Manchester City's Premier League title hopes were delivered a grievous blow on Sunday as Everton's inspired Romelu Lukaku and teenagers Tom Davies and Ademola Lookman made it another crushing afternoon for Pep Guardiola.
Liverpool manager Juergen Klopp is not about to change his team's trademark style against Champions League quarter-final opponent
Southgate said England had been forced to give players extra days' recovery and also tapered their training schedules as the country's hopes of qualifying for the Nations League finals were dashed after Sunday's 2-0 defeat by Belgium.
Lionel Messi is 34 goals short of becoming Barcelona's all-time top scorer after netting a hat-trick in the Champions League on Tuesday, and the only real question left is when he will achieve that accolade and not if.
Pep Guardiola's appointment at the high-flying Premier League club is certainly ill-timed, argues Bikash Mohapatra.
There were a few nerves at the end but Liverpool set up a Champions League semi-final with Spain's Villarreal after Roberto Firmino scored twice in a 3-3 second-leg draw with Benfica on Wednesday to ensure a 6-4 aggregate win.
The following are three talking points from the weekend's Premier League action:
City Football Group will be a 65 per cent majority stakeholder of the club, alongside existing shareholders, actor Ranbir Kapoor and Bimal Parekh, who will keep the remaining 35 per cent.
Images from the English Premier League matches played on Saturday.
On Sunday the Ukrainian Tennis Federation urged the sport's governing body the International Tennis Federation (ITF) to immediately expel Russia and Belarus from the organisation and ban Russia from team and individual tournaments. Also, athletes from Ukraine and other nations have called on the International Olympic Committee (IOC) to suspend Russia and Belarus and ban their athletes from events immediately.
Manchester City and Everton players took to the field wearing Ukrainian flags before their Premier League game on Saturday while there were anti-war messages at stadiums elsewhere following Russia's invasion of Ukraine.
Sky Sports said that the 31-year-old Argentine was on his way to City's training facility in his car when the accident occurred.
IMAGES from the English Premier League matches played on Sunday.
City will look to extend lead against United at Old Trafford
Manchester City secured a record 15th straight victory in all competitions with a 3-1 win at Championship side Swansea City in the FA Cup fifth round on Wednesday.
Yaya Toure's agent says the Manchester City midfielder plans to stay and fight for his place despite being left out of their first game of the season. The Ivorian, who played under new manager Pep Guardiola when the pair were at Barcelona, was omitted for Saturday's narrow 2-1 win over Sunderland in City's Premier League opener.
Images from the UEFA Champions League group matches played on Tuesday night
Images from the Premier League matches played on Sunday.