While 40 have tried only nine times have both Williams sisters been beaten by the same player at the same tournament and that list reads like a Grand Slam Hall of Fame with names that include; Steffi Graf, Martina Hingis, Lindsay Davenport, Justine Henin and Kim Clijsters, who like Pliskova, pulled the double off at the US Open.
Karolina Pliskova won her first title of the year on Sunday with a 7-6(2), 6-4 victory over American CoCo Vandeweghe in the final of the Porsche Tennis Grand Prix.
The Australian won a tour-leading five titles this year including her second Grand Slam.
Former Wimbledon semi-finalist Angelique Kerber claimed her first grasscourt title with a 6-7(5), 6-3, 7-6(4) victory.
World number three Karolina Pliskova overcame a stern test to reach the semi-finals of the BNP Paribas Open on Wednesday after edging French Open champion Garbine Muguruza 7-6(2), 7-6(5) at Indian Wells.
Belinda Bencic of Switzerland and Danielle Collins were among those to win their first-round matches at the Adelaide International
Azarenka, who sits on the eight-person WTA players council, said that combating abuse was the group's top priority.
Karolina Pliskova stormed to her second WTA title of the year, beating Caroline Wozniacki 6-3, 6-4 in the Qatar Open in Doha on Saturday.
Hubert Hurkacz battled back from a set and a break down to beat Casper Ruud 5-7 6-3 6-2 on Saturday and reach the Canadian Masters final.
Former champions Novak Djokovic, Rafael Nadal and Serena Williams have all entered next month's Western & Southern Open in New York, which will serve as a tune-up for the US Open, tournament organisers said on Wednesday. Organisers of the August 20-28 event, which was relocated from Cincinnati this year because of COVID-19, said defending champions Daniil Medvedev and Madison Keys are also among the initial entries.
Croatia's Mirjana Lucic-Baroni could barely contain her joy after reaching the Australian Open semi-finals on Wednesday, 19 years after her only previous singles match win at Melbourne Park prior to her remarkable run.
What happens when sports stars have all the free time at hand and no play?
Simona Halep claimed the Italian Open in Rome on Monday
Karolina Pliskova suffered a narrow US Open defeat at the hands of Angelique Kerber on Saturday, but the Czech 10th seed also proved her mettle as one of the most dangerous attacking players in women's tennis.
'I have a lot of other goals, dreams that are in my mind and within my team and we'll certainly reset in the next couple of days ... enjoy some time together and then we go again. But really looking forward to the Olympics.'
Maria Sharapova will return to tournament action at the Brisbane International next month
Serena beat Sara Sorribes Tormo and Marie Bouzkova 2-6, 6-3, (13-11) in the women's doubles.
Barty said the key to the match was extending rallies on the warm day in Southern Florida.
Coco Gauff rallied from a break down in the final set to beat Swede Rebecca Peterson and reach the Indian Wells quarter-finals for the first time
Pliskova, a finalist at last year's US Open who reached the semi-finals at Indian Wells last week, relied on her booming groundstrokes and strong returning to dispatch her American opponent in 59 minutes.
Czech Karolina Pliskova crushed Frenchwoman Alize Cornet 6-0, 6-3 with a barrage of winners to win the Brisbane International title on Saturday and signal her intent for this month's Australian Open.
Japan's Kei Nishikori overcame Daniil Medvedev in the Brisbane International final on Sunday for his first ATP title in nearly three years and the 12th of his career.
American Sloane Stephens battled back to defeat defending champion Caroline Garcia at the Cincinnati Open.
Former world number one Karolina Pliskova is confident that splitting with coach David Kotyza will not be a hindrance as she attempts to go it alone over the home stretch of the season, leading up to the WTA Finals in Singapore next month.
Karolina Pliskova showed the steel of a world number one as she fought off a match point to claim a riveting 3-6, 7-5, 6-4 comeback win over Zhang Shuai in the US Open third round.
World No 4 Del Potro is still sidelined with a right knee injury sustained in Shanghai last month.
Maria Sharapova's US Open preparations took a major blow with the Russian World No 2 forced to withdraw from next week's WTA event in Toronto.
Czech Karolina Pliskova rose to the top of the WTA rankings without striking a ball on Tuesday as results at Wimbledon saw her overhaul Germany's Angelique Kerber.
Brady was sidelined by knee and foot injuries since the summer of 2021
Two-time winner Petra Kvitova and world number three Karolina Pliskova will be tough to beat at Wimbledon because the tournament's grass courts suit their games down to the ground, Serena Williams' coach Patrick Mouratoglou has said.
Serena Williams crashed out of the US Open after losing in the semi-final to Karolina Pliskova costing her a shot at a 23rd Grand Slam title and resulted in her losing her record 187th straight week at number one.
Canada's Bianca Andreescu upset Greek seventh seed Maria Sakkari to reach the last 32, while Japan's Taro Daniel crushed world number 15 Alexander Zverev.
Famous faces spotted at the finals:
A summary of Wednesday's action at the US Open.
Andy Murray will begin the defence of his Wimbledon title against a qualifier after the draw was made at the All England Club on Friday.
Karolina Pliskova warmed up for Wimbledon in the best possible fashion on Saturday by powering past Angelique Kerber 6-1, 6-4 to win the Eastbourne title.
World number two and top seed Caroline Wozniacki, runner-up at the south coast event last year, cruised into the semi-finals with a 6-4, 6-3 win over Australia's Ashleigh Barty.
'I think I started listening to them more when I watched 'Thor'. I listened to them even a few years ago, and I watched 'Thor' in Australia.'
Jelena Ostapenko enjoyed a winning end to her season with a 6-3, 6-1 triumph over Karolina Pliskova in her final White Group match at the WTA Finals on Thursday and vowed to return as a better player after her first taste of the event.
Three-time US Open champion Djokovic, who comes into the tournament having won his fifth Wimbledon title, is followed in the seedings by 2017 winner Rafael Nadal.