A look at the 10 landmark matches from the 20-times Grand Slam champion's career.
Serena Williams was fined $10,500 on Sunday by officials at the US Open and could face further sanctions after an investigation was launched into her angry outburst during her semi-final defeat by Kim Clijsters.
While trying to surpass Margaret Court's record of 24 Grand Slam titles might be one of the reasons she pushed herself to get back on court despite all her complications in childbirth, she also wants to see if she recover her pre-pregnancy form.
Serena returned from a maternity break to lose 6-2, 3-6, 10-5 to the 20-year-old Latvian.
Summary of sports events and persons who made news on Saturday.
SSerena Williams swept past Anastasija Sevastova 6-3, 6-0 on Thursday and into the final of the US Open to sit one win away from a record-equalling 24th Grand Slam title.
Serena William powered her way to within two victories of a seventh US Open title on Tuesday and while she refused to look ahead there are many willing to do it for her, and what they see is a suddenly open path to a 24th Grand Slam.
Germany's experienced Angelique Kerber stands in the way of the 36-year-old American and an eighth, and arguably most impressive, All England Club singles crown which would see her match Margaret Court's all-time record of 24 Grand Slam titles.
World No 1 Serena Williams has backed Danish tennis star Caroline Wozniacki's accusations of ' sexist scheduling' at the Wimbledon Championships.
Mavericks won the men's doubles and men's legends singles rubber, but the Slammers clinched the women's singles, mixed doubles and men's singles to come out trumps.
Agnieszka Radwanska showed why she should be considered among the favourites for the Australian Open later this month by beating world number one Serena Williams in the final of the Hopman Cup in Perth on Saturday.
Serena Williams and her sister Venus are in preliminary talks to become part-owners of the NFL's Miami Dolphins, the 11-time grand slam winner confirmed on Wednesday.
Tennis sensation Maria Sharapova yet again rules the Forbes' list of highest-paid female athletes.
Serena Williams' relaxed outlook on life spilled over even in defeat on Saturday when she appeared to be almost as happy that Angelique Kerber had won her first Grand Slam final as the German herself.
Serena Williams underlined the difference in class and power between her and the rest of the women's field with a 6-0, 6-4 demolition of fourth seed Agnieszka Radwanska on Thursday to reach her seventh Australian Open final.
Reigning champion Serena Williams ramped up the power in the second set to vanquish fifth seed Maria Sharapova for the 18th match in a row and reach the semi-finals of the Australian Open with a 6-4, 6-1 victory.
Serena Williams crashed out of the Auckland Classic after fellow American Madison Brengle pulled off a 6-4, 6-7(3), 6-4 upset in a see-saw second round contest.
LeBron James has overtaken Michael Jordan as the United States' most popular athlete, according to a Harris poll. Serena Williams was voted America's favorite female athlete.
Those not familiar with seeing Swiatek close up can expect to see her sliding on Wimbledon's grass, as she does on the clay
While the United States has the highest number of confirmed COVID-19 cases in the world, New York seems to have a better handle on the virus and reported less than 5,000 new cases last week.
Such has been Serena Williams's iron-fisted dominance of women's tennis that the American is one Wimbledon title away from achieving a 'Serena Slam' and halfway towards completing a rare calendar Grand Slam.
Making her Grand Slam comeback in Paris following the birth of her daughter Alexis Olympia last September, Serena Williams will renew her fierce on-court rivalry with Maria Sharapova on Monday when they meet in a highly-anticipated fourth-round showdown at the French Open.
Top ranked Serena Williams won her third consecutive U.S. Open women's championship when she defeated Denmark's Caroline Wozniacki 6-3, 6-3 on Sunday.
An ailing Serena Williams stayed on course for a 20th grand slam singles title as she came back from the brink to reach the final of the French Open with a 4-6, 6-3, 6-0 win against Swiss power hitter Timea Bacsinszky on Thursday.
Serena Williams said the latest chapter in her tennis life was "just beginning" on Saturday after seeing her hopes of a record-equalling 24th Grand Slam title dashed in the Wimbledon final.
The 36-year-old has been practising hard on the grass and few would bet against her becoming the first mother to win the title since Evonne Cawley 38 years ago.
Serena Williams crashed out of the US Open after losing in the semi-final to Karolina Pliskova costing her a shot at a 23rd Grand Slam title and resulted in her losing her record 187th straight week at number one.
The tennis ace knocked our socks off with her stunning Serena Williams Signature Statement Collection. Take a look!
Nastase was also heard to call her and British No. 1 Johanna Konta "f****** b******" during the Davis Cup competition being held in Constanta, Romania.
Coach Patrick Mouratoglou claimed Serena Williams' fitness had since gone up a notch and Margaret Court's all-time record of 24 Grand Slam singles titles may well be in peril at the Australian Open.
Images from the women's singles quarter-finals at Wimbledon on Tuesday.
World number one Serena Williams slammed Shamil Tarpishchev for using "extremely sexist, racist and bullying" comments after the Russian Tennis Federation (RTF) president described her and sister Venus as the "Williams brothers".
Serena Williams said it was a 'great feeling' to surpass Steffi Graf as the most prolific grand slam champion of the open era at the Australian Open on Saturday and was not prepared to put a number on the haul of titles she might end up with.
The cartoon has been blasted by numerous athletes, celebrities, journalists and activists
US Open aces Wimbledon for top Grand Slam prize money.
Naomi Osaka faces a far more daunting task: Playing against her hero in the US Open final.
Maria Sharapova and world No 1 Serena Williams haven't played each other at the Wimbledon Championships since their Round of 16 clash in 2010.
Even the Parisian stormclouds cleared for Serena Williams on Tuesday, as the new mother's baby steps back to Grand Slam tennis became a stride into the second round of the French Open.
The Pole, who won the crown in 2020 and hasn't lost since February, matched Serena Williams's winning run from 2013 in the process, having now lost only two sets in her last four tournaments.
Tennis players and venues stick to strict guidelines aimed at minimising health risks.
