Liverpool's first loss of the season means they cannot finish the campaign unbeaten to match Arsenal's 'Invincibles' of 2003-04.
Images from the EPL matches played on Saturday
Arsenal has scored 10 goals in 11 league games this season to find themselves 15th in the Premier League
Mason Greenwood's late winner earned Manchester United a 1-0 win at wasteful Wolverhampton Wanderers in the Premier League on Sunday, breaking the record for the longest unbeaten away run in English Football League history in the process.
TThe switch to five subs - up from three - brings the Premier League in line with other major competitions in Europe.
Jose Mourinho's side had paid lavish sums to bolster key areas by this time last year but, having claimed the title at a canter, the motto of this transfer window seems to be: if it ain't broke, don't fix it.
Chelsea is currently at the fourth place in the Premier League standings with 63 points from 37 matches.
Liverpool manager Juergen Klopp took exception to Frank Lampard's comments after the Chelsea boss labelled the Premier League champions 'arrogant' following a touchline spat during Wednesday's 5-3 win at Anfield. At his news conference ahead of Sunday's trip to Newcastle United for their final game of the season, Klopp said Lampard had a lot to learn to keep his emotions in check after the fulltime whistle.
Manchester City moved 17 points clear of the pack with a 3-0 win at Fulham on Saturday
Chelsea remain in fourth place, and are two points off third-placed Leicester City who have a game in hand.
IMAGES from the Premier League matches played on Sunday.
Manchester City showed that their weekend derby loss was a blip as Kevin de Bruyne and Riyad Mahrez both scored twice in a 5-2 win over Southampton
A stoppage time goal by a heavily-bandaged Martin Skrtel spared Liverpool another deflating defeat as they drew 2-2 at home to Arsenal in the Premier League.
Images from the English Premier League matches played on Sunday.
Chelsea moved into the Premier League's top four as Mason Mount's superb first-half goal earned them a 1-0 win at champions Liverpool who suffered a club-record fifth straight home league defeat on Thursday.
Aston Villa returned to winning ways in stunning fashion as Ollie Watkins scored twice in a 3-0 away thumping of an abject Arsenal in drizzly north London on Sunday.
Images from English Premier League matches played on Sunday.
He has been rumoured to join Barcelona in the summer transfer window.
The Reds have won 28 of their 31 Premier League matches this season.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Phil Foden and Riyad Mahrez scored two goals apiece as the hosts showed their impressive strength
Manchester City defender Eric Garcia has been released from hospital after he was injured in a collision with goalkeeper Ederson in their 3-0 win against Arsenal, the Premier League club said on Thursday. Garcia, 19, collided with the Brazilian goalkeeper late in Wednesday's game and received treatment for several minutes before being carried off on a stretcher and taken to the Manchester Royal Infirmary Hospital for further tests.
A summary of Saturday's matches in the Premier League.
Chelsea slipped up in their push for a Champions League spot when they lost 1-0 at home to Arsenal in the Premier League on Wednesday with Emile Smith Rowe's first-half goal settling the London derby after a defensive mix-up by the hosts.
The government last month opened the door for elite sport to resume and the Premier League said it would restart its season on June 17.
Should Manchester United win their next two games, the gap will be cut to four points and while only a collapse of astonishing proportions would deny Manchester City the title.
Chelsea opened up a six-point lead at the top of the Premier League despite being held to a 1-1 draw against top-four hopefuls Southampton in an absorbing game at Stamford Bridge on Sunday.
West Brom's Dawson is villain and hero as Spurs' chances at League title fades; Leicester now need just one win from three games to claim EPL crown
Four players tested positive for coronavirus in the latest batch of tests conducted by the English Premier League and announced on Wednesday. Russian Premier League club Lokomotiv Moscow said on Thursday that four of its players had tested positive for the novel coronavirus.
Solskjaer is also hoping to keep hold of striker Odion Ighalo until the end of the season.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
Images from Sunday's action in the Premier League.
IMAGES from Premier League matches played on Sunday.
The Premier League's 'Project Restart' envisages a return to play in June, once given the green light from government, with the remaining 92 matches held behind closed doors at neutral venues.
Images from the EPL matches played on Sunday
Manchester City shook off the impact of a COVID outbreak in their ranks to outclass Chelsea 3-1 at Stamford Bridge
Chelsea are banking on a lavish shopping spree to give them more bite up front and much-needed solidity in defence after coach Frank Lampard spent last season relying heavily on a crop of inexperienced home-grown players.
Unlike the Champions League, Premier League referees have so far refused to take a second look at decisions on pitchside monitors
Liverpool raised the bar so high and enjoyed such a huge winning margin in claiming the English Premier League title last season it would be churlish to doubt their credentials for a repeat showing.
Ben Johnson and Tomas Soucek scored second-half goals as West Ham United twice came back from a goal down to earn a 2-2 draw at home to Brighton and Hove Albion in the Premier League on Sunday.