Williams, a record 23-times Grand Slam champion, will be returning to the All England Club for the first time since giving birth to her daughter last September.
It was the Russian's first competitive match since she withdrew from the St Petersburg Open in January.
For a seven-time champion who is a month shy of his 35th birthday, and is known to have a dodgy back, fate could not have dealt Roger Federer a better hand this week as he became the first, and so far only, man to reach the Wimbledon fourth round.
Venus Williams accused Wimbledon officials of discriminating against its women champions and wants "equality" when it comes to scheduling matches on its two biggest showcourts.
Australia's Bernard Tomic thinks he is playing some of the best grasscourt tennis of his career and is in a good place off the court as he heads into the Wimbledon championships main draw for the seventh time.
Angelique Kerber feels vindicated that she now belongs at the upper echelons of the women's game after four years of consistency helped her into her first Grand Slam final at the Australian Open on Thursday.
Images from the matches played at the All England Lawn Tennis and Croquet Club, in Wimbledon, London, on Monday.
If it is so dark that Hawkeye stops working, then matches should be called off at Wimbledon, Roger Federer said.
The 23-year-old says the points and calculations are far from her mind and it is the big events such as Wimbledon and next month's US Open that fire her up.
'I guess you would have laughed if I told you I was going to win two slams this year'
Serena Williams once featured among Heather Watson's bedroom posters but after the Briton almost ran her idol out of Wimbledon.
'I would say winning the US Open has helped me for all these grand slams I have played so far, and I believe the rest of my career' 'It's great for me to hear that even he, and a lot of players around, even ex-players, when they were looking before the tournament started, that they were seeing me as a player that could go quite deep (into the tournament)'
The 39-year-old German, awarded a wildcard for his 16th and final appearance at the All England Club, had to accept his body was "not cooperating anymore" as he slumped to a 6-2, 3-6, 6-3, 7-5 first-round defeat by Belgian qualifier Ruben Bemelmans.
Federer begins the pursuit of a record eighth Wimbledon title and a record 85th match win at the grass court major; Djokovic hoping to curb dismal slide
The Swiss three-time grand slam champion was out-gunned by 21-year-old Medvedev, who had the Centre Court crowd on their feet as he pulled off a dazzling array of winners to wrap up a 6-4, 3-6, 6-4, 6-1 victory on his first Wimbledon appearance.
News of all that's transpired on and off the tennis courts.
'This was the first time that I played points and that was too much for me today'
Yet to feel completely at home on the Wimbledon lawns, Stan Wawrinka became the latest player to jump on the super-coach bandwagon by joining forces with former All England Club champion Richard Krajicek this month. Krajicek knows a thing or two about playing at the heartland of grasscourt tennis as not only did he triumph in 1996, he was also the only man to have beaten seven-times champion Pete Sampras at Wimbledon between 1993 and 2000.
Petra Kvitova produced a majestic performance to end Eugenie Bouchard's hopes of becoming the first Canadian to win a Grand Slam title with a 6-3, 6-0 win in the Wimbledon final on Saturday.
Sunday's four-set verdict over Roger Federer was the 28-year-old's 200th singles victory in a major tournament, making him only the sixth player to achieve the feat.
The daughter of two lawyers and a former waitress received their last orders at the Wimbledon on Tuesday when Madison Keys and Timea Bacsinszky missed out on a great opportunity to set up a semi-final date.
Former American World No 1 Lindsay Davenport, a winner of three Grand Slam singles titles, headlined the list of nominees up for induction into the International Tennis Hall of Fame.
The Scot credits Mauresmo for guiding him through some testing times and contrasted the Frenchwoman's approach to some of her predecessors.
"There is nothing very negative. I won a tournament last week. This week I lost an opportunity, but, my feeling, my thoughts are no different today than yesterday.
Australian great Rod Laver is as impressed as anyone while watching Rafael Nadal tear into the fourth round of Wimbledon on Saturday to stay on track for a third title.
IMAGES from the matches played on Day 4 of the Wimbledon Lawn Tennis Championships at All England Lawn Tennis and Croquet Club on Thursday
Milos Raonic, the finalist at Wimbledon this year, and women's world number five Simona Halep of Romania have pulled out from next month's Rio Olympics due to fears over the Zika virus.
Serena Williams was forced to go on the attack once again to defend equal prize money after she reached a ninth Wimbledon final in a new record time. The world number one blasted Russia's Elena Vesnina off Centre Court in just 48mins 34sec, the fastest ever semi-final at the All England Club. Vesnina earned 500,000 ($649,000) by making the last four.
Slowly but surely Andy Murray is scratching his name alongside the all-time grasscourt greats on Wimbledon's hallowed lawns.
The peak remains tantalisingly close for Serena Williams but negotiating the final incline to a record-equalling 22nd Grand Slam singles title is proving the trickiest of all.
An air of calm descended at Wimbledon on 'Tranquil Thursday' as Novak Djokovic and Serena Williams avoided the trail of destruction that had decimated the field at the All England Club on day three of the grasscourt major.
Top seed Roger Federer will challenge for a ninth Halle Open title after reaching the Wimbledon warm-up event final with a 6-4 7-6(5) victory over rising Russian talent Karen Khachanov on Saturday.
If there is a new member of the grand slam champions' club this weekend, nobody should be surprised -- the conditions at this year's sodden, chilly French Open suit the underdog.
I'd love to win Wimbledon and I think it's possible, says Roger Federer.
Former Wimbledon champion Anne Jones was among British sports personalities included in the United Kingdom's New Year's honours list on Monday.
It was a clearly deflated Rafa Nadal who admitted he has no idea whether he can ever reproduce the form that helped him win two Wimbledon titles after maverick Dustin Brown inflicted a fourth successive embarrassment.
A summary of the second day's play at the US Open.
Second seed Novak Djokovic complained of a "hole" on Centre Court at Wimbledon after beating Adrian Mannarino in his delayed fourth-round match on Tuesday.
Although he had beaten Nadal 12 years ago at Wimbledon, few gave Luxembourg's Muller a chance on Monday against the fourth seed and French Open champion. 'This is definitely the biggest victory since then, since I came back, especially at that stage of a grand slam, playing one of the guys who is dominating the tennis this year again. Definitely the biggest win'
Spaniard Garbine Muguruza's relationship with grasscourt tennis has not been smooth but it has blossomed so spectacularly.