Juergen Klopp returns to the scene of one his Liverpool side's most controversial victories of last season this Saturday with the man who fashioned it lining up against him.
Jose Mourinho's United side have 62 points and lead the Merseyside club by two with nine game remaining.
Liverpool manager Juergen Klopp is expecting his toughest test yet in a Merseyside derby when his side face local rivals Everton in the Premier League on Sunday.
Manchester City will return to action in the UEFA Champions League on Wednesday against RB Leipzig at the Etihad Stadium.
Images from the English Premier League matches played on Saturday.
It promises to be a tense and thrilling finale to the season but Liverpool, who have frittered away a seven-point lead, will need to regain their momentum quickly if they are to push for their first league title since 1990.
Tottenham Hotspur and Liverpool fans' joy at reaching the Champions League final has been dampened by the eye-watering costs of travelling to Madrid for the June 1 showdown.
A round-up of Saturday's matches in the English Premier League.
'Porto are a really, really good football team. We have to play at our limit 100 percent'
Images from Sunday's action in the Premier League.
The pain of missing out on a first domestic league crown for 29 years will be eased by the knowledge that European glory could be on the horizon for Liverpool
Manchester City forward Raheem Sterling struck twice as the Premier League champions beat Crystal Palace 3-1 at Selhurst Park on Sunday to go top of the table and heap pressure on title rivals Liverpool.
Bernardo Silva and Jack Grealish scored three minutes apart as Manchester City came from behind to beat Premier League newcomers Luton Town.
Liverpool's James Milner's converted a penalty on the stroke of half-time and Sadio Mane added a late second goal to secure a hard-fought 2-0 victory at Crystal Palace in the Premier League on Monday.
Images from the English Premier League matches played on Saturday, April 13.
Liverpool boss Juergen Klopp has said his team will be 'on fire' for the Champions League final
'That is how it is. How we created the moments was outstanding, how we caused them problems was outstanding, we controlled the game so well'
Daniel Sturridge's Liverpool career seemed to be heading for a premature end last season but the striker showed on Tuesday he may yet have an important role after taking his chance during a rare start in the Champions League win over Paris St Germain.
IMAGES from the Champions League 2nd semi-final first leg match between Barcelona and Liverpool at Nou Camp on Wednesday
The lack of a winter break in English football took its toll on Liverpool players' fitness levels and played a part in the Merseyside club's poor form since the start of the year, manager Juergen Klopp has said.
United stewards ejected the fan, who British media reported had targeted Liverpool defender Trent Alexander-Arnold, in the first half of the game.
For all their improvement under Klopp, European champions Liverpool have not won at Old Trafford under the German
Five-time European champions Liverpool are in the quarter-finals of this year's competition
Liverpool ripped apart Manchester City with three goals inside the opening 31 minutes as they won their Champions League quarter-final, first leg tie 3-0 on Wednesday.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
The 58-year-old pointed to the 26-point gap in the Premier League table between runners-up Liverpool and his fourth-placed former team as evidence of a massive gulf between the sides.
Liverpool manager Juergen Klopp has dismissed claims that it is the perfect time to face Tottenham Hotspur because of injuries to key players and concern over striker Harry Kane's form and freshness.
Holders Manchester City cruised into the Champions League quarter-finals for the seventh consecutive season with a 3-1 victory over FC Copenhagen.
Liverpool had been the better side for great swathes of the Premier League encounter at Stamford Bridge, but a combination of poor finishing and resilient Chelsea defending meant they entered the dying minutes trailing 1-0 to Eden Hazard's superb finish.
IMAGES from the English Premier League matches played on Wednesday.
Real Madrid coach Zinedine Zidane has warned Liverpool that his side are as hungry as ever to win the Champions League, rejecting claims that the Spanish giants might have lost their edge ahead of Saturday's final in Kiev.
Liverpool regained their place at the top of the English Premier League with a 2-0 win at Cardiff City on Sunday that restored their two-point lead over Manchester City
IMAGES from the soccer matches played across leagues on Friday
A number of top-flight players had signed up to represent their clubs in the virtual tournament to generate funds for Britain's National Health Service (NHS) during the COVID-19 pandemic. Wolverhampton Wanderers forward Diogo Jota won the ePremier League Invitational title for his club on Saturday
Liverpool's 1-1 draw at Everton could not save manager Brendan Rodgers from the sack.
Images from the EPL matches played on Saturday
Liverpool manager Juergen Klopp has urged the club's supporters to celebrate at home as the club prepare to lift the Premier League trophy following their clash with Chelsea on Wednesday. Klopp's Liverpool secured their first top-flight title in 30 years with seven games to spare and will be presented with the trophy on a special podium built on the Kop stand at Anfield.
A summary of Wednesday's matches in the UEFA Champions League.
Liverpool suffered a shock 2-1 loss to Championship side Wolverhampton Wanderers in the FA Cup fourth round on Saturday, handing manager Juergen Klopp a third home defeat in a row.
Reports in British media put the latest bid at 125 million euros.
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