The 32-year-old, who captained the Dutch to third place at the 2014 World Cup in Brazil, has been overlooked by coach Danny Blind, who is not convinced about his form with Fenerbahce.
Updates from around the different clubs in the English Premier League
Rafa Benitez's much-changed side with a youthful streak had looked set to coast through when Sean Longstaff's deflected shot put them ahead after 56 seconds and Callum Roberts volleyed home a second four years since his only other Newcastle appearance.
Newcastle's worries deepened as they now remain at 19th in the table.
As the Premier League resumes following the international break all eyes will be on Cristiano Ronaldo's homecoming party at Old Trafford on Saturday, with the Portuguese international set to resume his Manchester United career after 12 years away.
Newcastle United fans reacted with fury on Thursday after the club announced it was dropping the 119-year-old name of its ground St James' Park and calling it the Sports Direct Arena instead.
The Portuguese coach was reported to have directed an insult in his native language towards a camera which was live tracking him down the touchline after his side's 3-2 comeback win at Old Trafford.
Fans return to English grounds, but told not to celebrate goals too much.
Images from EPL matches played on Saturday.
West Brom, relegated from the Premier League last season, made 11 changes from the side that won at the weekend in the Championship and had five players -- including goalkeeper Alex Palmer -- making their debuts.
Liverpool added on their website that the furloughed staff would continue to receive 100% of their salaries. Several English top-flight clubs, such as Tottenham Hotspur, Bournemouth and Newcastle United, have already put non-playing staff on furlough, with football's return in England contingent on medical guidance and government support.
Atletico Madrid have temporarily cut players' and coaches' wages by 70% in order to cope with the financial impact of the coronavirus pandemic, but guaranteed a full salary for their other employees, the Spanish club said
Bournemouth have furloughed staff while top executives and coaches have taken voluntary pay cuts to help ease the financial impact of the coronavirus crisis on the south-coast side, the Premier League club said on Wednesday.
Norwich City and Newcastle United have been charged by the Football Association following a scuffle between Bradley Johnson and Loic Remy during a Premier League match last week.
With sports events around the world suspended because of the coronavirus pandemic, football clubs and leagues have been discussing pay cuts with players to help them make it through the crisis.
"We are all hopeful that the surgery I have had will ensure I don't have any repeat of the condition in the future."
"The best team won, we struggled from the beginning and we couldn't deal with their long balls. Usually, you press the ball to win it, but this was different. They defended so deep and so well," City coach Pep Guardiola told the BBC.
Former Ivory Coast midfielder Cheick Tiote collapsed and died in training with his Chinese club on Monday, his agent confirmed.
Manager Steve McClaren called for more of the same after Newcastle United beat Tottenham Hotspur on Sunday to put some daylight between themselves and the relegation zone, but stopped short of describing the win as a turning point in their season.
Dimitri Payet struck a brace for the Hammers against a tired Newcastle, whose players had to trudge the last mile to West Ham United's stadium after their team coach became stuck in London's rush-hour traffic before Monday's Premier League fixture.
Rui Patricio saved three penalties as Wolverhampton Wanderers defeated English Premier League champions Manchester City to claim the Premier League Asia Trophy 3-2 in a penalty shootout.
Newcastle United named Alan Pardew as their 12th manager in the last 13 years on Thursday in place of Chris Hughton who was controversially sacked this week.
CR7 started the game against the Toons in his second debut at Old Trafford.
IMAGES from the English Premier League matches played on Wednesday.
Chelsea may have restored some breathing space over Manchester City with a 2-0 win over Newcastle United on Saturday but they have not regained the form that made them runaway title favourites earlier in the season.
The club said in a statement that they will observe a period of self-isolation in accordance with league and UK Government protocols on quarantine.
Images from Saturday's English Premier League matches.
Manchester City shook off the impact of a COVID outbreak in their ranks to outclass Chelsea 3-1 at Stamford Bridge
'I can't give you a time but we will get there. We have given ourselves a big, big uphill task to get in the top four, never mind the top six'
The English Premier League is not the same product with fans barred from stadiums but clubs have no choice but to adapt in challenging times, Newcastle United boss Steve Bruce said on Friday. The English top-flight season restarted on Wednesday with two matches after a 100-day hiatus due to the COVID-19 pandemic, but access to stadiums has been restricted to squads, coaching staff and necessary personnel only.
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.
Images from Sunday's action in the Premier League.
Former England and Newcastle United captain Alan Shearer will manage Newcastle United for the remainder of the season, according to television reports on Tuesday.
A summary of Saturday's action in the Premier League.
71-year-old Sven-Goran Eriksson won 18 trophies with various clubs in Sweden, Portugal and Italy, between 1979 and 2000, and became the first manager to win league-and-cup doubles in three countries.
Liverpool manager Juergen Klopp took exception to Frank Lampard's comments after the Chelsea boss labelled the Premier League champions 'arrogant' following a touchline spat during Wednesday's 5-3 win at Anfield. At his news conference ahead of Sunday's trip to Newcastle United for their final game of the season, Klopp said Lampard had a lot to learn to keep his emotions in check after the fulltime whistle.
The 41-year-old has made 640 appearances in Serie A, within striking distance of the 647-game record of AC Milan defender Paolo Maldini. Buffon began his career at Parma before moving to the Turin club in 2001.
The 'turbulent situation' at Newcastle United has forced Reliance Communications to shift focus to English Premier League side Everton, media reports said in London on Sunday.
A preview of the line-up action in the English Premier League
Anil Ambani group firm Reliance Communications on Monday said news reports that it was acquiring the English Premier League club Newcastle United for an estimated 260 million pounds were false and baseless.
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