Tottenham Hotspur lost their cool and their Premier League title hopes as they let slip a two-goal lead at Chelsea to draw a stormy London derby 2-2 on Monday.
Southgate said England had been forced to give players extra days' recovery and also tapered their training schedules as the country's hopes of qualifying for the Nations League finals were dashed after Sunday's 2-0 defeat by Belgium.
Images from Saturday's action in the English Premier League.
Images from EPL matches played on Saturday.
Chelsea extended their impressive turnaround under new coach Thomas Tuchel with a 2-0 home win over in-form Everton on Monday as Kai Havertz played a key role in both goals on his return to the starting 11.
United are four points behind fourth-placed Arsenal, with a game in hand, as they search for a way into the top four and a place in next season's Champions League.
Manchester United's winless run continued but they gave under-fire coach Louis van Gaal crumbs of cheer with a committed display in an entertaining 0-0 draw with Chelsea while Arsenal went top of the table on Monday.
A dreadful defensive error from Arsenal's Granit Xhaka gifted Burnley an equaliser as the sides drew 1-1 at Turf Moor in the Premier League on Saturday.
Images from the EPL match played between Manchester United and Southampton on Monday.
Images from the English Premier League matches on Saturday.
Arsenal turned around its recent poor form to beat Leicester 3-1 on Sunday
Mohamed Salah hit a hat-trick as Liverpool humiliated Manchester United, romping to a stunning 5-0 victory at Old Trafford in the Premier League on Sunday that leaves Ole Gunnar Solskjaer's future in serious doubt.
Wolves midfielder Leander Dendoncker then hit the post with a powerful shot before Portuguese winger Podence made it 2-0, meeting Pedro Neto's cross from the right with a superb cushioned volley in the 27th minute.
Manchester United enjoyed perhaps their finest performance.
The rumblings of discontent from Righteous Europe over Qatar's admittedly appalling human rights record can only be viewed as deeply disingenuous and phoney, argues Kanika Datta.
Goalkeeper Alisson Becker scored a stunning header in the fifth minute of stoppage-time as Liverpool snatched a 2-1 victory at the death against relegated West Bromwich Albion at The Hawthorns on Sunday.
Roberto Firmino scored twice as Liverpool boosted their hopes of Champions League football next season
Images from the EPL matches played on Sunday
Antonio Conte spent the immediate aftermath of Chelsea's title-winning 1-0 victory at West Bromwich Albion on Friday being bounced skywards by his players but once back on terra firma his mind was already focusing on the next target -- the double.
Liverpool's Mohamed Salah ended his Premier League goal drought in style by scoring twice as the champions raided the capital again to crush West Ham United 3-1 on Sunday.
The decision comes after the game's rule-making body IFAB last month gave the go-ahead for trials of additional 'concussion subs'.
De Bruyne out for up to six weeks due to injury, says Guardiola.
Images from the English Premier League matches played on Saturday.
Arsenal snatched a dramatic 2-1 victory over Burnley to keep their title hopes on track after the referee Jon Moss awarded penalties to both sides and sent off home manager Arsene Wenger in injury time.
The former England international, who won the Premier League title in the 1994-95 season with Blackburn, is the only player to have scored 100 goals in the competition for two different clubs.
Images from Saturday's action in the Premier League.
Chelsea got their Premier League campaign on track after 20-year-old right back Reece James helped them to a 3-1 win at Brighton & Hove Albion with a spectacular goal on Monday.
Liverpool forward Sadio Mane scored his 100th goal for the club to help secure a 3-0 victory over lively Crystal Palace in the Premier League at Anfield on Saturday.
Ten-man Arsenal suffered a 3-0 Premier League defeat at Leicester City on Sunday in another blow to their hopes of finishing in the top four and qualifying for the Champions League.
Ole Gunnar Solskjaer's side, who had won their last ten away games in the Premier League, stay third on 27 points, a point behind second-placed Leicester.
TThe switch to five subs - up from three - brings the Premier League in line with other major competitions in Europe.
Sergio Aguero was acclaimed as "the best striker in the Premier League" by manager Manuel Pellegrini after his hat-trick helped Manchester City beat Chelsea 3-0 at Stamford Bridge on Saturday.
Chelsea striker Tammy Abraham scored a late opportunist double to secure a 3-0 home win for Chelsea over West Ham United in the English Premier League on Monday.
Of the 220 players who started for Premier League clubs at the weekend, only 73, or 33.2 per cent, were eligible to play for England.
Roberto Firmino's 90th-minute header sent Liverpool back to the top of the Premier League with a 2-1 victory over Tottenham Hotspur, whose 11-match unbeaten run came to an end on Wednesday.
Mason Greenwood's late winner earned Manchester United a 1-0 win at wasteful Wolverhampton Wanderers in the Premier League on Sunday, breaking the record for the longest unbeaten away run in English Football League history in the process.
Manchester City's hopes of closing the gap on the Premier League pacesetters were frustrated as they were held to a 1-1 draw at home to lowly West Bromwich Albion on Tuesday.
Arsenal has scored 10 goals in 11 league games this season to find themselves 15th in the Premier League
Photos from the EPL match played between Manchester City and West Bromwich Albion on Monday
IMAGES from the Premier League matches played on Sunday.
