Real moved to 57 points, two ahead Girona and 10 clear of Atletico Madrid and Barcelona.
Marco Asensio's strike earned Real Madrid a 1-0 win over Espanyol to send them top of La Liga and Thomas Lemar scored his first goal for Atletico Madrid in a 2-0 victory at Getafe on Saturday.
Brazilian teenage striker Endrick came off the bench to score two goals in extra time and help Real Madrid rescue a hard-fought 5-2 win over Celta Vigo.
Barcelona thrashed Real Betis 5-1 on Wednesday to book their spot in the Copa del Rey quarter-finals.
Cristiano Ronaldo netted his 18th and 19th La Liga goals of the season as Real Madrid survived some late pressure to win 3-2 at city rivals Getafe on Monday and trim the gap to leaders Barcelona back to two points.
Athletic Bilbao forward Urko Vera netted his first La Liga goal deep into added time to snatch a 2-2 draw for the Basque club at Getafe on Monday.
The victory saw the unfashionable Madrid club tighten their grip on the coveted fourth spot in the table by moving on to 58 points after 36 games, three points clear of nearest challengers Sevilla, who lost to Leganes on Friday.
Brazilian ace Ronaldo returned from injury to give Real Madrid a 1-0 victory in the Primera Liga.
Lionel Messi notched up his 35th league goal of the season as an understrength Barcelona strolled to a crushing 6-1 home win against Getafe that put them 12 points clear at the top of La Liga on Sunday.
Lewandowski strike gives Barcelona 1-0 win over Alaves
Barcelona's Lionel Messi, Luis Suarez and Neymar motored past 100 goals for the season.
Cristiano Ronaldo ended a barren scoring run in La Liga by striking late to give Real Madrid a 2-1 win at neighbours Getafe on Saturday, preventing what would have been a costly and embarrassing draw for the Spanish and European champions.
Kylian Mbappe was in inspired form, scoring twice to guide Real Madrid to a comeback 4-1 win over visitors Las Palmas on Sunday.
Atletico Madrid slipped three points behind second-placed Real Madrid after having two players sent off in a 0-0 draw at Getafe in La Liga on Sunday.
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Sevilla were on course for a place in the King's Cup semi-finals after crushing Deportivo Coruna 3-0 at the Riazor in their last-eight first leg match on Wednesday.
Leaders Barcelona survived red cards for Gerard Pique and Rafael Marquez to complete a 2-1 victory over Getafe in La Liga on Saturday while Real Madrid kept pace with a 3-0 win at home to Espanyol.
Barcelona snatched a late 2-1 win at Getafe with Paulinho's strike sending them seven points clear of arch-rivals Real Madrid at the top of La Liga.
Getafe scored a 1-1 draw at Bayern Munich on Thursday to improve their hopes of reaching the UEFA Cup semi-finals in their debut European season. Bayer Leverkusen were routed 4-1 at home by Russian champions Zenit St Petersburg, while Fiorentina were held to a 1-1 draw at home by PSV Eindhoven and a bad-tempered clash in Glasgow ended goalless between Rangers and Sporting.
Alvaro Negredo struck in stoppage-time as stuttering Valencia won 2-1 against his former club Sevilla on Sunday to earn coach Pako Ayesteran victory in his first home game in charge since succeeding Gary Neville.
Striker Aduriz opened the scoring in the sixth minute at the San Mames with a trademark header before midfielder Garcia, who joined from Atletico Madrid last month, nodded in a second in the 24th minute.
Real Madrid's Jude Bellingham again proved the match-winner as he struck in added time to snatch a 2-1 victory over Getafe as the Spanish giants made their home debut in La Liga this season.
Barcelona received a welcome boost on Tuesday when forward Lionel Messi was given the all-clear by medical staff and included in the squad for Wednesday's King's Cup last 16, first leg at home to Getafe.
Betis's Chimy Avila hit the post with an acrobatic volley one minute later and both teams wasted several chances for the winner late on.
A round-up of European football news over the weekend.
'We were happy with the win because we played a great game until the 88th minute, when two lapses in concentration led to two goals and we had to suffer a bit more than we should have.'
Images from Sunday's action in LaLiga and Serie A.
Barcelona closed to within two points of leaders Real Madrid after thumping Levante 5-1.
Real Madrid stayed hard on the heels of leaders Barcelona when in-form striker Karim Benzema scored to set them on their way to a 2-1 win at battling city rivals Atletico in La Liga on Saturday.
Real Madrid extended their dominance over city rivals Atletico and maintained their one-point lead at the top of La Liga when Ricardo Carvalho and Mesut Ozil scored in a comfortable 2-0 home win on Sunday.
Man City to face Spurs in League Cup
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Real Madrid extended their unbeaten run to 25 matches and rejoined Barcelona and Atletico Madrid at the top of La Liga when Jese, Karim Benzema and Luka Modric scored in a 3-0 win at Getafe on Sunday.
Real Madrid paid for defensive mistakes as they were held to a 3-3 draw at lowly local rivals Rayo Vallecano on Saturday.
Valencia continued their solid start to La Liga and climbed to second when recent Spain recruit Paco Alcacer set them on their way to a 3-0 win at Getafe on Monday.
IMAGES from football matches played across Europe on Wednesday.
Messi beat seven players, covering 48 metres in 12 seconds, taking 10 touches with his left foot and three with his right before finding the net.
Leaders Barcelona played out a second straight 0-0 draw in LaLiga after mid-table Getafe battled for a home point in a hard-fought game on Sunday.
Vinicius Jr came off the bench to score once and set up another goal to steer champions Real Madrid to a 4-1 fightback victory over Espanyol.
News of all that's transpired on and off the football field
