While Sinner is into his fifth Grand Slam semi-final, Shelton, who turned pro in 2022, is set to play just his second after reaching the last four at the 2023 US Open.
Djokovic has declined to disclose whether he is vaccinated, citing privacy.
It was Novak Djokovic's first match this year after his Australian Open hopes were dashed when he was deported following an 11-day saga revolving around his decision not to have a COVID-19 vaccination.
Serum CEO Adar Poonawalla posted a video of him playing tennis, with a message for the unvaccinated Novak Djokovic.
Carlos Alcaraz said he has no doubt that top-ranked Jannik Sinner is the best player in the world on current form as the two young players continue to lay the foundations for an epic rivalry.
There is a petition circulating to allow Novak Djokovic to play at the US Open but the Serbian appears likely to miss the entire North American hardcourt swing barring a sudden change in COVID-19 protocols in the United States and Canada.
Nadal was much more than a claycourt bully, though. He spent more than 900 successive weeks from 2005 in the ATP's top 10, 209 of them at number one and at the age of 24 became the youngest player to complete the career Grand Slam.
World number one Novak Djokovic was released from Australian immigration detention on Monday after winning a court challenge to revive his bid to win a record 21st Grand Slam title at the upcoming Australian Open.
It took the COVID-19 pandemic to put a brake on Djokovic's 18-match unbeaten run in 2020, as he won the ATP Cup with Serbia, an eighth Australian Open title and a fifth Dubai Tennis Championships before the season came to a halt in early March.
At one stage, police deployed pepper spray.
The two cases shocked the tennis world with many fuming at how they were handled by the authorities.
Images from Day 3 of the 2022 Wimbledon Championships at the All England Lawn Tennis and Croquet Club in London, on Wednesday.
Djokovic has refused to take the vaccine and appears set to miss out on the year's last Grand Slam
The German was visibly distraught ahead of the trophy ceremony, appearing emotional as he fought back tears.
Novak Djokovic is still uncertain whether he will take part in the 2022 Australian Open but will soon make a decision, the World No 1 said after Serbia's 2-1 defeat by Croatia in the Davis Cup semi-finals on Friday.
Fonseca cruised through the first set before Fearnley found his groove in the second to level the match on a windy day in the California desert.
Djokovic, who has won nine titles at Melbourne Park, including the last three, confirmed on Tuesday that had received a vaccination exemption to allow him to bid for a record 21st major title at the Australian Open, which starts on January 17.
Here is a quick glance of all the highs and lows from Nadal's stupendous career:
World number one Novak Djokovic once again declined to reveal whether he has been vaccinated against COVID-19 and said he is unsure if he would defend his title at next year's Australian Open.
Images from Day 3 of the US Open, at Flushing Meadows, New York.
Unvaccinated tennis star Novak Djokovic won the right to take his fight against deportation from Australia to a Federal Court on Saturday after the government cancelled his visa for the second time over COVID-19 entry regulations.
'I'm not vaccinated and I'm not planning to get vaccinated so the only good news I can have is them removing the mandated green vaccine card'
American great Pete Sampras said he does not expect any player to match Novak Djokovic's feat of winning the men's year-end world number one ranking seven times.
Dimitrov was showing signs of fatigue from his three-hour third-round match earlier in the week and could do little to stop the Spanish world number three, who next faces Argentine Francisco Cerundolo.
Serbia's parliamentary speaker, Ivica Dacic, said on Monday he is concerned tennis star Novak Djokovic could still be deported from Australia despite winning his court case over his visa and vaccination exemption.
He was drawn in the toughest half of the draw with Nadal as well as in-form Spanish teenager Carlos Alcaraz and world number three Alexander Zverev, who could clash in the last eight.
Learner Tien became the youngest man to reach the Australian Open fourth round in 20 years
Osaka takes equity stake in crypto exchange FTX
The company is developing a peptide, which inhibits the coronavirus from infecting the human cell, expects to launch clinical trials in Britain this summer, he added.
Djokovic welcome to play if he can obtain visa, says Australian Open director
Djokovic had been favourite to win a 10th title at Melbourne Park and claim a 21st Grand Slam crown but the Serb now faces being deported from Australia.
Djokovic will be nowhere near the centre court after losing his bid to overturn a second visa cancellation.
Australian authorities scrambled on Sunday to file a legal defence of their decision to bar entry to tennis world number one Novak Djokovic over his COVID-19 vaccination status, as the Serbian superstar spent his fourth day in immigration detention.
Images from Day 6 at the French Open, at Roland Garros, in Paris, on Friday.
Carlos Alcaraz announced himself in Madrid when he played with a sore ankle but still dispatched three top five players -- Rafael Nadal, Djokovic and Alexander Zverev -- en route to his second Masters title, just days after his 19th birthday.
The reaction has been swift across the world to Novak Djokovic's visa has been cancelled for a second time by the Australian government.
Images from the French Open quarter-final between Rafael Nadal and Novak Djokovic at Roland Garros on Tuesday.
The 34-year-old is currently housed in a government detention hotel in the suburb of Carlton, 5 km (2 miles) north of Melbourne Park, after authorities cancelled his visa when he arrived in Australia.
Novak Djokovic secured a semi-final place at the ATP Finals with a 6-3, 6-2 victory over Russian Andrey Rublev on Wednesday, his 50th match win of the year, while Stefanos Tsitsipas withdrew from the tournament due to an elbow injury.
A US Open full of upsets and hungry, young contenders offered the latest sign that men's tennis has entered a new era
