Jose Mourinho admitted that Sunday's 2-0 defeat to Arsenal means it will now be "impossible" for Manchester United to finish in the top four.
Having headed into the match tied on 47 league goals with West Ham's former stalwart Paolo Di Canio, Antonio was delighted to have surpassed the Italian as he celebrated by lifting a cardboard cut-out of himself at the side of the pitch.
The Spaniard became the most successful foreign manager in the history of English football, after clinching his fourth Premier League crown.
Manchester United striker Anthony Martial has put to bed all speculations about him leaving Old Trafford this summer.
Manchester United's new manager Jose Mourinho made peace with Bobby Charlton as he met the Old Trafford icon at the club's Carrington training ground.
Edinson Cavani and Anthony Martial struck late goals as Manchester United claimed a scrappy 2-0 victory over Everton at a bitterly cold Goodison Park,
The 24 sides through from the group phase join the eight third-placed finishers in the Champions League in Monday's draw, including Manchester United and Ajax Amsterdam.
But Mourinho grabbed the attention of photographers on the sideline as his frustration at his team's showing forced a range facial expressions that would give 'Mr Bean' serious competition. Scroll down to see the 'varied faces' of Mourinho from Tuesday night's match...
United finished second last term, their best placing since the 2013 title win in Alex Ferguson's last season in charge, but the Red Devils were a massive 19 points behind champions Manchester City and never truly in contention.
Striker Ibrahimovic and defender Rojo are back training with the first team after suffering serious knee ligament injuries last season while midfielder Pogba has shaken off a hamstring problem that has kept him out of the side since September.
The game at Huddersfield is the first meeting between the clubs since 1972 and the Yorkshire side have not won one since 20 years before that, in March 1952.
A round-up off all transpired on and off the football pitch
Manchester United's injured players can utilise the international break to regain full fitness while key squad members can get much-needed rest, manager Jose Mourinho has said.
Manchester United striker Romelu Lukaku, the subject of criticism from the club's fans, should be "untouchable", his manager Jose Mourinho said.
Manchester United manager Jose Mourinho has sarcastically labelled himself the worst manager in the history of football after he faced criticism following a recent slump in form.
'Don't get that worried about what the manager's said about you... you get out there and play. You can follow it up after the match but when the game's going on liven up. Play with pride, play with energy, play with spirit.'
News of all that's transpired on and off the football field
Manchester City's eight point advantage after 11 games is leading to talk of the Premier League title race being over in November, but as Manchester United manager Jose Mourinho noted - English football has a habit of throwing up surprises.
Jose Mourinho is expected to be named Manchester United's new manager either later, in Thursday, or Friday, after the tangled issue of who owns his name - and, crucially, is licensed to exploit it commercially - is resolved.
England striker Jamie Vardy has likened the mood in the squad ahead of the World Cup to that of Leicester City's Premier League title-winning campaign.
Manchester United midfielder Paul Pogba remained guarded about his future at the English Premier League club on Thursday following Spanish media reports linking him with a move to Barcelona.
I'm not happy with just fighting for fourth, I want to fight for trophies, says manager Jose Mourinho
A clash between supposedly the two most expensive lineups in history overseen by two of the most decorated coaches will end the phoney war and ignite the Premier League season for real when Manchester United host Manchester City on Saturday.
Mourinho hits out at Man United's 'crazy' fixture congestion
Liverpool's bandwagon rolled on as they crushed Merseyside rivals Everton 5-2
Bayern Munich thrashed Bayer Leverkusen 5-1, while Barcelona came from behind to beat Valencia 3-1 in LaLiga at Camp Nou on Sunday.
Neymar has been included in Paris St Germain's squad for Wednesday's Champions League game against Bayern Munich after recovering from a foot injury, coach Unai Emery said on Tuesday.
Speculation about Paul Pogba's future at Manchester United continues to mount amid reports in the British media that the midfielder is afraid he will be punished if he says the wrong thing.
Manchester City withdrew from the battle to secure the services of Arsenal's Chilean forward Alexis Sanchez, leaving Jose Mourinho's Manchester United as the most likely destination for the 29-year-old.
Chelsea assistant coach Marco Ianni was charged with improper conduct by the Football Association on Monday after his exuberant celebrations in front of the Manchester United bench sparked an altercation with Jose Mourinho.
Manchester United might have left themselves too much ground to make up in the Premier League title race as they trail leaders Chelsea by 11 points after 13 games, according to their manager Jose Mourinho.
Manchester United manager Jose Mourinho will not stoke his rivalry with fellow new recruit Pep Guardiola at Manchester City next season because it could damage his team's Premier League title hopes.
Manchester United midfielder Paul Pogba will miss his side' s Premier League clash against Southampton on Wednesday as he has to attend his father's funeral.
Bastian Schweinsteiger has been left out of Manchester United's Europa League squad by coach Jose Mourinho, as the midfielder continues to be marginalised at the club.
Mourinho wants to see Pogba's World Cup focus at Man United
News of all that's transpired on and off the football field
Jose Mourinho said on Monday he would step up Manchester United's pursuit of Gareth Bale if the Real Madrid winger was left out of the starting line-up in Tuesday's European Super Cup between the Red Devils and the Champions League holders.
'We can work and fight for it' 'Yes, they had much more of the ball. Yes, they had that apparent control of the game but the biggest save is the double save of their goalkeeper and the biggest decision of the game is the unlucky decision of Michael (Oliver)'
Manchester City chalked up yet another victory to maintain their stranglehold of the Premier League title race but pursuers Manchester United and Leicester City both secured important wins to enhance their top-four bids on Sunday.
Guus Hiddink is set to take over as Chelsea manager until the end of the season.