Greece's Tsitsipas battled back from 3-5 down in the third set to eliminate Medvedev with a 6-3, 6-7(11), 7-6(1) win to set up a showdown on Friday with Rublev for the Red Group's other semi-final spot.
Carlos Alcaraz beat Novak Djokovic in the Wimbledon final to win his fourth Grand Slam title.
The prize money pool for this year's U.S. Open has been increased by 15% to $75 million, making it the largest purse in tennis history, the United States Tennis Association announced on Wednesday.
Daniil Medvedev handed Novak Djokovic his first loss of the year, defeating the world no. 1 6-4, 6-4 in Dubai.
Novak Djokovic reclaimed the world number one ranking from Carlos Alcaraz
Alcaraz returns to action at this week's Cincinnati Open, where he can gain ground on the Serb and Italian Jannik Sinner.
Australian Open organisers have issued a reminder to players and their entourages about their policy on "inappropriate flags" after a video emerged showing Novak Djokovic's father posing for pictures with fans holding Russian flags.
All the action from Day 4 at the Australian Open on Wednesday
As Rafael Nadal prepares to ride off into the sunset after a stellar career, his fellow professionals from eras old and new agree on one thing - the Spaniard remains an inspirational role model whose legacy has shaped tennis over the last 23 years.
Raducanu retires in Rome as back injury persists, Jabeur survives early scare
Roger Federer paid tribute to his retiring rival Rafael Nadal on Tuesday, telling the Spaniard he challenged him like no other player.
Carlos Alcaraz is the third Spaniard to reach the Wimbledon men's singles final after Manuel Santana and Rafael Nadal.
Novak Djokovic said he is preparing for the US Open as if he will be allowed to compete at the hardcourt major, despite his refusal to take the COVID-19 vaccine.
Australian court sets Jan 20 to issue reasons for dismissal of Djokovic case
Djokovic's coach Goran Ivanisevic said after the final that the world number one battled the injury
Images from Day 8 of the 2023 French Open at Roland Garros in Paris on Sunday.
Serbia's Novak Djokovic outclasses Russia's Andrey Rublev to set up a meeting with unseeded Tommy Paul in the semi-finals of the Australian Open on Wednesday.
Top seed Novak Djokovic produced a stellar display to sweep aside Croatian Marin Cilic 6-3, 6-4 in the final of the ATP 250 Tel Aviv Open on Sunday and clinch his third title of the season.
Italy's Sinner and Spain's Alcaraz have won two Grand Slams each this year, with Alcaraz beating Sinner in closely fought clashes at the French Open semi-finals and the China Open final.
The rematch between Carlos Alcaraz and Novak Djokovic was one of the most expensive get-in-final tickets in the history of the sport.
Jannik Sinner became the first Italian to win the ATP Finals title following a dominant 6-4, 6-4 victory over American Taylor Fritz.
Djokovic said his son had won his first tournament on the same day he won the Italian Open
'He's a bit of God, I'm not gonna lie'
Novak Djokovic produced a stunning performance to thrash Frances Tiafoe in his first match since winning Wimbledon in July to edge Team Europe ahead in the Laver Cup on Saturday.
Novak Djokovic advanced to a record-extending 10th Australian Open final with an emphatic win over American Tommy Paul.
The Australian government cancelled Novak Djokovic's visa for a second time on Friday, saying the World No 1, unvaccinated for COVID-19, may pose a risk to the community.
Novak Djokovic overcame a slow start to outclass Nick Kyrgios 4-6, 6-3, 6-4, 6-6 (7) in the final and win his seventh Wimbledon title in London on Sunday.
Serena Williams was included on the entry list for the US Open on Wednesday along with fellow former champion Novak Djokovic, who will not be able to compete due to his refusal to be vaccinated against COVID-19.
A round-up of all tennis action on Saturday.
Former world number one Novak Djokovic will miss the US Open after he said on Thursday that he will not be able to travel to New York for the tournament, having chosen not to be vaccinated against COVID-19.
Zverev had surgery on torn ligaments in his right ankle this month after he was forced to retire from his French Open semi-final against Rafael Nadal.
'He has left a huge legacy that will live for a very long time'
Novak Djokovic missed two of this year's four Grand Slams due to not being vaccinated against the novel coronavirus but the Serbian said he has no regrets about his decision.
World number two Novak Djokovic has withdrawn from the BNP Paribas Open in Indian Wells, the tournament announced on Wednesday, in the latest setback for the player due to his refusal to take the COVID-19 vaccine.
Novak Djokovic will begin his quest for a record-extending 10th Australian Open title against Roberto Carballes Baena.
A true legend of the game who paved the way and taught so many of us how to be as a player and as a person.
Sinner won in Cincinnati this week to claim his fifth title of a breakout season before the revelation that he avoided a ban over two positive tests
Tiley denies reports Djokovic will sue Tennis Australia
Novak Djokovic has offered financial support and any other help required to Ukrainian former world number 31 Sergiy Stakhovsky, who has enlisted in his country's reserve army amid Russia's invasion of its neighbour.
Danish teenager Holger Rune fought back from a set down to beat hot favourite Novak Djokovic 3-6, 6-3, 7-5 and win his first Masters title in Paris on Sunday.